Challenging the pipeline
Loskill P, Hardwick R N, Roth A
Stem Cell Reports
Volume 16, Issue 9, 14 September 2021, Pages 2033-2037
This commentary presents a thought experiment seeking to answer the key question: “If you were to put aside all the traditional drug discovery processes and start a new drug discovery program that places the highest priority on human and disease-relevant models throughout the entire process, how could it be done?”