Analysis of Hydrogels
Biointerfacial Technologies
Senior Principal Scientist
The analysis of hydrogels in accordance with the ISO 10993 series of standards is used for risk assessment and to demonstrate biocompatibility for medical applications. The focus is on chemical characterization, the detection of toxic substances, and biological compatibility.
At the NMI, we characterize your hydrogels for regenerative medicine (based on ASTM F2900) and 3D bioprinting (based on VDI 5708). To this end, we offer the following qualitative and quantitative tests.
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Chemical Identity, based on ISO 10993-18
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Concentration Determination
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Molecular Weight Distribution
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Flow Properties
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Printability according to VDI 5708
Mass Transport
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Diffusion of Nutrients and Waste Products
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Release Rate of Biologically Active Substances
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Cell Migration
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Mechanical Properties
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Cell Encapsulation
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Environmental Stability, Material Characterization
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Diffusion of Nutrients and Waste Products
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Release Rate of Biologically Active Substances
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Cell Migration
Kinetics
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Gelling Time
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Swelling Behavior
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Matrix Degradation, based on ISO 10993-13
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In vitro cytotoxicity, based on ISO 10993-5
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Pyrogenicity, according to Ph. Eur. 2.6.14
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Antibacterial efficacy, based on ISO 22196 and ISO 20743
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Immune response to biomaterials
Additional
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3D cell distribution
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3D cell morphology
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Cell type-specific staining
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Cell viability (microscopic / quantitative)
NMI Natural and Medical Sciences Institute
at the University of Tübingen
Markwiesenstraße 55, 72770 Reutlingen
Tel.: +49 7121 51530-0
Mail:
info@nmi.de
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