Dr. Martin Stelzle

since Jan 2000   Head of BioMEMS & Sensors group

1996 - 2000  Senior Scientist, NMI, Dept. Applied Physics

1995 - 1996   Postdoc, Max-Planck Institute for Colloid and Interface Sciences, Berlin

1992-1994   Postdoc, IBM Almaden Research Center, San Jose, USA,
Polymer Science & Technology Department

1992   Ph.D. thesis, Technical University of Munich, Biophysics Institute, Prof. E. Sackmann;

1982-1988   Physics study at the University of Erlangen and the Technical University of Munich
Dr. Martin Stelzle
Group Leader BioMEMS and sensors
Diplom-Physiker

Projects

Publications

  • HepaChip-MP – a twenty-four chamber microplate for a continuously perfused liver coculture model
    Busche M, Tomilova O, Schütte J, Werner S, Beer M, Groll N, Hagmeyer B, Pawlak M, Jones P D, Schmees C, Becker H, Schnabel J, Gall K, Hemmler R, Matz-Soja M, Damm G, Beuck S, Klaassen T, Moer J, Ullrich A, Runge D, Schenke-Layland K, Gebhardt R und Stelzle M
    Lab on a Chip, DOI: 10.1039/d0lc00357c
  • Multimodal Chemosensor-Based, Real-Time Biomaterial/Cell Interface Monitoring
    Kubon M, Hartmann H, Moschallski M, Burkhardt C, Link G, Werner S, Stelzle M
    Advanced Biosystems. 2018; 2(6):1700236.
  • Measurement of temperature dependent heat flow rate from human limbs towards thermoelectric cooling device
    Link G, Stelzle M
    Med Devices Diagn Eng. 2017; 2(1): 72-74.
  • A novel microfluidic 3D platform for culturing pancreatic ductal adenocarcinoma cells: comparison with in vitro cultures and in vivo xenografts
    Beer M, Kuppalu N, Stefanini M, Becker H, Schulz I, Manoli S, Schuette J, Schmees C, Casazza A, Stelzle M, Arcangeli A
    Sci Rep. 2017 Apr 25;7(1):1325. doi: 10.1038/s41598-017-01256-8.
  • Auf Herz und Nieren prüfen
    Hagmeyer B, Becker H, Werner S, Stelzle M (2016).
    Physik Journal. 2016; 10:31
  • Introduction to polymer-based solid-contact ion-selective electrodes-basic concepts, practical considerations, and current research topics
    Bieg C, Fuchsberger K, Stelzle M
    Anal Bioanal Chem. 2017 Jan;409(1):45-61. doi: 10.1007/s00216-016-9945-6. Epub 2016 Oct 1.
  • Expanding an efficient, electrically driven and CNT-tagged P450 system into the third dimension: a nanowired CNT containing and enzyme stabilising 3D sol-gel electrode
    Llaudet E, Darimont D, Samba R, Matiychyn I, Stelzle M, Weissenborn MJ, Hauer B (2016).
    Chembiochem. 2016 Jul 15;17(14):1367-73. doi: 10.1002/cbic.201600173. Epub 2016 Jun 17.
  • Can Nanofluidic Chemical Release Enable Fast, High Resolution Neurotransmitter-Based Neurostimulation?
    Jones PD, Stelzle M
    Front Neurosci. 2016 Mar 31;10:138. doi: 10.3389/fnins.2016.00138. eCollection 2016.
  • Electrochemical etching of micro-pores in medical grade cobalt–chromium alloy as reservoirs for drug eluting stents
    Fuchsberger K, Binder K, Burkhardt C, Freudigmann Ch, Herrmann M, Stelzle M
    J Mater Sci Mater Med. 2016 Mar;27(3):47. doi: 10.1007/s10856-015-5660-7. Epub 2016 Jan 12.
  • Towards plug and play filling of microfluidic devices by utilizing networks of capillary stop valves
    Hagmeyer B, Zechnall F, Stelzle M
    Biomicrofluidics. 2014 Sep 19;8(5):056501. doi: 10.1063/1.4896063. eCollection 2014 Sep.
  • Organ-Like Cell Cultures in Microfluidic Systems
