Label-free detection of tumor markers in a colon carcinoma tumor progression model by confocal Raman microspectroscopy
Scalfi-Happ C, Rück A, Udart M, Hauser C, Dürr C, Kriebel M
Proc. SPIE. Clinical and Biomedical Spectroscopy and Imaging III. 2013 June 18; 87980B. doi:10.1117/12.2032459;
Living colon carcinoma cells were investigated by confocal Raman microspectroscopy. An in vitro model of tumor progression was established. Evaluation of data sets by cluster analysis reveals that lipid bodies might be a valuable diagnostic parameter for early carcinogenesis.