Publikationen

2020 |
Interference With Complex IV as a Model of Age-Related Decline in Synaptic Connectivity
Martin Kriebel, Julia Ebel, Florian Battke, Stefan Griesbach, Hansjürgen Volkmer
Front. Mol. Neurosci., 24 March 2020 https://doi.org/10.3389/fnmol.2020.00043
2020
Zur Publikation
2020 |
Incorporation of Stem Cell-Derived Astrocytes into Neuronal Organoids to Allow Neuro-Glial Interactions in Toxicological Studies
Markus Brüll, Anna-Sophie Spreng, Simon Gutbier, Dominik Loser, Alice Krebs, Marvin Reich, Udo Kraushaar, Markus Britschgi, Marcel Leist
ALTEX. 2020 Mar 7 doi:10.14573/altex.1911111
2020
Zur Publikation
2020 |
A mass spectrometry guided approach for the identification of novel vaccine candidates in gramnegative pathogens
Hornburg D, Kruse T, Anderl F, Daschkin C, Semper R P, Klar K, Guenther A, Mejías-Luque R, Schneiderhan-Marra N, Mann M, Meissner F & Gerhard M
Sci Rep 9, 17401 (2019) https://doi.org/10.1038/s41598-019-53493-8
2020
Zur Publikation
2020 |
A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer
Rammensee H-G, Wiesmüller K-H, Chandran P A, Zelab H, Rusch E, Gouttefangea C, Kowalewski D J, Di Marco M, Hean S P, Walz J S, Gloria Y C, Bödder J, Schertel J-M, Tunger A, Müller L, Kießler M, Wehner R, Schmitz M, Jakobi M, Schneiderhan-Marra N, Klein R, Laske K, Artzner K, Backert L, Schuster H, Schwenck J, Weber A N R, Pichler B J, Kneilling M, la Fougère C, Forchhammer S, Metzler G, Bauer J, Weide B, Schippert W, Stevanovic S u. Löffler M W
Journal for ImmunoTherapy of Cancer (2019) 7:307 https://doi.org/10.1186/s40425-019-0796-5
2020
Zur Publikation
2019 |
The role of the GABAA receptor Alpha 1 subunit in the ventral hippocampus in stress resilience
Ardi Z, Richter-Levin A, Xu L, Cao X, Volkmer H, Stork O, Richter-Levin G
Sci Rep. 2019 Sep 18;9(1):13513. doi: 10.1038/s41598-019-49824-4.
2019
Zur Publikation
2019 |
Assay Procedures for Compound Testing of hiPSC-Derived Cardiomyocytes Using Multiwell Microelectrode Arrays
Udo Kraushaar and Elke Guenther
Cell-Based Assays Using iPSCs for Drug Development and Testing (Mandenius C-F, Ross JA, eds), pp 197–208. New York, NY: Springer New York.
2019
Zur Publikation
2019 |
Comparative characterization of humaninduced pluripotent stem cells (hiPSC) derived from patients with schizophreniaand autism
Grunwald L-M, Stock R, Haag K, Buckenmaier S, Eberle M-C, Wildgruber D, Storchak H, Kriebel M, Weißgraeber S, Mathew L, Loos M, Li kw, Kraushaar U, Fallgatter AJ, Volkmer H
Translational Psychiatry (2019) 9:179
2019
Zur Publikation
2019 |
Regenerative potential of adipocytes in hypertrophic scars is mediated by myofibroblast reprogramming
Hoerst K, van den Broek L, Sachse C, Klein O, von Fritschen U, Gibbs S, Hedtrich S
Journal of Molecular Medicine, June 2019, Volume 97, Issue 6, pp 761–775
2019
Zur Publikation
2019 |
MEK inhibitors activate Wnt signalling and inducestem cell plasticity in colorectal cancer
Zhan T, Ambrosi G, Wandmacher AM, Rauscher B, Betge J, Rindtorff N, Häussler R, Hinsenkamp I, Bamberg L, Hessling B, Müller-Decker K, Erdmann G, Burgermeister E, Ebert MP, Boutros M
Nature Communications, 2019, 10:2197, https://doi.org/10.1038/s41467-019-09898-0
2019
Zur Publikation
2019 |
Heparin Differentially Impacts Gene Expression of Stromal Cells from Various Tissues
Laner-Plamberger S, Oeller M, Poupardin R, Krisch L, Hochmann S, Kalathur R, Pachler K, Kreutzer C, Erdmann G, Rohde E, Strunk D, Schallmoser K
Scientific Reports (2019) 9:7258
2019
Zur Publikation
2019 |
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, Keilholz U, Haybaeck J, Erdmann G, Sachse C, Templin M, Hoffmann J, Boerries M, Schäfer R, Regenbrecht C
PLoS Genet 15(3): e1008076.
2019
Zur Publikation
2019 |
A Strategy to Optimize the Generation of Stable Chromobody Cell Lines for Visualization and Quantification of Endogenous Proteins in Living Cells
Keller B, Maier J, Weldle M, Segan S, Traenkle B, Rothbauer U
Antibodies 2019, 8, 10; doi:10.3390/antib8010010
2019
Zur Publikation
2019 |
Application of Mass Spectrometry-Based Immunoassays for the Species- and Tissue-Specific Quantification of Banned Processed Animal Proteins in Feeds
Steinhilber A, Schmidt F, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos T, Poetz O
Analytical Chemistry. 2019 Feb 27. doi: 10.1021/acs.analchem.8b04652 Epub ahead of print
2019
Zur Publikation
2018 |
Serum inflammatory profile for the discrimination of clinical subtypes in Parkinson’s disease
Yilmaz R, Strafella A, Bernard A, Schulte C, van den Huevel L, Schneiderhan-Marra N, Knorpp T, Joos T, Leypoldt F, Geritz J, Hansen C, Apel A, Gasser T, Lang A, Berg D, Maetzler W, Marras C
Front Neurol., 2018 Dec 21 DOI:/10.3389/fneur.2018.01123
2018
Zur Publikation
2018 |
Imaging fibrosis in inflammatory diseases: Targeting exposed extracellular matrix
Beziere N, Fuchs K, Maurer A, Reischl B, Brück J, Ghoreschi K, Carvajal Berrio D, Schenke-Layland K, Kohlhofer U, Quintanilla-Martinez L, Gawaz M, Kneilling M, Pichler B
Theranostics in press
2018
Zur Publikation
2018 |
Chromobodies to quantify changes of endogenous protein concentration in living cells
Keller BM, Maier J, Secker KA, Egetemaier SM, Parfyonova Y, Rothbauer U, Traenkle B
Mol Cell Proteomics. 2018 Dec;17(12):2517-2533. doi: 10.1074/mcp.TIR118.000914. Epub 2018 Sep 18.
2018
Zur Publikation
2018 |
Comparative study of MSCA-1 and CD146 isolated periosteal cell subpopulations
Umrath F, Thomalla C, Pöschel S, Schenke-Layland K, Reinert S, Alexander D
Cell Physiol Biochem. 2018;51(3):1193-1206. doi: 10.1159/000495497. Epub 2018 Dec 12.
2018
Zur Publikation
2018 |
Mouse Hepatomas with Ha-ras and B-raf Mutations Differ in Mitogen-Activated Protein Kinase Signaling and Response to Constitutive Androstane Receptor Activation
Braeuning A, Kollotzek F, Zeller E, Knorpp T, Templin MF, Schwarz M
Drug Metab Dispos. 2018 Nov;46(11):1462-1465. doi: 10.1124/dmd.118.083014. Epub 2018 Aug 16.
2018
Zur Publikation
2018 |
A high-throughput pipeline for validation of antibodies
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, Nyman TA, Stensland ME, Zhou W, de Souza GA, Holden L, Stuchly J, Templin M, Lund-Johansen F
Nat Methods. 2018 Nov;15(11):909-912. doi: 10.1038/s41592-018-0179-8. Epub 2018 Oct 30.
2018
Zur Publikation
2018 |
Stem cell-based organ-on-a-chip models for diabetes research
Rogal J, Zbinden A, Schenke-Layland K, Loskill P
Adv Drug Deliv Rev 2018 in press (Review)
2018
Zur Publikation
2018 |
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
Blinova K, Dang Q, Millard D, Smith G, Pierson J, Guo L, Brock M, Lu HR, Kraushaar U, Zeng H, Shi H, Zhang X, Sawada K, Osada T, Kanda Y, Sekino Y, Pang L, Feaster TK, Kettenhofen R, Stockbridge N, Strauss DG, Gintant G
Cell Rep. 2018 Sep 25;24(13):3582-3592. doi: 10.1016/j.celrep.2018.08.079.
2018
Zur Publikation
2018 |
Species Differentiation and Quantification of Processed Animal Proteins and Blood Products in Fish Feed Using an 8-Plex Mass Spectrometry-Based Immunoassay
Steinhilber AE, Schmidt FF, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos TO, Poetz O
J Agric Food Chem. 2018 Oct 3;66(39):10327-10335. doi: 10.1021/acs.jafc.8b03934. Epub 2018 Sep 24.
2018
Zur Publikation
2018 |
Improved long-term durability of allogeneic heart valves in the orthotopic sheep model
Biermann AC, Marzi J, Brauchle E, Wichmann JL, Arendt CT, Puntmann V, Nagel E, Abdelaziz S, Winter AG, Brockbank KGM, Layland S, Schenke-Layland K, Stock UA
Eur J Cardiothorac Surg. 2018 Aug 24. doi: 10.1093/ejcts/ezy292. [Epub ahead of print]
2018
Zur Publikation
2018 |
Electrode-size dependent thresholds in subretinal neuroprosthetic stimulation
Corna A, Herrmann T, Zeck G.
J Neural Eng. 2018 Aug;15(4):045003. doi: 10.1088/1741-2552/aac1c8. Epub 2018 May 2.
2018
Zur Publikation
2018 |
Biomechanical and biomolecular characterization of ECM in human colon carcinomas
Brauchle E, Kasper J, Daum R, Schierbaum N, Falch C, Kirschniak A, Schäffer T, Schenke-Layland K
Matrix Biol. 2018 Aug;68-69:180-193. doi: 10.1016/j.matbio.2018.03.016. Epub 2018 Mar 29.
2018
Zur Publikation
2018 |
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study
Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM, Wu JC, Li Y, Luerman G, Anson B, Guo L, Clements M, Abassi YA, Ross J, Pierson J, Gintant G.
Toxicol Sci. 2018 Aug 1;164(2):550-562. doi: 10.1093/toxsci/kfy110.
2018
Zur Publikation
2018 |
Increased Energy Expenditure, Lipolysis and Hyperinsulinemia Confer Resistance to Central Obesity and Type 2 Diabetes in Mice Lacking Alpha2α-Adrenoceptors
Ruohonen ST, Valve L, Tuomainen K, Ailanen L, Röyttä M, Manz G, Baur N, Joos TO, Savontaus E, Scheinin M
Neuroendocrinology. 2018 Jul 24. doi: 10.1159/000492387. [Epub ahead of print]
2018
Zur Publikation
2018 |
Influence of aflibercept on platelet activation profile
Sobolewska B, Golenko J, Poeschel S, Grimmel C, Gatsiou A, Sopova K, Biedermann T, Schenke-Layland K, Stellos K, Ziemssen F
Exp Eye Res. 2018 Oct; 175:166-172. doi: 10.1016/j.exer.2018.06.009. Epub 2018 Jun 15. PMID: 29908884.
2018
Zur Publikation
2018 |
Combining two photon microscopy and CMOS MEA to uncover the mechanism of aberrant activity in blind retina
Lee M-J, Srivastava P, Rogerson L, Berens P, Euler T, Schubert T, Zeck G
MEA Meeting 2018, 10.3389/conf.fncel.2018.38.00022, 2018
2018
Zur Publikation
2018 |
Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report
Mulder P, de Korte T, Dragicevic E, Kraushaar U, Printemps R, Vlaming MLH, Braam SR, Valentin JP.
J Pharmacol Toxicol Methods. 2018 May-Jun;91:36-42. doi: 10.1016/j.vascn.2018.01.003. Epub 2018 Feb 4.
2018
Zur Publikation
2018 |
Low-picomolar, label-free procalcitonin analytical detection with an electrolyte-gated organic field-effect transistor based electronic immunosensor. Biosens Bioelectron
Seshadri P, Manoli K, Schneiderhan-Marra N, Anthes U, Wierzchowiec P, Bonrad K, Di Franco C, Torsi L.
Biosens Bioelectron. 2018 May 1;104:113-119. doi: 10.1016/j.bios.2017.12.041. Epub 2017 Dec 26.
2018
Zur Publikation
2018 |
PGRMC1 Predicts Poor Prognosis and Promotes Tumour Progression of Breast Cancer through Upregulation of ERα Expression
Willibald M, Stahlhut V, Stamm N, Gierke B, Pawlak M, Fehm T, Neubauer H
Senologie. 2018; 15(02):e52. DOI: 10.1055/s-0038-1651821
2018
Zur Publikation
2018 |
Peptide-Based Sandwich Immunoassay for the Quantification of the Membrane Transporter Multidrug Resistance Protein
Poetz O, Dieze T, Hammer H, Weiß F, Sommersdorf C, Templin MF, Esdar C, Zimmermann A, Stevanovic S, Bedke J, Stenzl A, Joos TO.
Anal Chem. 2018 May 1;90(9):5788-5794. doi: 10.1021/acs.analchem.8b00152. Epub 2018 Apr 12.
2018
Zur Publikation
2018 |
Speed up to find the right ones: rapid discovery of functional nanobodies
Rothbauer U
Nat Struct Mol Biol. 2018 Mar;25(3):199-201.
