Dr. Julia Marzi
Group Leader Biophotonics & Spectroscopy

+49 7121 51530-894

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Dr. Hanna Hartmann
Head of Biomedicine & Material Sciences
Group Leader Regenerative Biomaterials

+49 7121 51530-872

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Interaction between (tissue-engineered) implants and the recipient

Build-up and degradation processes at biological interfaces, such as vital implants, can be characterized using non-destructive imaging in vitro as well as ex vivo:

• Investigation of degradation mechanisms of biodegradable implant materials
• Visualization and quantification of processes of tissue formation
• Identification of foreign body reactions and fibrotic changes
• Prediction of potential immune response by in situ phenotyping of immune cells (e.g. macrophages)

Evaluation

• Visual documentation

• Mass, molecular weight

• Mechanical properties (based on ISO 25539), rheology

• Release kinetics of active substances

• Detection of degradation products (based on DIN EN ISO 10993-13 and -15)

Other services

• Development of product-specific test plans according to relevant standards

InGel-NxG- Next generation injectable adaptive hydrogels

LAA-Okkluder - Development of a novel atrial appendage closure system for stroke prophylaxis

ASD-Okkluder - Development of a bioresorbable occluder for the treatment of atrial septal defects