NatInk (DE)

The goal of 3D bioprinting is to generate biomimetic-inspired 3D structures with high spatial resolution that mimic the intricate internal architecture of the target tissue. In this regard, it is a great challenge to develop suitable strategies and bio-inks that enable printing with good dimensional stability while being compatible with cells and allowing the exchange of nutrients and metabolites.

A novel biochip ink is being developed that incorporates capillary-sized electrospun hollow fiber fragments to achieve an improvement in the diffusion properties of the hydrogel. For this purpose, in addition to incorporating the hollow fibers into novel inks, suitable 3D printing processes are being developed and evaluated simultaneously.

Fiber integration is expected to close the supply gap in 3D bioprinting while maintaining high cell viability and print quality. This approach therefore provides a platform for diverse, future applications in the fields of medical technology, in vitro diagnostics and in vitro meat production.