2018
Zur Publikation
2018 |
Mass Spectrometry-Based Immunoassay for the Quantification of Banned Ruminant Processed Animal Proteins in Vegetal Feeds
Steinhilber AE, Schmidt FF, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos T, Poetz O
Anal Chem. 2018 Mar 20;90(6):4135-4143. doi: 10.1021/acs.analchem.8b00120. Epub 2018 Mar 7.
2018
Zur Publikation
2018 |
A spike sorting toolbox for up to thousands of electrodes validated with ground truth recordings in vitro and in vivo
Yger P, Spampinato GLB, Esposito E, Lefebvre B, Deny S, Gardella C, Zeck G, Picaud S, Duebel J, Marre O
Elife. 2018 Mar 20;7. pii: e34518. doi: 10.7554/eLife.34518.
2018
Zur Publikation
2018 |
A peptide tag-specific nanobody enables high-quality labeling for dSTORM imaging
Virant D, Traenkle B, Maier J, Kaiser PD, Bodenhöfer M, Schmees C, Vojnovic I, Pisak-Lukáts B, Endesfelder U, Rothbauer U
Nature Communications. 2018 Mar;9:930. DOI:10.1038/s41467-018-03191-2
2018
Zur Publikation
2018 |
Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
de Boussac H, Gondeau C, Briolotti P, Duret C, Treindl F, Römer M, Fabre JM, Herrero A, Ramos J, Maurel P, Templin M, Gerbal-Chaloin S, Daujat-Chavanieu M
Drug Metab Dispos. 2018 Mar;46(3):223-236. doi: 10.1124/dmd.117.078683. Epub 2017 Dec 21.
2018
Zur Publikation
2018 |
Structure-dependent induction of apoptosis by hepatotoxic pyrrolizidine alkaloids in the human hepatoma cell line HepaRG: Single versus repeated exposure
Waizenegger J, Braeuning A, Templin M, Lampen A, Hessel-Pras S
Food Chem Toxicol. 2018 Apr;114:215-226. doi: 10.1016/j.fct.2018.02.036. Epub 2018 Feb 16.
2018
Zur Publikation
2018 |
Neurofascin Knock Down in the Basolateral Amygdala Mediates Resilience of Memory and Plasticity in the Dorsal Dentate Gyrus Under Stress
Saha R, Kriebel M, Volkmer H, Richter-Levin G, Albrecht A
Molecular Neurobiology. 2018 Sept; 55(9): 7317-7326. DOI: 10.1007/s12035-018-0930-2
2018
Zur Publikation
2018 |
Nanofluidic technology for chemical neurostimulation
Jones PD
Tübingen: Dissertation, Mathematisch-Naturwissenschaftliche Fakultät, Eberhard Karls Universität Tübingen, 2018. 129 Seiten.
2018
Zur Publikation
2018 |
Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates
Weiß F, Hammer HS, Klein K, Planatscher H, Zanger UM, Norén A, Wegler C, Artursson P, Joos TO, Poetz O
Drug Metab Dispos. 2018 Apr;46(4):387-396. doi: 10.1124/dmd.117.078626. Epub 2018 Jan 17.
2018
Zur Publikation
2018 |
Platelet protein biomarker panel for ovarian cancer diagnosis
Lomnytska M, Pinto R, Becker S, Engström U, Gustafsson S, Björklund C, Templin M, Bergstrand J, Xu L, Widengren J, Epstein E, Franzén B, Auer G.
Biomark Res. 2018 Jan 12;6:2. doi: 10.1186/s40364-018-0118-y.
2018
Zur Publikation
2018 |
Functional protein and pathway profiling of patient-derived tumor models for drug testing and precision medicine applications using Reverse Phase Protein Arrays (RPPA)
Gierke B, Bodenhofer M, Schmees C, Pawlak M
European Journal of Cancer. 2018 November 13-16; 103S1 (e21–e1489):e109
2018
Zur Publikation
2017 |
Investigation of the functional retinal output using Microelectrode arrays
Zeck G
Methods Mol Biol. 2018;1695:81-88. doi: 10.1007/978-1-4939-7407-8_8.
2017
Zur Publikation
2017 |
Electrophysiological Characterization of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for the Development of new in vitro Assays in Preclinical Cardiac Risk Assessment of Drugs
Küchler, S
Masterthesis, 2017; Brandenburgische Technische Universität Cottbus-Senftenberg.
2017
Zur Publikation
2017 |
The influence of mechanical stress during the differentiation on the electrophysiological properties of human embryonic stem cell – derived cardiomyocytes
Knolle, S
Masterthesis, 2017; Brandenburgische Technische Universität Cottbus-Senftenberg.
2017
Zur Publikation
2017 |
Perturbation of GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Induces Trans-regional Metaplasticity at the Medial Prefrontal Cortex
Saha R, Shrivastava K, Jing L, Schayek R, Maroun M, Kriebel M, Volkmer H, Richter-Levin G
Cereb Cortex. 2017 Nov; 9:1-16. doi: 10.1093/cercor/bhx300.
2017
Zur Publikation
2017 |
Development and Validation of an Ultrasensitive Procalcitonin Sandwich Immunoassay
Carcamo Yañez V, Göpfert J, Otto M, Tumani H, Peter A, Joos T
High-Throughput. 2017; 6(4): 18. https://doi.org/10.3390/ht6040018
2017
Zur Publikation
2017 |
Validation of HAV biomarker 2A for differential diagnostic of hepatitis A infected and vaccinated individuals using multiplex serology
Bohm K, Filomena A, Schneiderhan-Marra N, Krause G, Sievers C
Vaccine. 2017 Oct 13;35(43):5883-5889. doi: 10.1016/j.vaccine.2017.08.089. Epub 2017 Sep 14.
2017
Zur Publikation
2017 |
Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform
Filomena A, Guenther A, Planatscher H, Topin F, She J, Formichella L, Terradot L, Gerhard M, Joos TO, Meyer H, Schneiderhan-Marra N
Proteomes. 2017 Oct 3;5(4). pii: E24. doi: 10.3390/proteomes5040024.
2017
Zur Publikation
2017 |
Study of the Humoral Immune Response towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay
Filomena A, Göpfert JC, Duffy D, Pol S, Abdel-Hamid M, Esmat G, Fontanet A, Albert M, Joos T, Schneiderhan-Marra N
High-Throughput. 2017; 6(4): 15.
2017
Zur Publikation
2017 |
Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori
Filomena A, Pessler F, Akmatov M, Krause G, Duffy D, Gärtner B, Gerhard M, Albert M, Joos T, Schneiderhan-Marra N,
High-Throughput. 2017; 6(4): 14.
2017
Zur Publikation
2017 |
Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells
Toulany M, Maier J, Iida M, Rebholz S, Holler M, Grottke A, Jüker M, Wheeler DL, Rothbauer U, Rodemann HP
Cell Death Discovery. 2017; 3:17072
2017
Zur Publikation
2017 |
Tau plasma levels in subjective cognitive decline: Results from the DELCODE study
Muller S, Preische O, Gopfert JC, Yanez VAC, Joos TO, Boecker H, Duzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, Peters O, Menne F, Schipke CG, Schneider A, Spottke A, Fliessbach K, Kilimann I, Teipel S, Wagner M, Wiltfang J, Jessen F, Laske C
Sci Rep. 2017 Aug 25;7(1):9529. doi: 10.1038/s41598-017-08779-0.
2017
Zur Publikation
2017 |
Development and clinical testing of individual immunoassays for the quantification of serum glycoproteins to diagnose prostate cancer
Endt K, Goepfert J, Omlin A, Athanasiou A, Tennstedt P, Guenther A, Rainisio M, Engeler DS, Steuber T, Gillessen S, Joos T, Schiess R
PLoS One. 2017 Aug 2;12(8):e0181557. doi: 10.1371/journal.pone.0181557. eCollection 2017.
2017
Zur Publikation
2017 |
Under the Microscope: Single-Domain Antibodies for Live-Cell Imaging and Super-Resolution Microscopy
Traenkle B, Rothbauer U
Front Immunol. 2017 Aug 24;8:1030. doi: 10.3389/fimmu.2017.01030. eCollection 2017.
2017
Zur Publikation
2017 |
Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies
Seibel R, Maier S, Schnellbaecher A, Bohl S, Wehsling M, Zeck A, Zimmer A
MAbs. 2017 Aug/Sep;9(6):889-897. doi: 10.1080/19420862.2017.1333212. Epub 2017 Jun 5.
2017
Zur Publikation
2017 |
Impact of serum and dialysates obtained from chronic hemodialysis patients maintained on high cut-off membranes on inflammation profile in human THP-1 monocytes
Trojanowicz B, Ulrich C, Fiedler R, Storr M, Boehler T, Martus P, Pawlak M, Glomb MA, Henning C, Templin M, Werner K, Zickler D, Willy K, Schindler R, Girndt M
Hemodial Int. 2017 Jul;21(3):348-358. doi: 10.1111/hdi.12494. Epub 2016 Sep 26.
2017
Zur Publikation
2017 |
Reverse Phase Protein Arrays elucidate mechanisms-of-action and phenotypic response in 2D and 3D models
Pawlak M, Carragher NO (2017)
Drug Discov Today Technol. 2017 Mar;23:7-16. doi: 10.1016/j.ddtec.2017.05.002. Epub 2017 May 30.
2017
Zur Publikation
2017 |
Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition
Schelle J, Hasler LM, Gopfert JC, Joos TO, Vanderstichele H, Stoops E, Mandelkow EM, Neumann U, Shimshek DR, Staufenbiel M, Jucker M, Kaeser SA
Alzheimers Dement. 2017 Jun;13(6):701-709. doi: 10.1016/j.jalz.2016.09.005. Epub 2016 Oct 14.
2017
Zur Publikation
2017 |
GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Projection Neurons Modulate Fear Extinction
Saha R, Knapp S, Chakraborty D, Horovitz O, Albrecht A, Kriebel M, Kaphzan H, Ehrlich I, Volkmer H, Richter-Levin G
Neuropsychopharmacology. 2017 Jan;42(2):473-484. doi: 10.1038/npp.2016.205. Epub 2016 Sep 16.
2017
Zur Publikation
2017 |
Steps toward Maturation of Embryonic Stem Cell-Derived Cardiomyocytes by Defined Physical Signals
Shen N, Knopf A, Westendorf C, Kraushaar U, Riedl J, Bauer H, Poschel S, Layland SL, Holeiter M, Knolle S, Brauchle E, Nsair A, Hinderer S, Schenke-Layland K
Stem Cell Reports. 2017 Jul 11;9(1):122-135. doi: 10.1016/j.stemcr.2017.04.021. Epub 2017 May 18.
2017
Zur Publikation
2017 |
Pharmacodynamics of Oxaliplatin-Derived Platinum Compounds During Hyperthermic Intraperitoneal Chemotherapy (HIPEC): An Emerging Aspect Supporting the Rational Design of Treatment Protocols
Loffler MW, Schuster H, Zeck A, Quilitz N, Weinreich J, Tolios A, Haen SP, Horvath P, Lob S, Rammensee HG, Konigsrainer I, Konigsrainer A, Beckert S
Ann Surg Oncol. 2017 Jun;24(6):1650-1657. doi: 10.1245/s10434-017-5790-x. Epub 2017 Feb 3.
2017
Zur Publikation
2017 |
Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease
Brockmann K, Schulte C, Schneiderhan-Marra N, Apel A, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Bernard A, Gasser T, Marras C, Schule B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Berg D, Maetzler W
Eur J Neurol. 2017 Feb;24(2):427-e6. doi: 10.1111/ene.13223.
2017
Zur Publikation
2017 |
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice
Marx-Stoelting P, Ganzenberg K, Knebel C, Schmidt F, Rieke S, Hammer H, Schmidt F, Potz O, Schwarz M, Braeuning A
Arch Toxicol. 2017 Aug;91(8):2895-2907. doi: 10.1007/s00204-016-1925-2. Epub 2017 Jan 6.
2017
Zur Publikation
2017 |
Innate immune system favors emergency monopoiesis at the expense of DC-differentiation to control systemic bacterial infection in mice
Pasquevich KA, Bieber K, Gunter M, Grauer M, Potz O, Schleicher U, Biedermann T, Beer-Hammer S, Buhring HJ, Rammensee HG, Zender L, Autenrieth IB, Lengerke C, Autenrieth SE
Eur J Immunol. 2015 Oct;45(10):2821-33. doi: 10.1002/eji.201545530. Epub 2015 Jul 24.
2017
Zur Publikation
2017 |
Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition
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Blood. 2017 Jan 12;129(2):e1-e12. doi: 10.1182/blood-2016-05-714048. Epub 2016 Nov 9.
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Addressing Functional Neurotoxicity Using the Microelectrode Array (MEA)
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Stem Cell-Derived Models in Toxicology. M. Clements and L. Roquemore. New York, NY: Springer New York; 2017. 293-309.
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Medium Cut-Off (MCO) Membranes Reduce Inflammation in Chronic Dialysis Patients-A Randomized Controlled Clinical Trial
Zickler D, Schindler R, Willy K, Martus P, Pawlak M, Storr M, Hulko M, Boehler T, Glomb MA, Liehr K, Henning C, Templin M, Trojanowicz B, Ulrich C, Werner K, Fiedler R, Girndt M
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A Nexus Consisting of Beta-Catenin and Stat3 Attenuates BRAF Inhibitor Efficacy and Mediates Acquired Resistance to Vemurafenib
Sinnberg T, Makino E, Krueger MA, Velic A, Macek B, Rothbauer U, Groll N, Potz O, Czemmel S, Niessner H, Meier F, Ikenberg K, Garbe C, Schittek B
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Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
Kempf H, Olmer R, Haase A, Franke A, Bolesani E, Schwanke K, Robles-Diaz D, Coffee M, Gohring G, Drager G, Potz O, Joos T, Martinez-Hackert E, Haverich A, Buettner FF, Martin U, Zweigerdt R
Nat Commun. 2016 Dec 9;7:13602. doi: 10.1038/ncomms13602.
