Electrophysiological measurements of ion channel physiology in Xenopus oocytes
Automated Xenopus oocyte assays, implemented on the Roobocyte platform, offer high-quality voltage-clamp electrophysiology for drug screening and compound profiling on ion channel targets:
Oocyte recording offers several benefits over other methods:
Standard assays are routinely available and can be started at any time. They generally test for the potency of compounds in blocking or modulating the target ion channel. Using one oocyte per data point and sufficient compound incubation time, high data quality is guaranteed. Dose-response curves are carried out by testing each data point on an individual oocyte.
Ligand-gated Ion Channels
Ligand-gated ion channels require fast and reliable compound applications. We offer services with standard and improved recording heads. Our proprietary HPS recording heads ensure high-quality recordings.