3G-BioInk
Description
At the NMI, the focus is on research work on the production, fragmentation, sterilization and modification of electrospun bulk, hollow and core-sheath fibres for integration into bioinks for the production of innovative organ-like tissue models. Through a defined fiber morphology and fiber modification, the following limitations of previous tissue models are to be overcome:
(i) Initiation of directed cell growth (totographic guide rail) through an integration of biofunctionalized fibers (e.g. surface coating)
(ii) Site-resolved drug release through targeted placement of bulk or core-sheath fibers loaded with drugs/growth factors (e.g. in complex co-cultures)
(iii) Sufficient electrical stimulation by generating conductive structures using CNT-coated bulk fibers
(iv) Targeted nutrient supply even in larger or denser constructs through the integration of hollow fibers
Projectlead
Dr. Hanna Hartmann
Head of Biomedicine & Material Sciences
NMI Natural and Medical Sciences Institute
at the University of Tübingen
Markwiesenstraße 55, 72770 Reutlingen
Tel.: +49 7121 51530-0
Mail: info@nmi.de
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