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Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition
Schelle J, Hasler L, Gopfert JC, Joos TO, Vanderstichele H, Stoops E, Mandelkow EM, Neumann U, Shimshek DR, Staufenbiel M, Jucker M, Kaeser SA
Alzheimers Dement. 2017 Jun;13(6):701-709. doi: 10.1016/j.jalz.2016.09.005. Epub 2016 Oct 14.
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Plasma matrix metalloproteinase 2 levels and breast cancer risk
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Cancer Epidemiol. 2015 Jun;39(3):321-7. doi: 10.1016/j.canep.2015.02.010. Epub 2015 Mar 19.
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Selective p38alpha MAP kinase/MAPK14 inhibition in enzymatically-modified LDL-stimulated human monocytes: implications for atherosclerosis
Cheng F, Twardowski L, Fehr S, Aner C, Schaeffeler E, Joos T, Knorpp T, Dorweiler B, Laufer S, Schwab M, Torzewski M
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Coordinate regulation of Cyp2e1 by beta-catenin- and hepatocyte nuclear factor 1alpha-dependent signaling
Groll N, Petrikat T, Vetter S, Colnot S, Weiss F, Poetz O, Joos TO, Rothbauer U, Schwarz M, Braeuning A
Toxicology. 2016 Mar 28;350-352:40-8. doi: 10.1016/j.tox.2016.05.004. Epub 2016 May 3.
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Coordinating Role of RXRalpha in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling
Keller R, Klein M, Thomas M, Drager A, Metzger U, Templin MF, Joos TO, Thasler WE, Zell A, Zanger UM
PLoS Comput Biol. 2016 Jan 4;12(1):e1004431. doi: 10.1371/journal.pcbi.1004431. eCollection 2016 Jan.
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Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single-Use Stirred Tank Bioreactors
Kropp C, Kempf H, Halloin C, Robles-Diaz D, Franke A, Scheper T, Kinast K, Knorpp T, Joos TO, Haverich A, Martin U, Zweigerdt R, Olmer R
Stem Cells Transl Med. 2016 Oct;5(10):1289-1301. Epub 2016 Jul 1.
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Evaluation of novel biomarkers of nephrotoxicity in Cynomolgus monkeys treated with gentamicin
Gautier JC, Zhou X, Yang Y, Gury T, Qu Z, Palazzi X, Leonard JF, Slaoui M, Veeranagouda Y, Guizon I, Boitier E, Filali-Ansary A, van den Berg BH, Poetz O, Joos T, Zhang T, Wang J, Detilleux P, Li B
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Inhibition of beta-catenin signaling by phenobarbital in hepatoma cells in vitro
Groll N, Petrikat T, Vetter S, Wenz C, Dengjel J, Gretzmeier C, Weiss F, Poetz O, Joos TO, Schwarz M, Braeuning A
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Role of BCL9L in transforming growth factor-beta (TGF-beta)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer
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GABAergic Synapses at the Axon Initial Segment of Basolateral Amygdala Projection Neurons Modulate Fear Extinction
Saha R, Knapp S, Chakraborty D, Horovitz O, Albrecht A, Kriebel M, Kaphzan H, Ehrlich I, Volkmer H, Richter-Levin G
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Nachrichten aus der Chemie. 2016; 64(7-8): 758-760.
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Doktorarbeit, Medizinische Fakultät, Eberhard Karls Universität Tübingen. 2016. 118 Seiten.
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Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection
Rast G, Kraushaar U, Buckenmaier S, Ittrich C, Guth BD
J Pharmacol Toxicol Methods. 2016 Nov - Dec;82:74-82. doi: 10.1016/j.vascn.2016.08.002. Epub 2016 Aug 9.
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Introduction to polymer-based solid-contact ion-selective electrodes-basic concepts, practical considerations, and current research topics
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Anal Bioanal Chem. 2017 Jan;409(1):45-61. doi: 10.1007/s00216-016-9945-6. Epub 2016 Oct 1.
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J Neurophysiol. 2016 Oct 1;116(4):1684-1693. doi: 10.1152/jn.01095.2015. Epub 2016 Jul 13.
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J Neurosci Methods. 2016 Sep 15;271:1-13. doi: 10.1016/j.jneumeth.2016.06.006. Epub 2016 Jun 15.
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Electrochemical noise and impedance of Au electrode/electrolyte interfaces enabling extracellular detection of glioma cell populations
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Visualizing Epithelial-Mesenchymal Transition Using the Chromobody Technology
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Influence of field potential duration on spontaneous beating rate of human induced pluripotent stem cell-derived cardiomyocytes: Implications for data analysis and test system selection.
Rast G, Kraushaar U, Buckenmaier S, Ittrich C, Guth BD
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Proteomics Clin Appl. 2016 Oct;10(9-10):1049-1057. doi: 10.1002/prca.201600033. Epub 2016 Aug 3.
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Entwicklung eines multiplexen HBV Assays zur Unterscheidung von geimpften und natürlich infizierten Personen
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Receptor tyrosine kinase EphA7 is required for interneuron connectivity at specific subcellular compartments of granule cells
Beuter S, Ardi Z, Horovitz O, Wuchter J, Keller S, Saha R, Tripathi K, Anunu R, Kehat O, Kriebel M, Richter-Levin G, Volkmer H
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Brockmann K, Apel A, Schulte C, Schneiderhan-Marra N, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Gasser T, Schule B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Marras C, Berg D, Maetzler W
J Neuroinflammation. 2016 May 24;13(1):122. doi: 10.1186/s12974-016-0588-5.
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Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury
Mikus M, Drobin K, Gry M, Bachmann J, Lindberg J, Yimer G, Aklillu E, Makonnen E, Aderaye G, Roach J, Fier I, Kampf C, Gopfert J, Perazzo H, Poynard T, Stephens C, Andrade RJ, Lucena MI, Arber N, Uhlen M, Watkins PB, Schwenk JM, Nilsson P, Schuppe-Koistinen I
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Expanding an efficient, electrically driven and CNT-tagged P450 system into the third dimension: a nanowired CNT containing and enzyme stabilising 3D sol-gel electrode
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Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approaches
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From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38 MAPK Inhibitors
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Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society
Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB, Nishizuka SS, Pawlak M, Petricoin EF 3rd, Pollard HB, Serrels B, Zhu J
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Alternative splicing of MALT1 controls signalling and activation of CD4(+) T cells
Meininger I, Griesbach RA, Hu D, Gehring T, Seeholzer T, Bertossi A, Kranich J, Oeckinghaus A, Eitelhuber AC, Greczmiel U, Gewies A, Schmidt-Supprian M, Ruland J, Brocker T, Heissmeyer V, Heyd F, Krappmann D
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Evaluation of Protein Profiles From Treated Xenograft Tumor Models Identifies an Antibody Panel for Formalin-fixed and Paraffin-embedded (FFPE) Tissue Analysis by Reverse Phase Protein Arrays (RPPA)
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A Multiplexed High-Content Screening Approach Using the Chromobody Technology to Identify Cell Cycle Modulators in Living Cells
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J Biomol Screen. 2016 Oct;21(9):965-77. doi: 10.1177/1087057116641935. Epub 2016 Apr 4.
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A New Nanobody-Based Biosensor to Study Endogenous PARP1 In Vitro and in Live Human Cells
Buchfellner A, Yurlova L, Nuske S, Scholz AM, Bogner J, Ruf B, Zolghadr K, Drexler SE, Drexler GA., Girst S, Greubel C, Reindl J, Siebenwirth C, Romer T, Friedl AA, Rothbauer U
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Catch and Patch: A Pipette-Based Approach for Automating Patch Clamp That Enables Cell Selection and Fast Compound Application
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Assay Drug Dev Technol. 2016 Mar;14(2):144-55. doi: 10.1089/adt.2015.696.
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PLAC8 Localizes to the Inner Plasma Membrane of Pancreatic Cancer Cells and Regulates Cell Growth and Disease Progression through Critical Cell-Cycle Regulatory Pathways
Kaistha BP, Lorenz H, Schmidt H, Sipos B, Pawlak M, Gierke B, Kreider R, Lankat-Buttgereit B, Sauer M, Fiedler L, Krattenmacher A, Geisel B, Kraus JM, Frese KK, Kelkenberg S, Giese NA, Kestler HA, Gress TM, Buchholz M
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Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia
Schultheiss M, Schnichels S, Hermann T, Hurst J, Feldkaemper M, Arango-Gonzalez B, Ueffing M, Bartz-Schmidt KU, Zeck G, Spitzer MS
PLoS One. 2016 Feb 5;11(2):e0148616. doi: 10.1371/journal.pone.0148616. eCollection 2016.
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MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors
Oroszlan G, Kortvely E, Szakacs D, Kocsis A, Dammeier S, Zeck A, Ueffing M, Zavodszky P, Pal G, Gal P, Dobo J
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Pre-Analytical Parameters Affecting Vascular Endothelial Growth Factor Measurement in Plasma: Identifying Confounders
Walz JM, Boehringer D, Deissler HL, Faerber L, Goepfert JC, Heiduschka P, Kleeberger SM, Klettner A, Krohne TU, Schneiderhan-Marra N, Ziemssen F, Stahl A
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A bead-based western for high-throughput cellular signal transduction analyses
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Peptides in headlock - a novel high-affinity and versatile peptide-binding nanobody for proteomics and microscopy
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Phenobarbital inhibits calpain activity and expression in mouse hepatoma cells
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Biol Chem. 2016 Jan 1;397(1):91-6. doi: 10.1515/hsz-2015-0223.
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Selective, efficient modulation of activated CD4+ alphabetaT cells by the novel humanized antibody GZ-alphabetaTCR targeting human alphabetaTCR
Blank G, Welker C, Haarer J, Sterk M, Nadalin S, Yanez VA, Joos TO, Menrad A, Snell D, LaCorcia G, Konigsrainer A, Handgretinger R, Schilbach K
Bone Marrow Transplant. 2015 Mar;50(3):390-401. doi: 10.1038/bmt.2014.263. Epub 2014 Nov 17.
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Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells
Brun J, Lutz KA, Neumayer KM, Klein G, Seeger T, Uynuk-Ool T, Worgotter K, Schmid S, Kraushaar U, Guenther E, Rolauffs B, Aicher WK, Hart ML
PLoS One. 2015 Dec 16;10(12):e0145153. doi: 10.1371/journal.pone.0145153. eCollection 2015.
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EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
Schneck H, Gierke B, Uppenkamp F, Behrens B, Niederacher D, Stoecklein NH, Templin MF, Pawlak M, Fehm T, Neubauer H
PLoS One. 2015 Dec 22;10(12):e0144535. doi: 10.1371/journal.pone.0144535. eCollection 2015.
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miR-124 disinhibits neurite outgrowth in an inflammatory environment
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Cell Tissue Res. 2015 Oct;362(1):9-20. doi: 10.1007/s00441-015-2183-y. Epub 2015 Apr 29.
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Immunoliposomes for Targeted Delivery of an Antifibrotic Drug
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Mol Pharm. 2015 Sep 8;12(9):3146-57. doi: 10.1021/acs.molpharmaceut.5b00012. Epub 2015 Jul 28.
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Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies
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Immunoliposomes for Targeted Delivery of an Antifibrotic Drug
Schuster L, Seifert, O, Vollmer S, Kontermann RE, Schlosshauer B, Hartmann H
Mol Pharm. 2015 Sep 8;12(9):3146-57. doi: 10.1021/acs.molpharmaceut.5b00012. Epub 2015 Jul 28.
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Evaluation of protein profiles from treated xenograft tumor models identifies an antibody panel for FFPE tissue analysis by reverse phase protein arrays
Bader S, Zajac M, Friess T, Ruge E, Rieder N, Gierke B, Heubach Y, Thomas M, Pawlak M
Mol Cell Proteomics. 2015 Oct;14(10):2775-85. doi: 10.1074/mcp.O114.045542. Epub 2015 Jun 23.
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Live imaging of endogenous protein dynamics in zebrafish using chromobodies.
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Development. 2015 May 15;142(10):1879-84. doi: 10.1242/dev.118943.
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Monitoring interactions and dynamics of endogenous beta-catenin with intracellular nanobodies in living cells
Traenkle B, Emele F, Anton R, Poetz O, Haeussler RS, Maier J, Kaiser PD, Scholz AM, Nueske S, Buchfellner A, Romer T, Rothbauer U
Mol Cell Proteomics. 2015 Mar;14(3):707-23. doi: 10.1074/mcp.M114.044016. Epub 2015 Jan 16.
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Generation of an alpaca-derived nanobody recognizing gamma-H2AX
Rajan M, Mortusewicz O, Rothbauer U, Hastert FD, Schmidthals K, Rapp A, Leonhardt H, Cardoso MC
FEBS Open Bio. 2015 Sep 21;5:779-88. doi: 10.1016/j.fob.2015.09.005. eCollection 2015.
2015
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2015 |
A Bead-Based Multiplex Sandwich Immunoassay to Assess the Abundance and Posttranslational Modification State of beta-Catenin
Groll N, Sommersdorf C, Joos TO, Poetz O
Methods Mol Biol. 2015;1295:441-53. doi: 10.1007/978-1-4939-2550-6_31.
2015
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2015 |
Human placenta-derived CD146-positive mesenchymal stromal cells display a distinct osteogenic differentiation potential
Ulrich C, Abruzzese T, Maerz JK, Ruh M, Amend B, Benz K, Rolauffs B, Abele H, Hart ML, Aicher WK
Stem Cells Dev. 2015 Jul 1;24(13):1558-69. doi: 10.1089/scd.2014.0465. Epub 2015 Apr 13.
