Degradation and Remodeling of Implant Materials
Group Leader Biophotonics & Spectroscopy
Head of Biomedicine & Material Sciences
Interaction between (tissue-engineered) implants and the recipient
Build-up and degradation processes at biological interfaces, such as vital implants, can be characterized using non-destructive imaging in vitro as well as ex vivo:
- Investigation of degradation mechanisms of biodegradable implant materials
- Visualization and quantification of processes of tissue formation
- Identification of foreign body reactions and fibrotic changes
- Prediction of potential immune response by in situ phenotyping of immune cells (e.g. macrophages)
Evaluation
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Visual documentation
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Mass, molecular weight
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Mechanical properties (based on ISO 25539), rheology
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Release kinetics of active substances
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Detection of degradation products (based on DIN EN ISO 10993-13 and -15)
Other services
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Development of product-specific test plans according to relevant standards
Evaluation
- Optical documentation
- Mass, molecular weight
- Mechanical properties (based on ISO 25539), rheology
- Release kinetics of active ingredients
- Detection of degradation products (based on DIN EN ISO 10993-13 and -15)
Further services
- Development of product-specific test plans according to relevant standards
Projects
InGel-NxG- Next generation injectable adaptive hydrogels
LAA-Okkluder - Development of a novel atrial appendage closure system for stroke prophylaxis
ASD-Okkluder - Development of a bioresorbable occluder for the treatment of atrial septal defects
NMI Natural and Medical Sciences Institute
at the University of Tübingen
Markwiesenstraße 55, 72770 Reutlingen
Tel.: +49 7121 51530-0
Mail: info@nmi.de
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