Dr. Timm Danker

Next Generation Cellular and Organotypic Assays Senior Scientist

Dr. Timm Danker

Next Generation Cellular and Organotypic Assays
Senior Scientist

After completing his PhD at the University of Münster in 1999, he joined the NMI TT Pharmaservices in 2006 and moved to the NMI in 2022, where he is group leader of the electrophysiology group. His research interests include the use of automated electrophysiology, patch clamp, and oocyte recordings.

Selected publications

  • Early Identification of HERG Liability in Drug Discovery Programs by Automated Patch Clamp. Frontiers in Pharmacology, 2014, DOI: 10.3389/fphar.2014.00203
  • Efficient Binding of 4/7 α-Conotoxins to Nicotinic Α4β2 Receptors Is Prevented by R185 and P195 in the Α4 Subunit. Molecular Pharmacology, 2012, DOI: 10.1124/mol.112.078683
  • Catch and Patch: A Pipette-Based Approach for Automating Patch Clamp That Enables Cell Selection and Fast Compound Application. ASSAY and Drug Development Technologies, 2016, DOI: 10.1089/adt.2015.696
  • Nuclear hourglass technique: an approach that detects electrically open nuclear pores in Xenopus laevis oocyte. Proceedings of the National Academy of Sciences of the United States of America, 1999, DOI: 10.13530–35
  • Using atomic force microscopy to investigate patch-clamped nuclear membrane. Cell Biology International, 1997, DOI: 10.1006/cbir.1997.0219