2015
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2015 |
Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry
Weiß F, Schnabel A, Planatscher H, van den Berg BHJ, Serschnitzki B, Nuessler AK, Thasler WE, Weiss TS, Reuss M, Stoll D, Templin MF, Joos TO, Marcus K, Poetz O
Sci Rep. 2015 Mar 4;5:8759. doi: 10.1038/srep08759.
2015
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2015 |
Towards multiplexed protein-protein interaction analysis using protein tag-specific nanobodies
Groll N, Emele F, Poetz O, Rothbauer U
J Proteomics. 2015 Sep 8;127(Pt B):289-99. doi: 10.1016/j.jprot.2015.04.017. Epub 2015 May 1.
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Bead-Based Peptide Arrays for Profiling the Specificity of Modification State-Specific Antibodies
Filomena A, Beiter Y, Templin MF, Joos TO, Schneiderhan-Marra N, Poetz O
Methods Mol Biol. 2015;1348:251-65. doi: 10.1007/978-1-4939-2999-3_22.
2015
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2015 |
PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities
Samba R, Herrmann T, Zeck G
J Neural Eng. 2015 Feb;12(1):016014. doi: 10.1088/1741-2560/12/1/016014. Epub 2015 Jan 14.
2015
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Daylight vision repair by cell transplantation
Santos-Ferreira T, Postel K, Stutzki H, Kurth T, Zeck G, Ader M
Stem Cells. 2015 Jan; 33(1):79-90. doi: 10.1002/stem.1824.
2015
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2014 |
Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [18F] FDG-PET imaging combined with proteomic approaches
Tegnebratt T, Ruge E, Bader S, Ishii N, Aida S, Yoshimura Y, Ooi C-H, Lu L, Mitsios N, Meresse V, Mulder J, Pawlak M, Venturi M, Tessier J, Stone-Elander S
EJNMMI Res. 2014 Dec;4(1):34. doi: 10.1186/s13550-014-0034-6. Epub 2014 Sep 9.
2014
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2014 |
Plasma matrix metalloproteinase 1, 3, and 7 levels and breast cancer risk in the Nurses' Health study
Aroner SA, Rosner BA, Tamimi RM, Tworoger SS, Baur N, Joos TO, Hankinson SE
Cancer Causes Control. 2014 Dec;25(12):1717-23. doi: 10.1007/s10552-014-0462-7. Epub 2014 Sep 16.
2014
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Dentate Gyrus Local Circuit is Implicated in Learning Under Stress-a Role for Neurofascin
Zitman FM, Lucas M, Trinks S, Grosse-Ophoff L, Kriebel M, Volkmer H, Richter-Levin G
Mol Neurobiol (2016) 53:842–850 DOI 10.1007/s12035-014-9044-7
2014
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2014 |
Key role of dual specificity kinase TTK in proliferation and survival of pancreatic cancer cells
Kaistha BP, Honstein T, Muller V, Bielak S, Sauer M, Kreider R, Fassan M, Scarpa A, Schmees C, Volkmer H, Gress TM, Buchholz, M
Br J Cancer. 2014 Oct 28;111(9):1780-7. doi: 10.1038/bjc.2014.460. Epub 2014 Aug 19.
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Towards plug and play filling of microfluidic devices by utilizing networks of capillary stop valves
Hagmeyer B, Zechnall F, Stelzle M
Biomicrofluidics. 2014 Sep 19;8(5):056501. doi: 10.1063/1.4896063. eCollection 2014 Sep.
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2014 |
Rhythmic Ganglion Cell Activity in Bleached and Blind Adult Mouse Retinas
Menzler J, Channappa L, Zeck G
PLoS One. 2014 Aug 25;9(8):e106047. doi: 10.1371/journal.pone.0106047. eCollection 2014.
2014
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2014 |
Realizing the Promise of Reverse Phase Protein Arrays for Clinical, Translational, and Basic Research: A Workshop Report: The RPPA (Reverse Phase Protein Array) Society
Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB, Nishizuka SS, Pawlak M, Petricoin EF, Pollard HB, Serrels B, Zhu J
Mol Cell Proteomics. 2014 Jul;13(7):1625-43. doi: 10.1074/mcp.O113.034918. Epub 2014 Apr 28.
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Polyelectrolyte multilayers as functional coatings for controlled biomolecular interactions
Hartmann H, Schlosshauer B
In: Biofunctional Surface Engineering. M. Scholz (Ed), Pan Stanford Publishing 2014: 27-46.
2014
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Stress modulation of hippocampal activity - Spotlight on the dentate gyrus
Fa M, Xia L, Anunu R, Kehat O, Kriebel M, Volkmer H, Richter-Levin G
Neurobiol Learn Mem. 2014 Jul;112C:53-60. doi: 10.1016/j.nlm.2014.04.008. Epub 2014 Apr 18.
2014
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Isolation, expansion and transplantation of postnatal murine progenitor cells of the enteric nervous system
Dettmann HM, Zhang Y, Wronna N, Kraushaar U, Guenther E, Mohr R, Neckel PH, Mack A, Fuchs J, Just L, Obermayr F
PLoS One. 2014 May 28;9(5):e97792. doi: 10.1371/journal.pone.0097792. eCollection 2014.
2014
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A p38 substrate-specific MK2-EGFP translocation assay for identification and validation of new p38 inhibitors in living cells: a comprising alternative for acquisition of cellular p38 inhibition data
Anton R, Bauer SM, Keck PR, Laufer S, Rothbauer U
PLoS One. 2014 Apr 17;9(4):e95641. doi: 10.1371/journal.pone.0095641. eCollection 2014.
2014
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2014 |
Cross-platform toxicogenomics for the prediction of non-genotoxic hepatocarcinogenesis in rat
Romer M, Eichner J, Metzger U, Templin MF, Plummer S, Ellinger-Ziegelbauer H, Zell A
PLoS One. 2014 May 15;9(5):e97640. doi: 10.1371/journal.pone.0097640. eCollection 2014.
2014
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2014 |
Recent progress in generating intracellular functional antibody fragments to target and trace cellular components in living cells
Kaiser PD, Maier J, Traenkle B, Emele F, Rothbauer U
Biochim Biophys Acta. 2014 Nov;1844(11):1933-1942. doi: 10.1016/j.bbapap.2014.04.019. Epub 2014 May 2.
2014
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Organ-Like Cell Cultures in Microfluidic Systems
Li D, Schütte J, Stelzle M
2015 in: Li D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, New York, NY.
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Action potentials in retinal ganglion cells are initiated at the site of maximal curvature of the extracellular potential
Eickenscheidt M, Zeck G
J Neural Eng. 2014 Jun;11(3):036006. doi: 10.1088/1741-2560/11/3/036006. Epub 2014 Apr 24.
2014
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2014 |
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs
Gustems M, Woellmer A, Rothbauer U, Eck SH, Wieland T, Lutter D, Hammerschmidt W
Nucleic Acids Res. 2014 Mar;42(5):3059-72. doi: 10.1093/nar/gkt1323. Epub 2013 Dec 25.
2014
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2014 |
The Fluorescent Two-Hybrid Assay to Screen for Protein-Protein Interaction Inhibitors in Live Cells: Targeting the Interaction of p53 with Mdm2 and Mdm4
Yurlova L, Derks M, Buchfellner A, Hickson I, Janssen M, Morrison D, Stansfield I, Brown CJ, Ghadessy FJ, Lane DP, Rothbauer U, Zolghadr K, Krausz E
J Biomol Screen. 2014 Apr;19(4):516-25. doi: 10.1177/1087057113518067. Epub 2014 Jan 29.
2014
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A versatile assay for RNA-binding proteins in living cells
Strein C, Alleaume AM, Rothbauer U, Hentze MW, Castello A
RNA. 2014 May;20(5):721-31. doi: 10.1261/rna.043562.113. Epub 2014 Mar 24.
2014
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2014 |
Long-term culture and functionality of pancreatic islets monitored using microelectrode arrays
Schonecker S, Kraushaar U, Dufer M, Sahr A, Hardtner C, Guenther E, Walther R, Lendeckel U, Barthlen W, Krippeit-Drews P, Drews G
Integr Biol (Camb). 2014 Mar 24; 2014(4):540-544
2014
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2014 |
Application of PEDOT-CNT Microelectrodes for Neurotransmitter Sensing
Samba R, Fuchsberger K, Matiychyn I, Epple S, Kiesel L, Stett A, Schuhmann W, Stelzle M
Electroanalysis. 2014 March; 26(3): 548-555. https://doi.org/10.1002/elan.201300547
2014
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2014 |
Ha-ras and β-Catenin oncoproteins orchestrate metabolic programs in mouse liver tumors
Unterberger EB, Eichner J, Wrzodek C, Lempiäinen H, Luisier R, Terranova R, Metzger U, Plummer S, Knorpp T, Braeuning A, Moggs J, Templin MF, Honndorf V, Piotto M, Zell A, Schwarz M
International Journal of Cancer. 2014 Oct 1; 135(7): 1574-1585. https://doi.org/10.1002/ijc.28798
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Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury
Stutzki H, Leibig C, Andreadaki A, Fischer D, Zeck G
Front Cell Neurosci. 2014; 8: 38. doi: 10.3389/fncel.2014.00038
2014
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2014 |
Cell-type specific four-component hydrogel
Aberle T, Franke K, Rist E, Benz K, Schlosshauer B
PLoS One. 2014 Jan 27;9(1):e86740. doi: 10.1371/journal.pone.0086740. eCollection 2014.
2014
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2014 |
A touch of glue to complete bacteriophage assembly: the Tail-to-Head Joining Protein (THJP) family
Auzat I, Petitpas I, Lurz R, Weise F, Tavares P
Mol Microbiol. 2014 Jan 21;91(6): 1164-1178. doi: 10.1111/mmi.12526.
2014
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Identification of short terminal motifs enriched by antibodies using peptide mass fingerprinting
Planatscher H, Weiss F, Eisen D, Zell A, Joos T, Poetz O
Bioinformatics. 2014 May 1;30(9):1205-13. doi: 10.1093/bioinformatics/btu009. Epub 2014 Jan 9.
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Organisation and Control of Neuronal Connectivity and Myelination by Cell Adhesion Molecule Neurofascin
Ebel J, Beuter S, Wuchter J, Kriebel M, Volkmer H
2014. in: Berezin V, Walmod P (eds). Cell Adhesion Molecules. Advances in Neurobiology, Springer New York. 8: 231-247
2013
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A New In Vitro Model to Study Cellular Responses after Thermomechanical Damage in Monolayer Cultures
Hettler A, Werner S, Eick S, Laufer S, Weise F
PLoS One. 2013; 8(12): e82635. doi: 10.1371/journal.pone.0082635
2013
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Development of a novel assay for proprotein converting enzyme activity on a multiplex bead-based array system
Albrecht A, Rahmoune H, Leedjarv K, Knorpp T, Joos T, Stocki P, Guest PC, Bahn S
Proteomics. 2013 Oct;13(20):2976-9. doi: 10.1002/pmic.201300060.
2013
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Catch and measure-mass spectrometry-based immunoassays in biomarker research
Weiss F, van den Berg BH, Planatscher H, Pynn CJ, Joos TO, Poetz O
Biochim Biophys Acta. 2014 May; 1844(5);927-932. doi: 10.1016/j.bbapap.2013.09.010.
2013
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Multiple Protein Analysis of Formalin-fixed and Paraffin-embedded Tissue Samples with Reverse phase Protein Arrays
Assadi M, Lamerz J, Jarutat T, Farfsing A, Paul H, Gierke B, Breitinger E, Templin MF, Essioux L, Arbogast S, Venturi M, Pawlak M, Langen H, Schindler T
Mol Cell Proteomics. 2013 Sep;12(9):2615-22. doi: 10.1074/mcp.M112.023051. Epub 2013 May 7.
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Label-free detection of tumor markers in a colon carcinoma tumor progression model by confocal Raman microspectroscopy
Scalfi-Happ C, Rück A, Udart M, Hauser C, Dürr C, Kriebel M
Proc. SPIE. Clinical and Biomedical Spectroscopy and Imaging III. 2013 June 18; 87980B. doi:10.1117/12.2032459;
2013
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2013 |
Adhesion to Extracellular Matrix Proteins can Differentiate Between Human Bone Marrow Derived Mesenchymal Stem Cells and Fibroblasts
Roncoroni LP, Maerz JK, Angres B, Steuer H, Benz K, Abruzzese T, Hart ML, Rolauffs B, Klein G, Stoll D, Aicher WK
J Tissue Sci Eng. 2012;3:3. doi: 10.4172/2157-7552.S1.003
2013
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In vivo single branch axotomy induces GAP-43–dependent sprouting and synaptic remodeling in cerebellar cortex
Allegra Mascaroa AL, Cesare P, Sacconia L, Grasselli G, Mandolesi G, Maco BL, Knott GW, Huang L, De Paola V, Strata P, Pavone FS
PNAroc Natl Acad Sci U S A. 2013 Jun 25; 110(26): 10824–10829. doi: 10.1073/pnas.1219256110
2013
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Cell-Based Therapy for the Deficient Urinary Sphincter
Hart ML, Neumayer KMH, Vaegler M, Daum L, Amend B, Sievert KD, Di Giovanni S, Kraushaar U, Guenther E, Stenzl A, Aicher WK
Curr Urol Rep. 2013 Oct;14(5):476-87. doi: 10.1007/s11934-013-0352-7.
2013
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Maintenance of "stem cell" features of cartilage cell sub-populations during in vitro propagation
Benz K, Stippich C, Freudigmann C, Mollenhauer JA, Aicher WK
J Transl Med. 2013 Jan 30;11:27. doi: 10.1186/1479-5876-11-27.
