Areas of activity
polymer / polyelectrolyte thin films, nano technology, biomaterials, solid / liquid surfaces, foams
Stages of career
2011 - 2018 Head of Bioorganic Chemistry and Bioanalytics Division
2008 - 2018 Head of Biomaterials working group at the NMI
2005 - 2008 Research Associate at the Max Planck Institute for Colloids and Interfaces (MPI KG), Group Leader - Soft Thin Films
2002 - 2005 Scientific research (neutron reflectometry) Hahn-Meitner Institut, Berlin
1996 - 2002 PostDoc / Scientific employee at MPI KG, Dept. Interfaces, Golm/Potsdam
1996 Doctorate at the University of Sofia
1993-1998 Research stay at Bristol University, GB
1986 - 1995 Junior Professor of Physical Chemistry and Surface Chemistry (University of Sofia, Bulgaria)
1985 Diploma, Chemistry - Inorganic and Physical Chemistry
Publications
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Altered Proinflammatory Responses to Polyelectrolyte Multilayer Coatings Are Associated with Differences in Protein Adsorption and WettabilityBilling F, Walter B, Fink S, Arefaine E, Pickarski L, Maier S, Kretz R, Jakobi M, Feuerer N, Schneiderhan-Marra N, Burkhardt C, Templin M, Zeck A, Krastev R, Hartmann H, Shipp C.ACS Appl Mater Interfaces. 2021 Nov 24;13(46):55534-55549. doi: 10.1021/acsami.1c16175. Epub 2021 Nov 11. PMID: 34762399.
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Polyelectrolyte Coatings for Surface Modification of Medical ImplantsKrastev R, Rudt A, Xiong X, Hartmann HCurrent Directions in Biomedical Engineering. 2018; 4(1): 217-220. DOI: 10.1515/cdbme-2018-0053
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Biofunctionalization of surfaces using polyelectrolyte multilayersHartmann H, Krastev RBioNanoMaterials. 2017; 18(1-2). https://doi.org/10.1515/bnm-2016-0015
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Controlled heparinase-catalyzed degradation of polyelectrolyte multilayer capsules with heparin as responsive layerSun L, Xiong X, Qiaogen Z, Pingkai O, Krastev RJournal of Applied Polymer Science (ASAP). 2017 June 15, 134(23): 44916.
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Regulation of the growth, morphology, mechanical properties and biocompatibility of natural polysaccharide-based multilayers by Hofmeister anionsAndreeva TD, Hartmann H, Taneva StG, Krastev RJournal of Materials Chemistry, 2016, B 4(44): 7092-7100.
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Design of intelligent chitosan/heparin hollow microcapsules for drug deliverySun L, Xiong X, Zou Q, Ouyang P, Burkhardt C, Krastev RJournal of Applied Polymer Science. 2017 Feb 5;134(5), 44425.
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Fine-tuned PEGylation of chitosan to maintain optimal siRNA-nanoplex bioactivityGutoaia A, Schuster L, Margutti S, Laufer S, Schlosshauer B, Krastev R, Stoll D, Hartmann HCarbohydr Polym. 2016 Jun 5;143:25-34. doi: 10.1016/j.carbpol.2016.01.010. Epub 2016 Jan 8.
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The Hofmeister anion effect on morphology of polyelectrolyte multilayers for biofunctionalization of cardiovascular stentsAndreeva TD, Danailova AK, Terziyska P, Krumrova SB, Taneva SG, Krastev RBulgarian Chemical Communications. 2016 April; 48: 23 - 28.
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Foam Stabilized by Fly Ash Nanoparticles for Enhancing Oil RecoveryEftekhari AA, Krastev R, Farajzadeh RIndustrial & Engineering Chemistry Research. 2015; 54(50): 12482-12491.
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Neutron reflectometry on samples with curved geometryFrueh J, Ruehm A, Moehwald H, Krastev RJoint Annual Report of the MLZ and FRM II: 104.
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Reflectometry on curved interfacesFrueh J, Ruehm A, Moehwald H, Krastev R, Koehler RPhysica B: Condensed Matter.2015 Jan 15; 457: 202-211.
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Interactions in lipid stabilised foam filmsToca-Herrera JL, Krasteva N, Muller HJ, Krastev RAdv Colloid Interface Sci. 2014 May;207:93-106. doi: 10.1016/j.cis.2014.02.016. Epub 2014 Feb 22.
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Polyelectrolyte Multilayers as Functional Coatings for Controlled Biomolecular InteractionsXiong X, Hossfeld S, Margutti S, Krastev R2014. in: Biofunctional Surface Engineering, Pan Stanford Publishing; Auflage 1, Chapter 4: 47-69.
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Surface relaxations as a tool to distinguish the dynamic interfacial properties of films formed by normal and diseased meibomian lipidsGeorgiev GA, Yokoi N, Ivanova S, Tonchev V, Nencheva Y, Krastev RSoft Matter. 2014 Aug 14;10(30):5579-88. doi: 10.1039/c4sm00758a.
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Metallic oxide nanoparticles stimulate blood coagulation independent of their surface chargeSteuer H, Krastev R, Lembert NJ Biomed Mater Res B Appl Biomater. 2014 Jul;102(5):897-902. doi: 10.1002/jbm.b.33051. Epub 2013 Dec 18.
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Polyelectrolyte Coatings for Surfaces ModificationHossfeld S, Xiong X, Krastev RWOMag. 2013 Feb: 22.
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Hyaluronic acid / chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexesHartmann H, Hossfeld S, Schlosshauer B, Mittnacht U, Pego AP, Dauner M, Doser M, Stoll D, Krastev RJ Control Release. 2013 Apr 4;168(3):289-297. doi: 10.1016/j.jconrel.2013.03.026.