    Li D, Schütte J, Stelzle M
    2015 in: Li D. (eds) Encyclopedia of Microfluidics and Nanofluidics. Springer, New York, NY.
  • Application of PEDOT-CNT Microelectrodes for Neurotransmitter Sensing
    Samba R, Fuchsberger K, Matiychyn I, Epple S, Kiesel L, Stett A, Schuhmann W, Stelzle M
    Electroanalysis. 2014 March; 26(3): 548-555. https://doi.org/10.1002/elan.201300547
  • Chemische und physikalische Analyse eines ionenleitfähigen Terpolymers für die elektrochemische Sensorik
    Bieg, C
    Master-Thesis. Fakultät Angewandte Chemie, Hochschule Reutlingen. 2013. 53 Seiten.
  • Impedanzsensorik in mikrofluidischen Zellkultursystemen
    Spoo M
    Bachelor-Thesis. Fakultät Mechatronik/Elektrotechnik, Hochschule Esslingen. 2013. 94 Seiten.
  • Rastmechanik zur Aufnahme und Fixierung von Mikrofluidiksystemen
    Li A
    Bachelor-Thesis. Studiengang Medizintechnik, Jade Hochschule, Wilhelmshaven. 2013. 81 Seiten.
  • Is the Enhanced Adhesion of PEDOT Thin Films on Electrodes Due to Sulfur - Gold Interaction? - An XPS Study
    Samba R, Chassé T, Stelzle M
    The Open Surface Science Journal. 2013; 5: 17-20.
  • PEDOT–CNT composite microelectrodes for recording and electrostimulation applications: fabrication, morphology, and electrical properties
    Gerwig R, Fuchsberger K, Schroeppel B, Link GS, Heusel G, Kraushaar U, Schuhmann W, Stett A, Stelzle M
    Front Neuroeng. 2012; 5: 8. Published online 2012 May 4. doi: 10.3389/fneng.2012.00008
  • Towards quantification of biocompatibility: Monitoring ingrowth behavior of biomaterials in tissue with a microsensor implant
    Kubon M, Moschallski M, Ensslen T, Link G, Werner S, Burkhardt C, Hartmann H, Schlosshauer B, Urban G, Stelzle M
    IEEE Conference Paper, 2011, doi: 10.1109/TRANSDUCERS.2011.5969289
  • Numerical modelling and measurement of cell trajectories in 3-D under the influence of dielectrophoretic and hydrodynamic forces
    Holzner F, Hagmeyer B, Schütte J, Kubon M, Angres B, Stelzle M
    Electrophoresis. 2011 August; 32(17): 2366-2376. DOI 10.1002/elps.201100026
  • A microsensor system to probe physiological environments and tissue response
    Kubon M, Moschallski M, Link G, Ensslen T, Werner S, Burkhardt C, Nisch W, Scholz B, Schlosshauer B, Urban G, Stelzle M
    IEEE Conference Paper, 2010, doi: 10.1109/TRANSDUCERS.2011.5969289
  • Artificial microorgans: a microfluidic tool for in vitro assessment of toxicity
    Schütte J, Stelzle M
    Bioanalysis. 2011; 3(21): 2373-2375. DOI 10.4155/bio.11.230
  • "Artificial micro organs"-a microfluidic device for dielectrophoretic assembly of liver sinusoids
    Schutte J, Hagmeyer B, Holzner F, Kubon M, Werner S, Freudigmann C, Benz K, Bottger J, Gebhardt R, Becker H, Stelzle M
    Biomed Microdevices. 2011 Jun;13(3):493-501. doi: 10.1007/s10544-011-9517-7.
  • Towards implantable sensors and actuators (Part 1): A microsensor device to probe biological and physiological environments
    Kubon M, Moschallski M, Werner S, Link G, Burkhardt C, Nisch W, Urban G & Stelzle M
    Biomedizinische Technik / Biomedical Engineering (2010), 10.1515/bmt.2010.711
  • Towards implantable sensors and actuators (Part 2): Avian ex ovo culture as quasi-in vivo environment
    Kubon M, Moschallski M, Link G, Werner S, Burkhardt C, Nisch W, Scholz B, Schlosshauer B, Urban G & Stelzle M
