September 2023

Authors: Tom Stumpp, Michael Mierzejewski, Domenic Pascual, Angelika Stumpf, Peter D.Jones

Scalable mesh microelectrode arrays for neural spheroids and organoids

Introduction: Neural organoids promise to help understand the human brain and develop treatments for neurological diseases. Electrophysiological recordings are essential in neural models to evaluate the activity of neural circuits. Mesh microelectrode arrays (MEAs) have been demonstrated to be suitable for organoids and spheroids, and there is demand for easy-to-use devices that can be manufactured at scale. Methods: We present a new mesh MEA device with an easyto-use design.