Neurotox Assays

Dr. Udo Kraushaar
Group Leader Electrophysiology

Neurotox & Electrophysiology: We use Patch Clamp, MEA and Ca Imaging to improve research and enable discoveries.

Use our robust electrophysiological techniques for your pharmaceutical research: patch clamp, MEA and calcium imaging. As a trusted partner in the industry, we offer assays to help improve your drug discovery process. Our integrated approach combines advanced technologies to ensure accuracy and sensitivity in the study of neuronal activity and toxicity.
Our comprehensive neurotoxicity analysis services are tailored to meet the unique needs of our pharmaceutical industry clients. Partner with us and experience the benefits of working with a dedicated team of experts in the field. Together, we can drive innovation and success in the pharmaceutical industry.

 

Our services

  • drug profiling support
  • Use of various cellular systems, e.g.
  • Primary neurons of different brain areas (mouse, rat)
  • hiPSC derived neurons
  • acute and organotypically cultured brain slices
  • Whole-mount retina

 

Methods

  • Manual patch clamp
  • Neural Network Analysis (MEA)
  • microERG (MEA)
  • Ca2+ imaging (temporal-spatial high resolution or HTS (96/384 well format)

 

Instruments

  • Various manual patch clamp setups
  • Various MEA systems (MEA2100, Multiwell)
  • Hamamatsu FDSS/µCell HTS Imaging