    Biomedizinische Technik / Biomedical Engineering (2010), 10.1515/bmt.2010.520
  • Ex ovo culture: An in vivo model for microsensorarray implants
    Kubon M, Moschallski M, Link GS, Werner S, Burkhardt C, Nisch W, Scholz B, Schlosshauer B, Urban G, Stelzle M
    7th International Meeting on Substrate-Integrated Microelectrode Arrays Reutlingen, 2010, NMI, BioPro.
  • MicroPrep: chip-based dielectrophoretic purification of mitochondria
    Moschallski M, Hausmann M, Posch A, Paulus A, Kunz N, Duong TT, Angres B, Fuchsberger K, Steuer H, Stoll D, Werner S, Hagmeyer B, Stelzle M
    Electrophoresis. 2010 Aug;31(15):2655-63. doi: 10.1002/elps.201000097.
  • From Bioseparation to "Artificial Micro Organs" - microfluidic chip based particle manipulation techniques
    Stelzle M (2010)
    Microfluidics, BioMEMS, and Medical Microsystems VIII. 2010 Feb; 7593: 75930G.
  • Chemical stimulation of adherent cells by localized application of acetylcholine from a microfluidic system
    Zibek S, Hagmeyer B, Stett A, Stelzle M
    Front Neuroeng. 2010 Nov 26;3:113. doi: 10.3389/fneng.2010.00113. eCollection 2010.
  • A method for patterned in situ biofunctionalization in injection-molded microfluidic devices
    Schuette J, Freudigmann C, Benz K, Bottger J, Gebhardt R, Stelzle M
    Lab Chip. 2010 Oct 7;10(19):2551-8. doi: 10.1039/c005307d. Epub 2010 Jul 30.
  • Micro- and Nanopatterning of Surfaces Employing Self Assembly of Nanoparticles and Its Application in Biotechnology and Biomedical Engineering
    Burkhardt C, Fuchsberger K, Nisch W, Stelzle M
    Lithography. M. Wang. 2010. Wien, IN-TECH: 629-644.
  • Chemical stimulation of cells – microsystem, experiment & modelling
    Zibek S, Hagmeyer B, Stett A, Stelzle M
    Proceedings MEA Meeting 2008, Reutlingen, BioPro edition, Vol.5, p.266-269, ISBN 3-938345-05-5
  • Localized functional chemical stimulation of TE 671 cells cultured on nanoporous membrane by calcein and acetylcholine.
    Zibek S, Stett A, Koltay P, Hu M, Zengerle R, Nisch W, Stelzle M
    Biophys J. 2007 Jan 1;92(1):L04-6. Epub 2006 Nov 3. DOI: 10.1529/biophysj.106.096743
  • Low temperature adhesion bonding for BioMEMS
    Kentsch J, Breisch S, Stelzle M
    Journal of Micromechanics and Microengineering. 2006 March; 16 (4): 802-807.
  • Accumulation and trapping of hepatitis A virus particles by electrohydrodynamic flow and dielectrophoresis
    Grom F, Kentsch J, Muller T, Schnelle T, Stelzle M
    Electrophoresis. 2006 Apr;27(7):1386-93. DOI: 10.1002/elps.200500416
  • Measuring single-bond rupture forces using high electric fields in microfluidic channels and DNA oligomers as force tags.
    Breisch S, Gonska J, Deissler H, Stelzle M
    Biophys J. 2005 Sep;89(3):L19-21. Epub 2005 Jul 22. DOI: 10.1529/biophysj.105.066795
  • Selective chemical surface modification of fluidic microsystems and characterization studies
    Breisch S, de Heij B, Löhr M, Stelzle M
    J. Micromechanics and Microengineering. 2004 Jan; 14(4): 497-505.
  • Microdevices for manipulation and accumulation of micro- and nanoparticles by dielectrophoresis.
    Dürr M, Kentsch J, Muller T, Schnelle T, Stelzle M
    Electrophoresis. 2003 Feb;24(4):722-31. DOI: 10.1002/elps.200390087
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