MEA recordings

Dr. Udo Kraushaar
Group Leader Electrophysiology

+49 7121 51530-851

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MEA (microelectrode array) provides extracellular recordings with optional optical or electrical stimulation

It is performed on electrogenic tissue on top of substrate-integrated electrodes.

MEA has several advantages over other methods of electrophysiology:

• Information on the network level
• non-invasive
• long-term recordings, cells can be cultured for days or weeks
• "holistic" ion channel interactions

Application

• Safety pharmacology (convulsive effects on neurons, cardiac arrhythmias on cardiac cells)
• Neurotoxicity; neuronal modulation; LTP (long-term potentiation)
• Neurodegeneration (organotypic cultivation on brain slices/retina)
• MoA connection
• Diabetes research
• Retina research

MEA recordings can be performed with various models, including neurons, cardiomyocytes, brain slices, iPSC-derived neurons/cardiomyocytes, heart slices, etc. Contact us for more information.