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Toxicological test methods generate raw data and provide instructions on how to use these to determine a final outcome such as a classification of test compounds as hits or non-hits.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel.

Biological 3D printing (bioprinting) is an extension of what is defined as additive manufacturing in the American Society for Testing and Materials (ASTM) and International Organization for Standardization (ISO) standards and is based on the automated printing of living cells and biomaterials.

SCZ neural progenitors displayed altered expression and phosphorylation patterns related to Wnt and MAPK signaling, protein synthesis, cell cycle regulation and DNA damage response.

Endothelial cells form the inner lining of our vascular system facilitating the supply of oxygen and nutrients to and removal of waste from surrounding tissues. In this work, we investigate the differences between ECs from various tissues regarding their biochemical composition, angiogenic potential, adaptation to flow, and coculture properties in vitro in the context of diabetes research.

The researchers have succeeded in demonstrating the influence of a brain region responsible for emotions, the amygdala, on the manifestation of anxiety symptoms by specifically altering the communication between nerve cells.