In unserer Mediathek finden Sie unser News-Archiv, Publikationen unserer Wissenschaftler:innen, Flyer zu unterschiedlichen Themen, Clips zu unseren Kernkompetenzen und die Paper Awards.


Juli 2024

Autoren: Simon Woelfel, Joel Dütschler, Daniel Junker, Marius König, Georg Leinenkugel, Nicole Graf, Claudia Krieger, Samuel Truniger, Annett Franke, Seraina Koller, Katline Metzger-Peter, Melanie Oberholzer, Nicola Frei, Nora Geissler, Peter Schaub, Star Sign Investigators, Werner C. Albrich, Matthias Friedrich, Jan Hendrik Niess, Nicole Schneiderhan-Marra, Alex Dulovic, Wolfgang Korte, Justus J. Bürgi, Stephan Brand

Systemic and Mucosal Immunogenicity of Monovalent XBB.1.5-Adapted COVID-19 mRNA Vaccines in Patients with Inflammatory Bowel Disease

Recently updated COVID-19 mRNA vaccines encode the spike protein of the omicron subvariant XBB.1.5 and are recommended for patients with inflammatory bowel disease (IBD) on immunosuppressive treatment. Nonetheless, their immunogenicity in patients with IBD against rapidly expanding virus variants remains unknown.


Juni 2024

Autoren: Jonas Haas; Nils Rieger; Michael Schlegel; Kevin Strobel; Jannik C. Meyer

Nanometer-scale electron beam shaping with thickness controlled and stacked nanostructured graphite

The generation of small electron probes is the basis for various techniques in which such a probe is scanned across a sample, and special probe shapes like vortices can be desirable, e.g., to gain insight into magnetic properties. 


Juni 2024

Autoren: Kevin R. Strobel, Michael Schlegel, Mitisha Jain, Silvan Kretschmer, Arkady V. Krasheninnikov, Jannik C. Meyer

Temperature-dependence of beam-driven dynamics in graphene-fullerene sandwiches

C60 fullerenes encapsulated between graphene sheets were investigated by aberration-corrected high-resolution transmission electron microscopy at different temperatures, namely about 93 K, 293 K and 733 K, and by molecular dynamics simulations. We studied beam-induced dynamics of the C60 fullerenes and the encapsulating graphene, measured the critical doses for the initial damage to the fullerenes and followed the beam-induced polymerization. We find that, while the dose<!


Mai 2024

Autoren: Umair Nisar, Joachim Bansmann, Marco Hebel, Benedikt Reichel, Marilena Mancini, Margret Wohlfahrt-Mehrens, Markus Hölzle, Peter Axmann

Borate modified Co-free LiNi0.5Mn1.5O4 cathode material: A pathway to superior interface and cycling stability in LNMO/graphite full-cells

Spherical high quality, industrial-relevant LNMO materials developed. LNMO/electrolyte interface stabilized with borate-based interphase layer. Borate-modified LNMO exhibits superior electrochemical performance. The primary aging mechanism stems from LNMO/electrolyte interface instability.


Mai 2024

Autoren: Tengku Ibrahim Maulana, Claudia Teufel, Madalena Cipriano, Julia Roosz, Lisa Lazarevski, Francinja E. van den Hil, Lukas Scheller, Valeria Orlova, André Koch, Michael Hudecek, Miriam Alb, Peter Loskill

Breast cancer-on-chip for patient-specific efficacy and safety testing of CAR-T cells

Physiologically relevant human models that recapitulate the challenges of solid tumors and the tumor microenvironment are highly desired in the chimeric antigen receptor (CAR)-T cell field. We developed a breast cancer-on-chip model with an integrated endothelial barrier that enables the transmigration of perfused immune cells, their infiltration into the tumor, and concomitant monitoring of cytokine release during perfused culture.


März 2024

Autoren: Lu Fan, Ole Jung, Markus Herrmann, Marina Shirokikh, Sanja Stojanovic, Stevo Najman, Fabian Körte, Xin Xiong, Katja Schenke-Layland, Mike Barbeck

Deciphering UVA/Riboflavin Collagen Crosslinking: A Pathway to Improve Biomedical Materials

Die Kollagenvernetzung mit ultravioletten A-Strahlen und Riboflavin hat sich seit den 1990er Jahren zu einem zentralen Verfahren in der klinischen Therapie, insbesondere in der Augenheilkunde, entwickelt. Trotz der klinischen Anwendung sind weitere Untersuchungen erforderlich, da der genaue Mechanismus nicht klar ist und ein verfeinertes Herstellungsverfahren erforderlich ist.


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