March 2024

Authors: Lu Fan, Ole Jung, Markus Herrmann, Marina Shirokikh, Sanja Stojanovic, Stevo Najman, Fabian Körte, Xin Xiong, Katja Schenke-Layland, Mike Barbeck

Deciphering UVA/Riboflavin Collagen Crosslinking: A Pathway to Improve Biomedical Materials

Collagen crosslinking employing ultraviolet A rays and riboflavin has emerged as a pivotal technique in clinical therapies, especially in ophthalmology since the 1990s. Despite its clinical adoption, the lack of clarity of the detailed mechanism and the imperative for a refined manufacturing process necessitates further investigation.