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Multiple protein analysis of FFPE tissue samples with reverse-phase protein arrays
Assadi M, Lamerz J, Jarutat T, Farfsing A, Paul H, Gierke B, Breitinger E, Templin MF, Essioux L, Arbogast S, Venturi M, Pawlak M, Langen H, Schindler T
Mol Cell Proteomics. 2013 Sep;12(9):2615-22. doi: 10.1074/mcp.M112.023051. Epub 2013 May 7.
2013
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Regulation of Adhesion by Flexible Ectodomains of IgCAMs
Volkmer H, Schreiber J, Rathjen FG
Neurochem Res. 2013 Jun;38(6):1092-9. doi: 10.1007/s11064-012-0888-9. Epub 2012 Oct 9.
2013
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Hyaluronic acid / chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexes
Hartmann H, Hossfeld S, Schlosshauer B, Mittnacht U, Pego AP, Dauner M, Doser M, Stoll D, Krastev R
J Control Release. 2013 Apr 4;168(3):289-297. doi: 10.1016/j.jconrel.2013.03.026.
2013
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Prostate carcinoma cell growth-inhibiting hydrogel supports axonal regeneration in vitro
Franke K, Baur M, Daum L, Vaegler M, Sievert KD, Schlosshauer B
Neurosci Lett. 2013 Apr 29;541:248-52. doi: 10.1016/j.neulet.2013.01.057. Epub 2013 Feb 15.
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Axonale Leitungsgeschwindigkeiten in der Kaninchenretina gemessen mit Multitransistorarray
Thoma M
Diplomarbeit. Physik-Department, Technische Universität München. 2012. 61 Seiten.
2013
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From spots to beads-PTM-peptide bead arrays for the characterization of anti-histone antibodies
Heubach Y, Planatscher H, Sommersdorf C, Maisch D, Maier J, Joos TO, Templin MF, Poetz O
Proteomics. 2013 Mar;13(6):1010-5. doi: 10.1002/pmic.201200383.
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Molecularly imprinted conductive polymers for controlled trafficking of neurotransmitters at solid-liquid interfaces
Paul N, Muller M, Paul A, Guenther E, Lauermann I, Muller-Buschbaum P, Lux-Steiner Muh
Soft Matter. 2013; 9(4): 1364-1371. DOI 10.1039/C2SM26896E
2013
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Future strategies include pluripotent stem cell-derived cardiomyocytes
Hess D
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Is the Enhanced Adhesion of PEDOT Thin Films on Electrodes Due to Sulfur - Gold Interaction? - An XPS Study
Samba R, Chassé T, Stelzle M
The Open Surface Science Journal. 2013; 5: 17-20.
2013
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Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion
Lempiainen H, Couttet P, Bolognani F, Muller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, Brasa S, Kalteis M, Marcellin M, Giudicelli F, Braeuning A, Morawiec L, Zamurovic N, Langle U, Scheer N, Schubeler D, Goodman J, Chibout SD, Marlowe J, Theil D, Heard DJ, Grenet O, Zell A, Templin MF, Meehan RR, Wolf RC, Elcombe CR, Schwarz M, Moulin P, Terranova R, Moggs JG
Toxicol Sci. 2013 Feb;131(2):375-86. doi: 10.1093/toxsci/kfs303. Epub 2012 Oct 22.
2013
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Determination of antibody glycosylation by mass spectrometry
Jager C, Ferrara C, Umana P, Zeck A, Regula JT, Koll H
Methods Mol Biol. 2012;901:195-208. doi: 10.1007/978-1-61779-931-0_13.
2013
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Plasma levels of soluble glycoprotein VI (sGPVI) are associated with ischemic stroke
Wurster T, Poetz O, Stellos K, Kremmer E, Melms A, Schuster A, Nagel E, Joos T, Gawaz M, Bigalke B
Platelets. 2013;24(7):560-5. doi: 10.3109/09537104.2012.746455. Epub 2012 Dec 5.
2013
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2012 |
Concurrent epigenetic silencing of wnt/beta-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia
Moskalev EA, Luckert K, Vorobjev IA, Mastitsky SE, Gladkikh AA, Stephan A, Schrenk M, Kaplanov KD, Kalashnikova OB, Poets O, Joos TO, Hoheisel JD
BMC Cancer. 2012 Jun 6;12:213. doi: 10.1186/1471-2407-12-213.
2012
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The recombinant bifunctional protein alphaCD133-GPVI promotes repair of the infarcted myocardium in mice
Baumer Y, Leder C, Ziegler M, Schonberger T, Ochmann C, Perk A, Degen H, Schmid-Horch B, Elvers M, Munch G, Ungerer M, Schlosshauer B, Gawaz M
J Thromb Haemost. 2012 Jun;10(6):1152-64. doi: 10.1111/j.1538-7836.2012.04710.x.
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CVD-Synthese von Kohlenstoff-Nanoröhren zur Nutzung als Mikroelektroden für neuronale Anwendungen
Stamm B, Schneider K, Herrmann T, Burkhardt C, Nisch W, Fleischer M, Kern DP, Stett A
WOMag, 2012 Nov: 14-17.
2012
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Low level sequence variant analysis of recombinant proteins: an optimized approach
Zeck A, Regula JT, Larraillet V, Mautz B, Popp O, Gopfert U, Wiegeshoff F, Vollertsen UE, Gorr IH, Koll H, Papadimitriou A
PLoS One. 2012;7(7):e40328. Epub 2012 Jul 6.
2012
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Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood
Schmohl M, Schneiderhan-Marra N, Baur N, Hefner K, Blum M, Stein GM, Joos TO, Schmolz M
Int Immunopharmacol. 2012 Oct 24;14(4):722-728. doi: 10.1016/j.intimp.2012.10.010.
2012
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Rezeptortyrosinkinasen regulieren die Oberflächenaggregation des neuronalen Gerüstproteins Gephyrin
Wuchter J
Doktorarbeit, Mathematisch-Naturwissenschaftliche Fakultät, Eberhard Karls Universität Tübingen. 2012. 133 Seiten.
2012
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2012 |
Combining ultracentrifugation and peptide termini group-specific immunoprecipitation for multiplex plasma protein analysis
Volk S, Schreiber TD, Eisen D, Wiese C, Planatscher H, Pynn CJ, Stoll D, Templin MF, Joos TO, Poetz O
Mol Cell Proteomics. 2012 Jul;11(7):O111.015438. Epub 2012 Apr 23.
2012
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A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins
Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, Macbeat G, Poetz O
Sci Signal. 2012 Jan 10;5(206):pl1. doi: 10.1126/scisignal.2002372.
2012
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A Comprehensive Small Interfering RNA Screen Identifies Signaling Pathways Required for Gephyrin Clustering
Wuchter J, Beuter S, Treindl F, Herrmann T, Zeck G, Templin MF, Volkmer H
The Journal of Neuroscience. 2012 Oct 17; 32(42):14821–14834
2012
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Electrical stimulation of retinal neurons in epiretinal and subretinal configuration using a multicapacitor array
Eickenscheidt M, Jenkner M, Thewes R, Fromherz P, Zeck G
J Neurophysiol. 2012 May;107(10):2742-55. Epub 2012 Feb 22.
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Conditional Disruption of Axin1 Leads to Development of Liver Tumors in Mice
Feng GJ, Cotta W, Wei XQ, Poetz O, Evans R, Jarde T, Reed K, Meniel V, Williams GT, Clarke AR, Dale TC
Gastroenterologie. 2012;143:1650–1659. http://dx.doi.org/10.1053/j.gastro.2012.08.047
2012
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2012 |
Identification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors
Bauer M, Chicca A, Tamborrini M, Eisen D, Lerner R, Lutz B, Poetz O, Pluschke G, Gertsch J
J Biol Chem. 2012 Oct 26; 287(44): 36944–36967. doi: 10.1074/jbc.M112.382481
2012
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Mycobacterium tuberculosis Antigen Arrays for the in-depth Characterization of the Serological Response of TB Infected Patient Cohorts
Rimmele S
Doktorarbeit, Mathematisch-Naturwissenschaftliche Fakultät, Universität Tübingen. 2012. 134 Seiten.
2012
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Receptor tyrosine kinase inhibitor profiling using bead-based multiplex sandwich immunoassays
Poetz O, Schneiderhan-Marra N, Henzler T, Herget T, Joos TO
Methods Mol Biol. 2012;795:191-202. doi: 10.1007/978-1-61779-337-0_13.
2012
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The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice
Ziegler M, Elvers M, Baumer Y, Leder C, Ochmann C, Schonberger T, Jurgens T, Geisler T, Schlosshauer B, Lunov O, Engelhardt S, Simmet T, Gawaz M
Circulation. 2012 Feb 7;125(5):685-96. Epub 2012 Jan 5
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Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V.
Schmees C, Villaseñor R, Zheng W, Ma H, Zerial M, Heldin CH, Hellberg C
Mol Biol Cell. 2012 Jul 1; 23(13): 2571–2582. doi: 10.1091/mbc.E11-04-0317
2012
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A Miniaturized Ligand Binding Assay for EGFR
Schwenk JM, Poetz O, Zeillinger R, Joos T
Int J Proteomics. 2012; 2012: 247059. doi: 10.1155/2012/247059
2012
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Neurofascin: A switch between neuronal plasticity and stability
Kriebel M, Wuchter J, Trinks S, Volkmer H
Int J Biochem Cell Biol. 2012 May; 44(5): 694-697. doi: 10.1016/j.biocel.2012.01.012
2012
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Entwicklung eines Immunoassays zur Quantifizierung von ALT 1 und ALT 2 in humanen Proben
Filomena A
Diplomarbeit, Interfakultäres Institut für Biochemie, Eberhard Karls Universität Tübingen. 2012. 133 Seiten.
2012
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Analyse der Bindungseigenschaften von beta-Catenin nach Phosphorylierung von Ser552 und Ser675
Goehring V
Diplomarbeit, Interfaktultäres Institut für Biochemie, Eberhard Karls Universität Tübingen. 2012. 80 Seiten.
2012
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Treatment with Actovegin(R) Improves Sensory Nerve Function and Pathology in Streptozotocin-Diabetic Rats via Mechanisms Involving Inhibition of PARP Activation
Dieckmann A, Kriebel M, Andriambeloson E, Ziegler D, Elmlinger M
Exp Clin Endocrinol Diabetes. 2012 Mar 120(3):132-8.
2012
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A biomarker panel to discriminate between systemic inflammatory response syndrome and sepsis and sepsis severity
Punyadeera C, Schneider EM, Schaffer D, Hsu HY, Joos TO, Kriebel F, Weiss M, Verhaegh WF
J Emerg Trauma Shock. 2010 Jan;3(1):26-35. doi: 10.4103/0974-2700.58666
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2011 |
Developmental dynamics of gap junction based neuronal coupling in the rat inferior olive
Mueller JR, Kriebel M, Volkmer H, Thier P
Neuroscience Meeting Planer. Washington DC: Society for Neuroscience, 2011.
2011
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2011 |
Enhanced predictive drug development: Functional screening of the GABAAR alpha1 subunit using receptor-specific RNA inference, MEA recordings and substance classification
Bader BM, Kniest S, Jügelt K, Kriebel M, Volkmer H, Schroeder OH-U, Gramowski-Voss A
euroscience Meeting Planer. Program No. 41.13/E24. 2011. Washington, DC: Society for Neuroscience, 2011.
2011
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2011 |
Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays
Pfeiffer T, Kraushaar U, Düfer M, Schönecker S, Haspel D, Günther E, Drews G, Krippeit-Drews P
Europ. J. Physiol. 2011, 462 (6): 835-840. DOI 10.1007/s00424-011-1029-z
2011
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2011 |
Bioartificial reconstruction of peripheral nerves using the rat median nerve model
Sinis N, Kraus A, Drakotos D, Doser M, Schlosshauer B, Muller HW, Skouras E, Bruck JC, Werdin F
Ann Anat. 2011 Jul;193(4):341-6. Epub 2011 Mar 22. DOI 10.1016/j.aanat.2011.02.018
2011
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2011 |
The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo.
Min TH, Kriebel M, Hou S, Pera EM
Dev Biol. 2011 Oct 1;358(1):262-76. DOI 10.1016/j.ydbio.2011.07.035
2011
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2011 |
Numerical modelling and measurement of cell trajectories in 3-D under the influence of dielectrophoretic and hydrodynamic forces
Holzner F, Hagmeyer B, Schütte J, Kubon M, Angres B, Stelzle M
Electrophoresis. 2011 August; 32(17): 2366-2376. DOI 10.1002/elps.201100026
2011
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2011 |
Extracellular voltage noise probes the interfaces between retina and silicon chip
Zeitler R, Fromherz P, Zeck G
Applied Physics Letters. 2011 Dec; 99: 263702. DOI 10.1063/1.3672224
2011
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2011 |
Medicinal Chemistry Approaches for the Inhibition of the p38 MAPK Pathway
Laufer L, Margutti S, Hauser D
2011 in Protein Kinases as Drug Targets. G. M. B. Klebl, M. Hamacher. Weinheim, Wiley-VCH Verlag GmbH & Co. KGaA.
2011
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2011 |
Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acid supply
Bernhard W, Raith M, Pynn CJ, Gille C, Stichtenoth G, Stoll D, Schleicher E, Poets CF
J Appl Physiol. 2011 Aug;111(2):449-57. Epub 2011 Jun 2. doi:10.1152/japplphysiol.00766.2010.
