Identification of new target proteins for pancreatic carcinoma Early stages of pancreatic tumors often cause no symptoms, while later-stage symptoms are often nonspecific. Pancreatic cancer is therefo
ERA-Net Eurotransbio: Models for Alzheimer's and similar diseases, drug development based on the mitochondrial cascade hypothesis Mitochondria are the powerhouses of cells. Recent investigations sugge
Identifizierung von Biomarkern zur Vorhersage des Ansprechens und der Resistenz gegenüber VEGFR/mTOR-Inhibitoren beim Nierenkarzinom
Agents are tested using neurons derived from induced pluripotent stem cells in comparison to animal models. Neurons derived from induced pluripotent stem cells (iPSCs) can be used as a relevant, near-
In a new approach, genetic tools are used to introduce additional mitochondrial dysfunction into transgenic mice with pathogenic Alzheimer's disease proteins to model age-related metabolic deficits. I
Traumatic experiences and stress are major contributors to anxiety disorders. In this context, a specific brain region, the amygdala, plays an important role by modulating other brain regions, such as
Psychoses describe an extremely heterogeneous group of diseases. As a result, diagnoses, prognoses and treatment decisions for individual patients are challenging. Within the project, biomarker signat
High-throughput sequencing of all mRNA molecules from patient tissues is used for personalized, predictive diagnostics as well as drug testing in vitro. Since the brain is not readily accessible for t
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Accredited Testing Services Accredited testing services according to DIN EN ISO/IEC 17025:2018 for chemical characterization of materials for medical devices Numerous tests must be carried out before