Monoclonal antibodies allow innovative, targeted therapy approaches in oncology
Monoclonal antibodies are used as innovative therapeutic tools in oncology and other indications. In preclinical development, in addition to a demonstration of efficacy, further parameters such as the dynamics of epitope-specific cellular uptake or the intracellular processing of therapeutic immunoglobulins are to be determined.
Confocal fluorescence and live cell microscopy
Quantitative analysis of microscopic image data
3D and 4D reconstructions and animations
Microscopy: Carl Zeiss CLSM + Cell Observer SD, Molecular Devices ImageXpress Micro confocal
Software: Oxford Instruments IMARIS 10, Molecular Devices MetaXpress 6.7