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Bioactive coronary stent coating based on layer-by-layer technology for siRNA releaseHossfeld S, Nolte A, Hartmann H, Recke M, Schaller M, Walker T, Kjems J, Schlosshauer B, Stoll D, Wendel HP, Krastev RActa Biomater. 2013 May; 9(5): 6741-6752. doi: 10.1016/j.actbio.2013.01.013.
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Impact of polyelectrolytes and their corresponding multilayers to human primary endothelial cellsNolte A, Hossfeld S, Schroeppel B, Mueller A, Stoll D, Walker T, Wendel HP, Krastev RJ Biomater Appl. 2013; 28 (1): 84-99. doi: 10.1177/0885328212437610
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Foam-oil interaction in porous media: implications for foam assisted enhanced oil recoveryFarajzadeh R, Andrianov A, Krastev R, Hirasaki GJ, Rossen WRAdv Colloid Interface Sci. 2012 Nov 15;183-184:1-13. doi: 10.1016/j.cis.2012.07.002. Epub 2012 Jul 31.
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Thermodynamic studies on thin liquid films IV. Foam film stabilized by sodium dodecyl sulfateIyota H, Ikeda N, Krastev RJ Colloid Interface Sci. 2011 Dec 1;364(1):170-7. doi: 10.1016/j.jcis.2011.08.035. Epub 2011 Aug 22.
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Foam films as thin liquid gas separation membranesRamanathan M, Muller HJ, Mohwald H, Krastev RACS Appl Mater Interfaces. 2011 Mar;3(3):633-7. Epub 2011 Feb 11. doi: 10.1021/am101126n.
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Effect of gas type on foam film permeability and its implications for foam flow in porous mediaFarajzadeh R, Muruganathan RM, Rossen WR, Krastev RAdv Colloid Interface Sci. 2011 Oct 14;168(1-2):71-8. doi: 10.1016/j.cis.2011.03.005. Epub 2011 Mar 24.
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Surface Chemistry Study of the Interactions of Benzalkonium Chloride with Films of Meibum, Corneal Cells Lipids, and Whole TearsGeorgiev GA, Yokoi N, Koev K, Kutsarova E, Ivanova S, Kyumurkov A, Jordanova A, Krastev R, Lalchev ZInvest Ophthalmol Vis Sci. 2011 June. Investigative Ophthalmology & Visual Science. June 2011; 52(7): 4645-4654. doi:10.1167/iovs.10-627
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Liquid- or solid-like behavior of [omim][BF4] at a solid interface?Köhler R, Restolho J, Krastev R, Shimizu K, Canoniga Lopes J, Saramago BJ. Phys. Chem. Lett. 2011(2): 1551-1555.
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Basic properties of foam films stabilized with tetraethyl ammonium salt of perfluoro octane sulfonate (PFOS)Ramanathan M, Mueller HJ, Vedula K, Mohwald H, Krastev RColloids Surf A Physicochem. 2010 Feb; 354 (1-3): 1-7. DOI: 10.1016/j.colsurfa.2009.11.032
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Interactions of Meibomian gland secretion with polar lipids in Langmuir monolayersGeorgiev GA, Kutsarova E, Jordanova A, Krastev R, Lalchev ZColloids Surf B Biointerfaces. 2010 Jul 1;78(2):317-27. Epub 2010 Mar 30. doi: 10.1016/j.colsurfb.2010.03.024
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Schaumzerstörung und Schaumverhinderung: Der Wirkmechanismus von Simeticon in vitroDittrich M, Miederer SE, Havertz B, Krastev RJ Gastroenterol Hepatol Erkr. 2010; 8(3): 19-25.
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Dynamics of thinning of foam films stabilized by n-dodecyl-beta-maltosideStockle S, Blecua P, Mohwald H, Krastev RLangmuir. 2010 Apr 6;26(7):4865-72. doi: 10.1021/la9036748.
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Changes of the molecular structure in polyelectrolyte multilayers under stressFruh J, Kohler R, Mohwald H, Krastev RLangmuir. 2010 Oct 5;26(19):15516-22. doi: 10.1021/la1015324.
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The formation of lipid bilayers on surfacesGromelski S, Saraiva AM, Krastev R, Brezesinski GColloids Surf B Biointerfaces. 2009 Dec 1;74(2):477-83. doi: 10.1016/j.colsurfb.2009.08.006. Epub 2009 Aug 12.
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Neue Erkenntnisse zum Wirkmechanismus von SimeticonDittrich M, Havertz B, Krastev R, Miederer ZPharmazeutische Zeitung (PZ). 2009; 41: 86.
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Absorption of Light and Heavy Water Vapours in Polyelectrolyte Multilayer FilmsDelajon C, Gutberlet T, Mohwald H, Krastev RColloids Surf B Biointerfaces. 2009 Dec 1;74(2):462-7. doi: 10.1016/j.colsurfb.2009.08.051. Epub 2009 Sep 8.
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Neutron Reflectometry Study of Swelling of Polyelectrolyte Multilayers in Water Vapours: Influence of Charge Density of the PolycationKohler R, Donch I, Ott P, Laschewsky A, Fery A, Krastev RLangmuir. 2009 Oct 6;25(19):11576-85. doi: 10.1021/la901508w
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Ordering of Fe3O4 Nanoparticles in Polyelectrolyte Multilayer FilmsKolasinska M, Gutberlet T, Krastev RLangmuir. 2009 Sep 1;25(17):10292-7. DOI: 10.1021/la9011185