2011
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2011 |
Neuroprotective and anti-oxidative effects of the hemodialysate actovegin on primary rat neurons in vitro
Elmlinger MW, Kriebel M, Ziegler D
Neuromolecular Med. 2011 Dec;13(4):266-74. Epub 2011 Oct 9. doi: 10.1007/s12017-011-8157-7
2011
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2011 |
Neuronal and glial responses to siRNA-coated nerve guide implants in vitro
Hoffmann N, Mittnacht U, Hartmann H, Baumer Y, Kjems J, Oberhoffner S, Schlosshauer B
Neurosci Lett. 2011 Apr 20;494(1):14-8. Epub 2011 Feb 23. DOI 10.1016/j.neulet.2011.02.043
2011
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2011 |
Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response
Zeck G, Lambacher A, Fromherz P
PLoS One. 2011;6(6):e20810. Epub 2011 Jun 2.
2011
Zur Publikation
2011 |
A generic operational strategy to qualify translational safety biomarkers
Matheis K, Laurie D, Andriamandroso C, Arber N, Badimon L, Benain X, Bendjama K, Clavier I, Colman P, Firat H, Goepfert J, Hall S, Joos T, Kraus S, Kretschmer A, Merz M, Planatscher H, Schneiderhan-Marra N
Drug Discov Today. 2011 July; 16(13-14): 600-608. DOI 10.1016/j.drudis.2011.04.011
2011
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2011 |
The cell adhesion molecule neurofascin stabilizes axo-axonic GABAergic terminals at the axon initial segment
Kriebel M, Metzger J, Trinks S, Chugh D, Harvey RJ, Harvey K, Volkmer H
J Biol Chem. 2011 Jul 8; 286(27): 24385–24393. doi: 10.1074/jbc.M110.212191
2011
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2011 |
Sandwich Immunoassay for Soluble Glycoprotein VI in Patients with Symptomatic Coronary Artery Disease
Bigalke B, Poetz O, Kremmer E, Geisler T, Seizer P, Puntmann VO, Phinikaridou A, Chiribiri A, Nagel E, Botnar RM, Joos T, Gawaz M
Clin Chem. 2011 Jun;57(6):898-904. Epub 2011 Apr 7. DOI: 10.1373/clinchem.2010.158527
2011
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2011 |
Telomerase-based immortalization modifies the angiogenic/inflammatory responses of human coronary artery endothelial cells
Baumer Y, Scholz B, Ivanov S, Schlosshauer B
Exp Biol Med (Maywood). 2011 Jun 1;236(6):692-700. DOI: 10.1258/ebm.2011.010300
2011
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2011 |
Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review
Mandenius CF, Steel D, Noor F, Meyer T, Heinzle E, Asp J, Arain S, Kraushaar U, Bremer S, Class R, Sartipy P
J Appl Toxicol. April 2011; 31(3): 191-205. https://doi.org/10.1002/jat.1663
2011
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2011 |
The cell adhesion molecule neurofascin stabilizes axo-axonic GABAergic terminals at the axon initial segment
Kriebel M, Metzger J, Trinks S, Chugh D, Harvey RJ, Harvey K, Volkmer H
J Biol Chem. 2011 Jul 8; 286(27): 24385–24393. doi: 10.1074/jbc.M110.212191
2011
Zur Publikation
2011 |
TRPV Channel Expression in Human Skin and Possible Role in Thermally Induced Cell Death
Radtke C, Sinis N, Sauter M, Jahn S, Kraushaar U, Guenther E, Rodemann HP, Rennekampff HO
J Burn Care Res. 2011 Jan-Feb;32(1):150-9. DOI 10.1097/BCR.0b013e318203350c
2011
Zur Publikation
2011 |
Molecular indicators of non-sentinel node status in breast cancer determined in preoperative biopsies by multiplexed sandwich immunoassays
Sauer G, Schneiderhan-Marra N, Muche R, Koretz K, Kazmaier C, Kreienberg R, Joos T, Deissler H
J Cancer Res Clin Oncol. 2011 Aug;137(8):1175-84. Epub 2011 Apr 24.
2011
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2011 |
Network oscillations in rod-degenerated mouse retinas
Menzler J, Zeck G
J Neurosci. 2011 Feb 9;31(6):2280-91. DOI: 10.1523/JNEUROSCI.4238-10.2011
2011
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2011 |
Cell Type-Specific and Site Directed N-Glycosylation Pattern of FcgammaRIIIa
Zeck A, Pohlentz G, Schlothauer T, Peter-Katalinic J, Regula JT
J. Proteome Res. 2011;10(7):3031–3039. DOI: 10.1021/pr1012653
2011
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2011 |
Cell-based microarrays of infectious adenovirus encoding short hairpin RNA (shRNA)
Volkmer H, Weise F
Methods Mol Biol. 2011;706:97-106.
2011
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2011 |
Snapshots of protein dynamics and posttranslational modifications in one experiment - [beta]-catenin and its functions
Luckert K, Goetschel F, Sorger PK, Hecht A, Joos TO, Poetz O
Mol Cell Proteomics. 2011 May;10(5):M110.007377. Epub 2011 Mar 4. doi: 10.1074/mcp.M110.007377
2011
Zur Publikation
2010 |
Structure and mechanism of the magnesium-independent aromatic prenyltransferase CloQ from the clorobiocin biosynthetic pathway
Metzger U, Keller S, Stevenson CE, Heide L, Lawson DM
J Mol Biol. 2010 Dec 10;404(4):611-26. doi: 10.1016/j.jmb.2010.09.067. Epub 2010 Oct 12.
2010
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2010 |
Sequential multiplex analyte capturing for phospho-protein profiling
Poetz O, Henzler T, Hartmann M, Kazmaier C, Templin MF, Herget T, Joos TO
Mol Cell Proteomics. 2010 Nov;9(11):2474-81. Epub 2010 Aug 3. doi: 10.1074/mcp.M110.002709
2010
Zur Publikation
2010 |
Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver
Giera S, Braeuning A, Kohle C, Bursch W, Metzger U, Buchmann A, Schwarz M
Toxicol Sci. 2010 May;115(1):22-33. Epub 2010 Jan 30. doi: 10.1093/toxsci/kfq033.
2010
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2010 |
Minimum information about a protein affinity reagent (MIAPAR)
Bourbeillon J, Orchard S, Benhar I, Borrebaeck C, Templin M, de Daruvar A, Dubel S, Frank R, Gibson F, Gloriam D, Haslam N, Hiltker T, Humphrey-Smith I, Hust M, Juncker D, Koegl M, Konthur Z, Korn B, et al.
NatBiotechnol. 2010 Jul;28(7):650-3. doi: 10.1038/nbt0710-650.
2010
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2010 |
Triple-negative breast cancer: present challenges and new perspectives
Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sorlie T et al.
Mol Oncol. 2010 Jun;4(3):209-29. Epub 2010 Apr 24. doi: 10.1016/j.molonc.2010.04.006
2010
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2010 |
Targeting peptide termini - a novel immunoaffinity approach to reduce complexity in mass spectrometric protein identification
Hoeppe S, Schreiber TD, Planatscher H, Zell A, Templin MF, Stoll D, Joos TO, Poetz O
Mol Cell Proteomics. 2011 Feb;10(2):M110.002857. doi: 10.1074/mcp.M110.002857. Epub 2010 Oct 20.
2010
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2010 |
Sequential multiplex analyte capturing for phosphor-protein profiling
Poetz O, Henzler T, Hartmann M, Kazmaier C, Templin MF, Herget T, Joos TO
Mol Cell Proteomics. 2010 Nov; 9(11): 2474–2481. Published online 2010 Aug 3. doi: 10.1074/mcp.M110.002709
2010
Zur Publikation
2010 |
Optimal selection of epitopes for TXP-immunoaffinity mass spectrometry
Planatscher H, Supper J, Poetz O, Stoll D, Joos T, Templin MF, Zell A
Algorithms Mol Biol. 2010 Jun 25;5:28. doi: 10.1186/1748-7188-5-28
2010
Zur Publikation
2010 |
Multiplexed immunoassays for the analysis of breast cancer biopsies
Schneiderhan-Marra N, Sauer G, Kazmaier C, Hsu HY, Koretz K, Deissler H, Joos TO
Anal Bioanal Chem. 2010 Aug;397(8):3329-38. doi: 10.1007/s00216-010-3873-7. Epub 2010 Jul 18.
2010
Zur Publikation
2010 |
Biocompatible molecularly imprinted polymers for the voltage regulated uptake and release of l-glutamate in neutral pH solutions
von Hauff E, Fuchs K, Hellmann D Ch, Parisi J, Weiler R, Burkhardt C, Kraushaar U, Guenther E
Biosens Bioelectron. 2010 Oct 15;26(2):596-601. Epub 2010 Jul 16. doi: 10.1016/j.bios.2010.07.022
2010
Zur Publikation
2010 |
Does telomerase reverse transcriptase induce functional de-differentiation of human endothelial cells?
Baumer Y, Funk D, Schlosshauer B
Cell Mol Life Sci. 2010 Jul;67(14):2451-65. doi: 10.1007/s00018-010-0349-z. Epub 2010 Mar 30.
2010
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2010 |
Protein microarrays for personalized medicine
Yu X, Schneiderhan-Marra N, Joos TO
Clin Chem. 2010 Mar;56(3):376-87. Epub 2010 Jan 14. doi: 10.1373/clinchem.2009.137158
2010
Zur Publikation
2010 |
Suppression of adverse angiogenesis in an albumin-based hydrogel for articular cartilage and intervertebral disc regeneration
Scholz B, Kinzelmann C, Benz K, Mollenhauer J, Wurst H, Schlosshauer B
Eur Cell Mater. 2010 Jul 13;20:24-36; discussion 36-7.
2010
Zur Publikation
2010 |
Cardiac slices as a predictive tool for arrhythmogenic potential of drugs and chemicals
Meyer T, Stuerz K, Guenther E, Edamura M, Kraushaar U
Expert Opin Drug Metab Toxicol. 2010 Dec;6(12):1461-75. Epub 2010 Nov 11. doi: 10.1517/17425255.2010.526601.
2010
Zur Publikation
2010 |
Chemical stimulation of adherent cells by localized application of acetylcholine from a microfluidic system
Zibek S, Hagmeyer B, Stett A, Stelzle M
Front Neuroeng. 2010 Nov 26;3:113. doi: 10.3389/fneng.2010.00113. eCollection 2010.
2010
Zur Publikation
2010 |
Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets
Swanton C, Larkin JM, Gerlinger M, Eklund AC, Boehme KA, Volkmer H, Howell M, Stamp G, Downward J, Gore M, Futreal PA, Escudier B, Andre F, Albiges L, Beuselinck B, Oudard S, Hoffmann J, Gyorffy B et al.
Genome Med. 2010 Aug 11;2(8):53. doi: 10.1186/gm174.
2010
Zur Publikation
2010 |
In vivo and in vitro development of S- and M-cones in rat retina
Arango-Gonzalez B, Szabo A, Pinzon-Duarte G, Lukats A, Guenther E, Kohler K
Invest Ophthalmol Vis Sci. 2010 Oct;51(10):5320-7. Epub 2010 May 12. doi: 10.1167/iovs.09-4741.
2010
Zur Publikation
2010 |
Protein-protein-interactions in a multiplexed, miniaturized format a functional analysis of Rho GTPase activation and inhibition
Schmohl M, Rimmele S, Potz O, Kloog Y, Gierschik P, Joos TO, Schneiderhan-Marra N
Proteomics. 2010 Apr;10(8):1716-20. doi: 10.1002/pmic.200900597.
2010
Zur Publikation
2010 |
Subretinal electronic chips allow blind patients to read letters and combine them to words
Zrenner E, Bartz-Schmidt KU, Benav H, Besch D, Bruckmann A, Gabel VP, Gekeler F, Greppmaier U, Harscher A, Kibbel S, Koch J, Kusnyerik A, Peters T, Stingl K, Sachs H, Stett A, Szurman P, Wilhelm B, Wilke R
Proc. R. Soc. B. 2010 Nov; 278(1711). DOI 10.1098/rspb.2010.1747
2010
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2010 |
Tetrahydrochromenoimidazoles as Potassium-Competitive Acid Blockers (P-CABs): Structure-Activity Relationship of Their Antisecretory Properties and Their Affinity toward the hERG Channel (dagger)
Palmer AM, Chiesa V, Schmid A, Munch G, Grobbel B, Zimmermann PJ, Brehm C, Buhr W, Simon WA, Kromer W, Postius S, Volz J, Hess D
J Med Chem. 2010 May 13;53(9):3645-74. doi: 10.1021/jm100040c.
2010
Zur Publikation
2010 |
Bead-based protein-protein interaction assays for the analysis of Rho GTPase signaling
Rimmele S, Gierschik P, Joos TO, Schneiderhan-Marra N
J Mol Recognit. 2010 Nov-Dec;23(6):543-50. doi: 10.1002/jmr.1051.
2010
Zur Publikation
2009 |
The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria
Metzger U, Schall C, Zocher G, Unsold I, Stec E, Li SM, Heide L, Stehle T
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14309-14. doi: 10.1073/pnas.0904897106. Epub 2009 Aug 12.
2009
Zur Publikation
2009 |
Protein microarrays for diagnostic assays.
Hartmann M, Roeraade J, Stoll D, Templin MF, Joos TO
Anal Bioanal Chem. 2009 Mar;393(5):1407-16. Epub 2008 Sep 20. doi: 10.1007/s00216-008-2379-z.
2009
Zur Publikation
2009 |
Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS)
Bigalke B, Stellos K, Weig HJ, Geisler T, Seizer P, Kremmer E, Potz O, Joos T, May AE, Lindemann S, Gawaz M
Basic Res Cardiol. 2009 May;104(3):352-7. Epub 2009 Feb 3. doi: 10.1007/s00395-009-0779-7.
