Testing Services

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Dr. Dagmar Martin

T +49 (0)7121 51530-863

Research interests

cleaning validation
corrosion investigations
process analytics

Curriculum vitae

Since January 2019 Group Leader "Interface Characterization in the Production Process" at the NMI Reutlingen

2012 - 2018 Project Manager Medical Technology at the NMI Reutlingen

2007 - 2012 Product Manager at ancosys GmbH

2004 - 2007 Technical Editor at ancosys GmbH

2002 - 2004 Technical editor with focus on multimedia at Tanner Documents in Reutlingen, Germany

1999 - 2002 Programming of multimedia lecture contents as scientific employee at the University of Tübingen

1995 - 1999 Parental leave

1992 - 1995 PhD in Physical Chemistry at the University of Tübingen

1984 - 1991 Study of Chemistry at the University of Tübingen

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Liste

Dr. Hanna Hartmann

T +49 (0)7121 51530-872

E hanna.hartmann@nmi.de

Areas of activity

Characterization of surface properties (physicochemical, biological), Coating / modification of surfaces: Regulation of the adhesion of proteins, bacteria, cells, Analysis and functionalization of biodegradable materials, Immobilization and controlled release of active substances, Biomaterial processing: bioprinting, electrospinning, Services and R&D for Medical device companies

Stages of career

2017 - Present Head of Department Biomedicine and Materials Sciences, NMI, Reutlingen

2016 - Present Group leader Regenerative Biomaterials, NMI, Reutlingen

2015 - 2016 Deputy Group Leader Biomaterials, NMI, Reutlingen

2013 - 2015 Project leader, Group Biomaterials NMI, Reutlingen

2008 - 2013      Scientist, Group Regenerative Medicine I, NMI, Reutlingen

2007 - 2008      Post-Doc, Institute for Medical Microbiology and Hygiene, University of Tübingen,

2003 - 2006      PhD, Institute for Medical Microbiology and Hygiene, University of Tübingen, on host cell response after bacterial infection: apoptosis inhibition, HIF-1 activation

2002 - 2003      Diploma thesis, Chair of Biotechnology, University of Würzburg, on biocompatibility and functionality of biomaterials for immunoisolated transplantation of mammalian cells

1998 - 2002      Biology studies, University of Würzburg, Germany

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In the field of materials science, we offer a wide range of testing services in accredited and certified areas for medical implants.

Certificate Medical Devices (pdf download)
Certificate Materials (pdf download)

Material characterization

Topography: characterization of structures and defects: SEM, confocal white light microscopy, AFM
Coating analysis: Thickness, cross-section, layer sequence: FIB, SEM, TEM, ellipsometry
Compound distribution studies on surfaces: Raman
Chemical characterization (ISO 10993-18): Influence of production, storage and degradation, etc. XPS, FTIR, Raman, SNMS
Surface wettability: contact angle measurement
Thermal sample characteristics: DMA, DSC

Mechanical testing

Static material and component testing (tension, compression, bending, shear strain, peeling)

Corrosion tests

Corrosion resistance (ISO 10993-15, ASTM F 2129)
Degradation products from metals and alloys (DIN EN ISO 10993-15)
Surface analysis (light- and scanning electron microscopy)

Degradation analysis

Detection of degradation products: qualitative and quantitative (ISO 10993-13, -15, ISO 13781; e.g. polarography)
Degradation kinetics (samples and fragments)

Cleanliness testing

Comparison with reference surfaces
Filmic and particulate contaminations

Biological tests

In vitro cytotoxicity (ISO 10993-5, after extraction or in direct contact)
Cell-material interactions (adhesion, proliferation, morphology, functional markers)
In vitro tests for inflammation and immune response
Hemocompatibility (ISO 10993-4)
Antibacterial activity (DIN EN ISO 22196 and 20743)
Pyrogenicity (Ph. Eur.)