The project combines technological advances in the fields of molecular medicine, nanotechnology and digital technology to prepare industry in Baden-Württemberg for next-generation diagnostics. Demonstrators for future applications in telemedicine or by nursing staff will include a therapy-accompanying self-test for kidney transplant patients and a patient self-test for the detection of antibiotic-resistant pathogens and inflammation. The work packages at NMI focus on the fabrication, integration and optimization solid-state nanopores as low-noise single molecule sensors.