2009
Zur Publikation
2009 |
Neuroprotective effect of transretinal electrical stimulation on neurons in the inner nuclear layer of the degenerated retina
Schmid H, Herrmann T, Kohler K, Stett A
Brain Res Bull. 2009 Apr 6;79(1):15-25. Epub 2009 Jan 15. doi: 10.1016/j.brainresbull.2008.12.013.
2009
Zur Publikation
2009 |
Multiplex microsphere-based flow cytometric platforms for protein analysis and their application in clinical proteomics - from assays to results
Hsu HY, Joos TO, Koga H
Electrophoresis. 2009 Dec;30(23):4008-19. doi: 10.1002/elps.200900211.
2009
Zur Publikation
2009 |
Protein microarrays: potentials and limitations
Joos T, Bachmann J
Front Biosci. 2009 Jan 1;14:4376-85.
2009
Zur Publikation
2009 |
Expansion and Differentiation of Neural Progenitors Derived From the Human Adult Enteric Nervous System
Metzger M, Bareiss PM, Danker T, Wagner S, Hennenlotter J, Guenther E, Obermayr F, Stenzl A, Koenigsrainer A, Skutella T, Just L
Gastroenterology. 2009 Dec;137(6):2063-2073.e4. doi: 10.1053/j.gastro.2009.06.038. Epub 2009 Jun 21.
2009
Zur Publikation
2009 |
Analysis of Non-canonical Fibroblast Growth Factor Receptor 1 (FGFR1) Interaction Reveals Regulatory and Activating Domains of Neurofascin
Kirschbaum K, Kriebel M, Kranz EU, Poetz O, Volkmer H
J Biol Chem. 2009 Oct 16;284(42):28533-42. doi: 10.1074/jbc.M109.004440. Epub 2009 Aug 7.
2009
Zur Publikation
2009 |
Forster resonance energy transfer-based total internal reflection fluorescence reader for apoptosis
Bruns T, Angres B, Steuer H, Weber P, Wagner M, Schneckenburger H
J Biomed Opt. 2009 Mar-Apr;14(2):021003. doi: 10.1117/1.3055622.
2009
Zur Publikation
2009 |
An improved electrophysiological method to study peripheral nerve regeneration in rats
Werdin F, Grussinger H, Jaminet P, Kraus A, Manoli T, Danker T, Guenther E, Haerlec M, Schaller HE, Sinis N
J Neurosci Methods. 2009 Aug 30;182(1):71-7. Epub 2009 Jun 6. doi: 10.1016/j.jneumeth.2009.05.017
2009
Zur Publikation
2009 |
On display on a bug: a systematic approach to characterize antibodies
Knorpp T, Templin MF
Nat Methods. 2008 Dec;5(12):1003-4. DOI: 10.1038/nmeth1208-1003
2009
Zur Publikation
2009 |
Lokale Applikation von Deferroaxmin zur Verbesserung der Regeneration peripherer Nerven im Tierversuch
Werdin F, Scipio FD, Schonle P, Kraus A, Jaminet P, Koopmanns G, Danker T, Guenther E, Haerle M, Schaller HE, Geuna S, Mueller HW (2009)
Obere Extremitäten. 2009; 4(4): 217-223.
2009
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2009 |
Array-Technologien für die Multiparameteranalytik von Proteomen
Herget T, Henzler T, Hayes S, Joos T
2008. in: Schierack, Schröder. Mulitplex-DNA Mikropartikelpartien und deren Anwendung. Pabst Science Publishers. 3 - 15.
2009
Zur Publikation
2009 |
Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Pirnia F, Pawlak M, Thallinger GG, Gierke B, Templin MF, Kappeler A, Betticher DC, Gloor B, Borner MM
Proteomics. 2009 Jul;9(13):3535-48. doi: 10.1002/pmic.200800159.
2009
Zur Publikation
2009 |
Proteome wide screening using peptide affinity capture
Poetz O, Hoeppe S, Templin MF, Stoll D, Joos TO
Proteomics. 2009 Mar;9(6):1518-23. doi: 10.1002/pmic.200800842.
2009
Zur Publikation
2009 |
Local administration of DFO-loaded lipid particles improves recovery after end-to-end reconstruction of rat median nerve
Sinis N, Di Scipio F, Schonle P, Werdin F, Kraus A, Koopmanns G, Masanneck C, Hermanns S, Danker T, Guenther E, Haerle M, Schaller HE, Geuna S, Mueller HW
Restor Neurol Neurosci. 2009;27(6):651-62. doi: 10.3233/RNN-2009-0517.
2009
Zur Publikation
2009 |
Influence of platelet count on the expression of platelet collagen receptor glycoprotein VI (GPVI) in patients with acute coronary syndrome
Bigalke B, Stellos K, Stakos D, Joos T, Potz O, Geisler T, Bischofs C, Kremmer E, Kramer BF, Seizer P, May AE, Lindemann S, Gawaz M
Thromb Haemost. 2009 May;101(5):911-5.
2009
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2009 |
Regulation of p53--insights into a complex process
Boehme KA, Blattner C
Crit Rev Biochem Mol Biol. 2009 Nov-Dec;44(6):367-92.
2009
Zur Publikation
2008 |
Tumor promotion in liver of mice with a conditional Cx26 knockout.
Marx-Stoelting P, Mahr J, Knorpp T, Schreiber S, Templin MF, Ott T, Buchmann A, Schwarz M
Toxicol Sci. 2008 Jun;103(2):260-7. Epub 2008 Feb 27. doi: 10.1093/toxsci/kfn043
2008
Zur Publikation
2008 |
LED-based illumination system for the MEA60 system for full field stimulation of explanted retinas
Herrmann T, Krause T, Gerhardt M, Hesse M, Boven K-H, Stett A
Proceedings MEA Meeting 2008, Reutlingen, BioPro edition, Vol.5, p.199-200, ISBN 3-938345-05-5
2008
Zur Publikation
2008 |
Inhomogeneity of Cell Properties In The Cardiomyocyte Derived HL-1 Cell Line
Kraushaar U, Nagel J, Meyer T, Guenther E
Proceedings MEA Meeting 2008, Reutlingen, BioPro edition; 5:186-187, ISBN 3-938345-05-5
2008
Zur Publikation
2008 |
Vitreous Levels of Bevacizumab and Vascular Endothelial Growth Factor-A in Patients with Choroidal Neovascularization.
Zhu Q, Ziemssen F, Henke-Fahle S, Tatar O, Szurman P, Aisenbrey S, Schneiderhan-Marra N, Xu X, Bevacizumab T, Grisanti S
Ophthalmology. 2008 Oct;115(10):1750-5, 1755.e1. doi: 10.1016/j.ophtha.2008.04.023. Epub 2008 Aug 16.
2008
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2008 |
Miniaturized parallelized sandwich immunoassays
Hsu HY, Wittemann S, Joos TO
Methods Mol Biol. 2007;428:247-62.
2008
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2008 |
Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases
Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO
Med Eng Phys. 2008 Oct;30(8):976-83. Epub 2008 Mar 3. doi: 10.1016/j.medengphy.2008.01.003
2008
Zur Publikation
2008 |
A membrane-bound FRET-based caspase sensor for detection of apoptosis using fluorescence lifetime and total internal reflection microscopy.
Angres B, Steuer H, Weber P, Wagner M, Schneckenburger H
Cytometry A. 2009 May;75(5):420-7. doi: 10.1002/cyto.a.20698
2008
Zur Publikation
2008 |
Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans
Woehrle T, Du W, Goetz A, Hsu HY, Joos TO, Weiss M, Bauer U, Brueckner UB, Marion Schneider E
Cytokine. 2008 Mar;41(3):322-9. Epub 2008 Jan 30. doi: 10.1016/j.cyto.2007.12.006
2008
Zur Publikation
2008 |
New frontiers in microarray technology development
Joos T, Kroeger P
Curr Opin Biotechnol. 2008 Feb;19(1):1-3. doi: 10.1016/j.copbio.2007.12.001. Epub 2008 Jan 18.
2008
Zur Publikation
2008 |
Expanding assay dynamics: a combined competitive and direct assay system for the quantification of proteins in multiplexed immunoassays
Hartmann M, Schrenk M, Dottinger A, Nagel S, Roeraade J, Joos TO, Templin MF
Clin Chem. 2008 Jun;54(6):956-63. Epub 2008 Apr 24. doi: 10.1373/clinchem.2007.099812
2008
Zur Publikation
2008 |
Prediction of Nodal Involvement in Breast Cancer Based on Multiparametric Protein Analyses from Preoperative Core Needle Biopsies of the Primary Lesion.
Sauer G, Schneiderhan-Marra N, Kazmaier C, Hutzel K, Koretz K, Muche R, Kreienberg R, Joos T, Deissler H
Clin Cancer Res. 2008 Jun 1;14(11):3345-3353. doi: 10.1158/1078-0432.CCR-07-4802.
2008
Zur Publikation
2008 |
A Cryptic Vascular Endothelial Growth Factor T-Cell Epitope: Identification and Characterization by Mass Spectrometry and T-Cell Assays
Weinzierl AO, Maurer D, Altenberend F, Schneiderhan-Marra N, Klingel K, Schoor O, Wernet D, Joos T, Rammensee HG, Stevanovic S (2008)
Cancer Res. 2008 Apr 1;68(7):2447-54. doi: 10.1158/0008-5472.CAN-07-2540
2008
Zur Publikation
2008 |
A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries
Oehmig A, Klotzbucher A, Thomas M, Weise F, Hagner U, Brundiers R, Waldherr D, Lingnau A, Knappik A, Kubbutat, MH, Joos TO, Volkmer H
BMC Genomics. 2008 Sep 24;9:441. doi: 10.1186/1471-2164-9-441.
2008
Zur Publikation
2008 |
p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK
Boehme KA, Kulikov R, Blattner C
Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7785-90. Epub 2008 May 27. doi: 10.1073/pnas.0703423105. Epub 2008 May 27.
2008
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2007 |
Xeya3 regulates survival and proliferation of neural progenitor cells within the anterior neural plate of Xenopus embryos
Kriebel M, Müller F, Hollemann T
Dev Dyn. 2007 Jun;236(6):1526-34. DOI: 10.1002/dvdy.21170
2007
Zur Publikation
2007 |
Retinal charge sensitivity and spatial discrimination obtainable by subretinal implants: key lessons learned from isolated chicken retina.
Stett A, Mai A, Herrmann T
J Neural Eng. 2007 Mar;4(1):S7-16. Epub 2007 Feb 20. DOI: 10.1088/1741-2560/4/1/S02
2007
Zur Publikation
2007 |
Identification of NCAM-binding peptides promoting neurite outgrowth via a heterotrimeric G-protein-coupled pathway
Hansen RK, Christensen C, Korshunova I, Kriebel M, Burkarth N, Kiselyov VV, Olsen M, Ostergaard S, Holm A, Volkmer H, Walmod PS, Berezin V, Bock E
J Neurochem. 2007 Nov;103(4):1396-407. Epub 2007 Sep 13. DOI: 10.1111/j.1471-4159.2007.04894.x
2007
Zur Publikation
2007 |
Neurofascin regulates the formation of gephyrin clusters and their subsequent translocation to the axon hillock of hippocampal neurons
Burkarth N, Kriebel M, Kranz EU, Volkmer H
Mol Cell Neurosci. 2007 Sep;36(1):59-70. Epub 2007 Jun 27. DOI: 10.1016/j.mcn.2007.06.001
2007
Zur Publikation
2007 |
Long nerve gaps limit the regenerative potential of bioartificial nerve conduits filled with Schwann cells
Sinis N, Schaller H-E, Schulte-Eversum C, Becker ST, Schlosshauer B, Doser M, Rösner H, Dietz K, Müller H-W, Haerle M
Restor Neurol Neurosci. 2007;25(2):131-41.
2007
Zur Publikation
2007 |
Expression of serine/threonine protein-kinases and related factors in normal monkey and human retinas: the mechanistic understanding of a CDK2 inhibitor induced retinal toxicity
Saturno G, Pesenti M, Cavazzoli C, Rossi A, Giusti A, Gierke B, Pawlak M, Venturi M
Toxicol Pathol. 2007 Dec;35(7):972-83. DOI: 10.1080/01926230701748271
2007
Zur Publikation
2007 |
Aging Schwann cells in vitro
Funk D, Fricke C, Schlosshauer B
Eur J Cell Biol. 2007 Apr;86(4):207-19. Epub 2007 Feb 20. DOI: 10.1016/j.ejcb.2006.12.006
2007
Zur Publikation
2007 |
New cell models and assays in cardiac safety profiling
Meyer T, Sartipy P, Blind F, Leisgen C, Guenther E
Expert Opin Drug Metab Toxicol. 2007 Aug;3(4):507-17. DOI: 10.1517/17425225.3.4.507
2007
Zur Publikation
2007 |
Blood-retina barriers
Schlosshauer B
Handbook of Neurochemistry and Molecular Neurobiology 3rd Edition, Vol. 11 Neural Membranes and Transport (Ed. A. Lajtha and M.E.A Reith), Springer Publishers, New York, Springer Publishers N.Y., pages 486-506.
2007
Zur Publikation
2006 |
Protein chip based miniaturized assay for the simultaneous quantitative monitoring of cancer biomarkers in tissue extracts
Weissenstein U, Schneider MJ, Pawlak M, Cicenas J, Eppenberger-Castori S, Oroszlan P, Ehret S, Geurts-Moespot A, Sweep FC, Eppenberger U
Proteomics. 2006; 6 (5): 1427-1436. DOI: 10.1002/pmic.200500078
2006
Zur Publikation
2006 |
The Retinasensor: An In vitro Tool to Study Drug Effects on Retinal Signaling.
Guenther E, Herrmann T, Stett A
Advances in Network Electrophysiology Using Multi Electrode Arrays. 2006. Springer, Berlin: 321-331.
