Media Library

Electrospinning has emerged as a versatile technique for fabricating nanofibrous scaffolds for biomedical applications, as their structure perfectly biomimics the native extracellular matrix (ECM). Recent advances in biofunctionalization of electrospun fibers, such as coating with natural proteins, enable improved control of cell interaction. Furthermore, advanced spinning techniques, such as coaxial electrospinning, allow incorporation of active ingredients and their controlled release.

Calcium−sulfur (Ca−S) batteries are considered promising candidates for large-scale energy storage owing to their high theoretical energy density, the natural abundance of both calcium and sulfur, and their inherent cost-effectiveness and sustainability.

Bioprinting is an emerging technology with the potential to fabricate functional in vitro 3D models of different tissues, enabling more predictive and physiological relevant drug development. However, suitable bioinks that fulfil good printability and biofunctionality, e.g., allowing cell adhesion and self-organization, are still limited.

Despite recent advances in neuropsychiatry, translational development for many targets remains challenging, particularly when receptors exist as families with complex subunit-dependent pharmacology and safety concerns. This is the case for NMDA receptor (NMDAR) antagonists. R,S-ketamine illustrates this issue.

This study demonstrates the implementation of a structured developability assessment strategy for sdAb conjugates. The approach integrates physicochemical and functional stability evaluations, supporting robust candidate selection, formulation development, and method optimization for this class of molecules.

Emerging immune-evasive viral variants threaten the efficacy of current vaccines, underscoring the need for strategies that elicit broad and durable protection. Heterologous prime-boost regimens combining distinct vaccine platforms can enhance humoral and cellular immunity through complementary mechanisms.