Bio­materials engine­ering

Using electrospinning, the Biomaterials Engineering group develops fibrous, 3D carriers from synthetic polymers or proteins and extracellular matrix components. These are used in regenerative medicine as implants, test systems and drug release systems. In addition, the cell-material interaction is analyzed. Depending on the requirements, the material composition as well as the fiber and pore sizes and the mechanical properties are varied in order to influence the biocompatibility as well as the cell behavior.

Techniques, methods and equipment

  • Electrospinning
  • Surface modification of materials
  • Cell-material interaction studies (human primary cells, stem cells, immune cells, cell lines)
  • Processing of ECM molecules
  • Production of drug release systems
  • biocompatibility assays
  • 3D in vitro test systems

Services

  • Production of fibrous materials of variable fiber sizes and shapes by electrospinning
  • Encapsulation of active substances
  • Development of implants and in vitro test systems
  • Cell-material interaction studies (cell lines and primary cells)
  • Modification of surfaces
  • Production of layer structures (hydrogel - electro-spun scaffold)