Degradation and Remodeling of Implant Materials

Dr. Julia Marzi
Next Generation Cellular and Organotypic Assays
Senior Scientist

Interaction between (tissue-engineered) implants and the recipient

Assembly and disassembly processes of vital implants obtained through tissue engineering. These can be characterized in vitro and ex vivo using non-destructive imaging:

  • Investigation of degradation mechanisms of biodegradable implant materials
  • Visualization and quantification of processes of tissue formation
  • Identification of foreign body reactions and fibrotic changes
  • Prediction of potential immune response by in situ phenotyping of immune cells (e.g. macrophages)