2006
Zur Publikation
2006 |
Increasing robustness and sensitivity of protein microarrays through microagitation and automation.
Hartmann M, Toegl A, Kirchner R, Templin MF, Joos TO
Anal Chim Acta. 2006 Mar 30;564(1):66-73. Epub 2006 Feb 21. DOI: 10.1016/j.aca.2006.01.041
2006
Zur Publikation
2006 |
Current perspectives in protein array technology
Kricka LJ, Master SR, Joos TO, Fortina P
Ann Clin Biochem. 2006 Nov ; 43 (PT 6): 457-67.
2006
Zur Publikation
2006 |
Caspase-3 activation, Bcl-2 contents, and soluble FAS-ligand are not related to the inflammatory marker profile in patients with sepsis and septic shock
Kriebel F, Wittemann S, Hsu HY, Joos T, Weiss M, Schneider EM
Ann N Y Acad Sci. 2006 Dec ; 1090: 168-76. DOI: 10.1196/annals.1378.018
2006
Zur Publikation
2006 |
Combination of engineered neural cell adhesion molecules and GDF-5 for improved neurite extension in nerve guide concepts
Niere M, Braun B, Gass R, Sturany S, Volkmer H
Biomaterials. 2006 Jun;27(18):3432-40. Epub 2006 Feb 23. DOI: 10.1016/j.biomaterials.2006.01.037
2006
Zur Publikation
2006 |
Physical and biological performance of a novel block copolymer nerve guide.
Lietz M, Ullrich A, Schulte-Eversum C, Oberhoffner S, Fricke C, Muller HW, Schlosshauer B
Biotechnol Bioeng. 2006 Jan 5;93(1):99-109. DOI: 10.1002/bit.20688
2006
Zur Publikation
2006 |
The long and difficult road to the diagnostic market: protein microarrays.
Joos TO, Berger H
Drug Discov Today. 2006 Nov;11(21-22):959-61. Epub 2006 Oct 2. DOI: 10.1016/j.drudis.2006.09.014
2006
Zur Publikation
2006 |
Protein Microarrays - Neue Systeme für die Proteomforschung
Joos TO, Pawlak M, Templin M, Stoll D
GIT Labor-Fachzeitschrift. 2006; 10, page 890-892.
2006
Zur Publikation
2006 |
A regulated switch of chick neurofascin isoforms modulates ligand recognition and neurite extension.
Pruss T, Kranz E U, Niere M, Volkmer H
Mol Cell Neurosci. 2006 Feb;31(2):354-65. Epub 2005 Nov 28. DOI: 10.1016/j.mcn.2005.10.009
2006
Zur Publikation
2006 |
Assessent of drug effects on myocyte function in vitro
Guenther E, Henes K, Pankow S, Boven KH, Meyer T
International Meeting on Substrate-Integrated Micro Electrode Arrays. BioPro. Reutlingen. 2006; 3: 136-139.
2006
Zur Publikation
2006 |
Guidelines for terminology for microtechnology in clinical laboratories.
Wilding P, Joos T, Kricka LJ, Shi L
Pure Appl. Chem. 2006; 78(3): 677-684. doi:10.1351/pac200678030677
2006
Zur Publikation
2005 |
Protein microarrays: applications and future challenges
Stoll D, Templin MF, Bachmann J, Joos TO
Curr Opin Drug Discov Devel. 2005 Mar;8(2):239-52.
2005
Zur Publikation
2005 |
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
Kulikov R, Boehme KA, Blattner C
Mol Cell Biol. 2005 Aug;25(16):7170-80. DOI: 10.1128/MCB.25.16.7170-7180.2005
2005
Zur Publikation
2005 |
Protein Microarrays - A Promising Tool for Cancer Diagnosis
Schneiderhan-Marra N, Kirn A, Döttinger A, Templin M, Sauer G, Deissler H, Joos TO
Cancer Genomics & Proteomics. 2005 Jan; 2(1): 37-42.
2005
Zur Publikation
2005 |
Protein biochips: the calm before the storm.
Bodovitz S, Joos T, Bachmann J
Drug Discov Today. 2005 Feb 15; 10(4): 283-287. DOI: 10.1016/S1359-6446(05)03373-8
2005
Zur Publikation
2005 |
Age-dependent changes in the regulation mechanisms for intracellular calcium ions in ganglion cells of the mouse retina.
Mann M, Haq W, Zabel T, Guenther E, Zrenner E, Ladewig T
Eur J Neurosci. 2005 Dec;22(11):2735-43. DOI: 10.1111/j.1460-9568.2005.04475.x
2005
Zur Publikation
2005 |
Identification of P2Y receptor subtypes in human Müller glial cells by physiology, single cell RT-PCR, and immunohistochemistry.
Fries JE, Goczalik IM, Wheeler-Schilling TH, Kohler K, Guenther E, Wolf S, Wiedemann P, Bringmann A, Reichenbach A, Francke M, Pannicke T
Invest Ophthalmol Vis Sci. 2005 Aug;46(8):3000-7. DOI: 10.1167/iovs.05-0043
2005
Zur Publikation
2005 |
Protein microarrays: catching the proteome.
Poetz O, Schwenk JM, Kramer S, Stoll D, Templin MF, Joos TO
Mech Ageing Dev. 2005 Jan;126(1):161-70. DOI: 10.1016/j.mad.2004.09.030
2005
Zur Publikation
2005 |
Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1)
Budde A, Schneiderhan-Marra N, Petersen G, Brune B
Oncogene. 2005; 24(10): 1802-8. DOI: 10.1038/sj.onc.1208369
2005
Zur Publikation
2005 |
Differences in herbal and dietary supplement use in the Hispanic and non-Hispanic pediatric populations.
Guenther E, Mendoza J, Crouch BI, Moyer-Mileur LJ, Junkins EP Jr.
Pediatr Emerg Care. 2005 Aug;21(8):507-14.
2005
Zur Publikation
2005 |
Protein microarrays for antibody profiling: Specificity and affinity determination on a chip.
Poetz O, Ostendorp R, Brocks B, Schwenk JM, Stoll D, Joos TO, Templin MF
Proteomics. 2005 Jun;5(9):2402-11. DOI: 10.1002/pmic.200401299
2005
Zur Publikation
2004 |
Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein in Trypanosoma brucei.
Engstler M, Thilo L, Weise F, Grunfelder CG, Schwarz H, Boshart M, Overath P
J Cell Sci. 2004 Mar 1;117(Pt 7):1105-15. DOI: 10.1242/jcs.00938
2004
Zur Publikation
2004 |
Functional re-establishment of the perforant pathway in organotypic co-cultures on microelectrode arrays
Hofmann F, Guenther E, Hammerle H, Leibrock C, Berezin V, Bock E, Volkmer H
Brain Res. 2004 Aug 13;1017(1-2):184-96. DOI: 10.1016/j.brainres.2004.05.044
2004
Zur Publikation
2004 |
Expression of P2Y1, P2Y2, P2Y4, and P2Y6 receptor subtypes in the rat retina.
Fries JE, Wheeler-Schilling TH, Guenther E, Kohler K
Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3410-7. DOI: 10.1167/iovs.04-0141
2004
Zur Publikation
2004 |
ATP-induced non-neuronal cell permeabilization in the rat inner retina
Innocenti B, Pfeiffer S, Zrenner E, Kohler K, Guenther E
J Neurosci. 2004 Sep 29;24(39):8577-83. DOI: 10.1523/JNEUROSCI.2812-04.2004
2004
Zur Publikation
2004 |
The proteomics bottleneck: strategies for preliminary validation of potential biomarkers and drug targets
Bodovitz S, Joos T
Trends Biotechnol. 2004 Jan;22(1):4-7. DOI: 10.1016/j.tibtech.2003.10.013
2004
Zur Publikation
2004 |
Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline
Bernhard W, Pynn CJ, Jaworski A, Rau GA, Hohlfeld JM, Freihorst J, Poets CF, Stoll D, Postle AD
Am J Respir Crit Care Med. 2004 Jul 1;170(1):54-8. Epub 2004 Mar 24. DOI:10.1164/rccm.200401-089OC
2004
Zur Publikation
2004 |
Automated higher-throughput compound screening on ion channel targets based on the Xenopus laevis oocyte expression system
Pehl U, Leisgen C, Gampe K, Guenther E
Assay Drug Dev Technol. 2004; 2(5): 515-24. DOI: 10.1089/adt.2004.2.515
2004
Zur Publikation
2004 |
QT-screen: high-throughput cardiac safety pharmacology by extracellular electrophysiology on primary cardiac myocytes
Meyer T, Leisgen C, Gonser B, Günther E
Assay Drug Dev Technol. 2004 Oct;2(5):507-14. DOI: 10.1089/adt.2004.2.507
2004
Zur Publikation
2004 |
Distribution of metabotropic P2Y receptors in the rat retina: a single-cell RT-PCR study.
Fries JE, Wheeler-Schilling TH, Kohler K, Guenther E
Brain Res Mol Brain Res. 2004 Nov 4;130(1-2):1-6. DOI: 10.1016/j.molbrainres.2004.06.041
2004
Zur Publikation
2004 |
Protein microarrays and multiplexed sandwich immunoassays: what beats the beads?
Templin MF, Stoll D, Bachmann J, Joos TO
Comb Chem High Throughput Screen. 2004 May;7(3):223-9.
2004
Zur Publikation
2004 |
Microarray technology: an increasing variety of screening tools for proteomic research.
Stoll D, Bachmann J, Templin MF, Joos TO
DDT:Targets. 2004 Dec 15; 9(24): 10-7
2004
Zur Publikation
2004 |
Micro-electrode arrays in cardiac safety pharmacology: a novel tool to study QT interval prolongation
Meyer T, Guenther E, Boven KH
Drug Safety.2004 27(11):763-772. DOI: 10.2165/00002018-200427110-00002
2004
Zur Publikation
2004 |
Homophilic interactions of chick neurofascin in trans are important for neurite induction
Pruss T, Niere M, Kranz EU, Volkmer H
Eur J Neurosci. 2004 Dec;20(11):3184-8. DOI: 10.1111/j.1460-9568.2004.03773.x
2004
Zur Publikation
2004 |
Effects of brain-derived neurotrophic factor on cell survival, differentiation and patterning of neuronal connections and Muller glia cells in the developing retina
Pinzon-Duarte G, Arango-Gonzalez B, Guenther E, Kohler K
Eur J Neurosci. 2004 Mar;19(6):1475-84. DOI: 10.1111/j.1460-9568.2004.03252.x
2004
Zur Publikation
2004 |
Developmental plasticity of NMDA receptor function in the retina and the influence of light.
Guenther E, Schmid S, Wheeler-Schilling T, Albach G, Grunder T, Fauser S, Kohler K
FASEB J. 2004 Sep;18(12):1433-5. Epub 2004 Jul 9. DOI: 10.1096/fj.03-0618fje
2004
Zur Publikation
2004 |
Retinal colocalization and in vitro interaction of the glutamate transporter EAAT3 and the serum- and glucocorticoid-inducible kinase SGK1
Schniepp R, Kohler K, Ladewig T, Guenther E, Henke G, Palmada M, Boehmer C, Rothstein JD, Broer S, Lang F
Invest Ophthalmol Vis Sci. 2004 May;45(5):1442-9.
2004
Zur Publikation
2004 |
BDNF regulates NMDA receptor activity in developing retinal ganglion cells
Ladewig T, Fellner S, Zrenner E, Kohler K, Guenther E
Neuroreport. 2004 Nov 15;15(16):2495-9.
2004
Zur Publikation
2003 |
Propofol for procedural sedation in children in the emergency department
Bassett KE, Anderson JL, Pribble CG, Guenther E
Ann Emerg Med. 2003 Dec;42(6):773-82. DOI: 10.1016/S019606440300619X
2003
Zur Publikation
2003 |
Propofol sedation by emergency physicians for elective pediatric outpatient procedures
Guenther E, Pribble CG, Junkins ER Jr, Kadish HA, Bassett KE, Nelson DS
Ann Emerg Med. 2003 Dec;42(6):783-91. DOI: 10.1016/S0196064403006346
2003
Zur Publikation
2003 |
Endocytosis of a glycosylphosphatidylinositol-anchored protein via clathrin-coated vesicles, sorting by default in endosomes, and exocytosis via RAB11-positive carriers.
Grunfelder CG, Engstler M, Weise F, Schwarz H, Stierhof YD, Morgan GW, Field MC, Overath P
Mol Biol Cell. 2003 May;14(5):2029-40. Epub 2003 Feb 6. doi: 10.1091/mbc.E02-10-0640
2003
Zur Publikation
2003 |
Protein microarrays: promising tools for proteomic research
Templin MF, Stoll D, Schwenk JM, Pötz O, Kramer S, Joos TO
Proteomics. 2003 Nov;3(11):2155-66.
2003
Zur Publikation
1998 |
Enhanced antigenicity of a four-contact-residue epitope of the measles virus hemagglutinin protein by phage display libraries: evidence of a helical structure in the putative active site
Deroo S, El Kasmi K, Fournier P, Theisen D, Brons N, Herrmann M, Desmet J, Muller C
Molecular Immunology. 1998 June; 35(8):435-443. doi: 10.1016/S0161-5890(98)00057-1
1998
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1998 |
Combinatorial Peptide and Nonpeptide Libraries
Wiesmüller KH, Feiertag S, Fleckenstein B, Kienle S, Stoll D, Herrmann M, Jung G
VCH Publishers, Weinheim, Germany 1996
1998
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1970 |
Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures
Schumacher D, Andrieux G, Boehnke K, Keil M, Silvestri A, Silvestrov M, Keilholz U, Haybaeck J, Erdmann G, Sachse C, Templin M, Hoffmann J, Boerries M, Schafer R, Regenbrecht CRA
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