Speed up to find the right ones: rapid discovery of functional nanobodies
Nat Struct Mol Biol. 2018 Mar;25(3):199-201.
Nanobodies have emerged as highly versatile and useful binding molecules in biomedical research. A technical report describes a cost- and time-effective in vitro platform that facilitates the generation of desired nanobodies, including conformationally selective nanobodies against agonist-bound G-protein-coupled receptors (GPCRs).