Dr. Anne Zeck

Anne Zeck earned her Ph.D. from the Technical University of Munich in 2001 and subsequently worked as a postdoctoral researcher in Boston until 2004. From 2007 to 2011, she led a research group at Roche Diagnostics in Penzberg and was then head of the Bioanalytics Group at the NMI until 2025. Since 2026, she is speaker of the field of competence "BioDev Center".

Her service portfolio and, at the same time, her research focus encompasses the production, purification, and detailed characterization of biomolecules for therapeutic, diagnostic, or enzymatic use, particularly using modern mass spectrometry.

In addition to her research activities, she has been teaching courses for many years at the University of Tübingen, Reutlingen University, and Esslingen University of Applied Sciences. Furthermore, she brings extensive experience as a reviewer and guest editor for scientific journals and funding organizations such as the Good Food Institute (GFI).

Selected publications

• Developability Evaluation of Single-Domain Antibody-Chelator Conjugates for Diagnostic Radiotracers. Antibodies, 2026, DOI: 10.3390/5020022
• Development of a PNGase Rc Column for Online Deglycosylation of Complex Glycoproteins during HDX-MS. Mass spectrometry, 2023, DOI: 10.1021/3c00268
• A Novel PNGase Rc for Improved Protein N-Deglycosylation in Bioanalytics and Hydrogen–Deuterium Exchange Coupled With Mass Spectrometry Epitope Mapping under Challenging Conditions. Anal. Chem., 2022, DOI: 10.1021/.2c01748
• Tris(hydroxymethyl)aminomethane Compatibility with N-Hydroxysuccinimide Ester Chemistry: Biotinylation of Peptides and Proteins in TRIS Buffer. Bioconjug Chem., 2021, DOI: 10.101542
• Cysteine in cell culture media induces acidic IgG1 species by disrupting the disulfide bond network. Biotechnol Bioeng, 2021, DOI: 10.1002/bit.27628
• HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1. Antibodies, 2021, DOI: 10.3390/10010011
• NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics, 2020, DOI: 10.10119.001677

ORCID: 0000-0001-7330-1654