Dr. Günther Zeck

Research interests  

Neurotechnologies and applications

  • CMOS - based neurochips
            Parallel detection of neuronal activity with 16000 sensors
            Capacitive stimulation of neuronal activity with capacitor arrays
            Tissue analysis - chip coupling
  • multi-electrode arrays
            Neuronal cell cultures (rat)
            Electrical stimulation
  • retina
            Detection/analysis of extracellular activity in rabbit, rat and mouse retinas
            Detection/analysis of single cell activity and field potentials in blind retinas
            Electrical stimulation of healthy and blind retinas

Curriculum vitae

Group leader at the NMI since 2010

2006 - 2010 Senior Postdoc, Max Planck Inst. Neurobiology, Martinsried

2003 - 2005 Postdoctoral researcher at Mass. General Hospital & Harvard Medical School, Boston, USA.

1998-2002 Dr. rer. nat., Biophysics, TU Munich & Max Planck Inst. Biochemistry

1992 - 1998 Physics studies at the TU Munich

Teachings

Graduate School of Neural Information Processing, Bernstein Centre Tübingen

Dr. Günther Zeck

Group Leader Neurophysics
Diplom-Physiker
T +49 (0)7121 51530-807
F +49 (0)7121 51530-62

Publications

  • Electrode-size dependent thresholds in subretinal neuroprosthetic stimulation
    Corna A, Herrmann T, Zeck G.
    J Neural Eng. 2018 Aug;15(4):045003. doi: 10.1088/1741-2552/aac1c8. Epub 2018 May 2.
  • Functional characterization of the retinal output upon optogenetic stimulation
    M Reh, M Kriebel, R Thewes and G Zeck
    MEA Meeting 2018; Reutlingen, Deutschland. doi:10.3389/conf.fncel.2018.38.00045
  • Combining two photon microscopy and CMOS MEA to uncover the mechanism of aberrant activity in blind retina
    Lee M-J, Srivastava P, Rogerson L, Berens P, Euler T, Schubert T, Zeck G
    MEA Meeting 2018, 10.3389/conf.fncel.2018.38.00022, 2018
  • Evaluation of short pulse laser damage to the retinal pigment epithelium layer
    Ramos S, Reh M, Zeck G, Heussner N
    Biophotonics: Photonic Solutions for Better Health Care VI. 2018 April; 10685.
  • A spike sorting toolbox for up to thousands of electrodes validated with ground truth recordings in vitro and in vivo
    Yger P, Spampinato GLB, Esposito E, Lefebvre B, Deny S, Gardella C, Zeck G, Picaud S, Duebel J, Marre O
    Elife. 2018 Mar 20;7. pii: e34518. doi: 10.7554/eLife.34518.
  • Investigation of the functional retinal output using Microelectrode arrays
    Zeck G
    Methods Mol Biol. 2018;1695:81-88. doi: 10.1007/978-1-4939-7407-8_8.
  • Subretinal electrical stimulation reveals intact network activity in the blind mouse retina
    Stutzki H, Helmhold F, Eickenscheidt M, Zeck G
    J Neurophysiol. 2016 Oct 1;116(4):1684-1693. doi: 10.1152/jn.01095.2015. Epub 2016 Jul 13.
  • Unsupervised neural spike sorting for high-density microelectrode arrays with convolutive independent component analysis
    Leibig C, Wachtler T, Zeck G
    J Neurosci Methods. 2016 Sep 15;271:1-13. doi: 10.1016/j.jneumeth.2016.06.006. Epub 2016 Jun 15.
  • Electrochemical noise and impedance of Au electrode/electrolyte interfaces enabling extracellular detection of glioma cell populations
    Rocha PR, Schlett P, Kintzel U, Mailander V, Vandamme LK, Zeck G, Gomes HL, Biscarini F, de Leeuw DM
    Sci Rep. 2016 Oct 6;6:34843. doi: 10.1038/srep34843.
  • Visualizing Epithelial-Mesenchymal Transition Using the Chromobody Technology
    Maier J, Traenkle B, Rothbauer U
    Cancer Res. 2016 Oct 1;76(19):5592-5596. Epub 2016 Sep 15.
  • PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities
    Samba R, Herrmann T, Zeck G
    J Neural Eng. 2015 Feb;12(1):016014. doi: 10.1088/1741-2560/12/1/016014. Epub 2015 Jan 14.
  • Aberrant activity in degenerated retinas revealed by electrical imaging
    Zeck G
    Frontiers in Cellular Neuroscience. 2016; 10 :15. doi: 10.3389/fncel.2016.00025
  • Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia
    Schultheiss M, Schnichels S, Hermann T, Hurst J, Feldkaemper M, Arango-Gonzalez B, Ueffing M, Bartz-Schmidt KU, Zeck G, Spitzer MS
    PLoS One. 2016 Feb 5;11(2):e0148616. doi: 10.1371/journal.pone.0148616. eCollection 2016.
  • PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities
    Samba R, Herrmann T, Zeck G
    J Neural Eng. 2015 Feb;12(1):016014. doi: 10.1088/1741-2560/12/1/016014. Epub 2015 Jan 14.
  • Daylight vision repair by cell transplantation
    Santos-Ferreira T, Postel K, Stutzki H, Kurth T, Zeck G, Ader M
    Stem Cells. 2015 Jan; 33(1):79-90. doi: 10.1002/stem.1824.
  • Rhythmic Ganglion Cell Activity in Bleached and Blind Adult Mouse Retinas
    Menzler J, Channappa L, Zeck G
    PLoS One. 2014 Aug 25;9(8):e106047. doi: 10.1371/journal.pone.0106047. eCollection 2014.
  • Action potentials in retinal ganglion cells are initiated at the site of maximal curvature of the extracellular potential
    Eickenscheidt M, Zeck G
    J Neural Eng. 2014 Jun;11(3):036006. doi: 10.1088/1741-2560/11/3/036006. Epub 2014 Apr 24.
  • Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury
    Stutzki H, Leibig C, Andreadaki A, Fischer D, Zeck G
    Front Cell Neurosci. 2014; 8: 38. doi: 10.3389/fncel.2014.00038
  • Axonale Leitungsgeschwindigkeiten in der Kaninchenretina gemessen mit Multitransistorarray
    Thoma M
    Diplomarbeit. Physik-Department, Technische Universität München. 2012. 61 Seiten.
  • A Comprehensive Small Interfering RNA Screen Identifies Signaling Pathways Required for Gephyrin Clustering
    Wuchter J, Beuter S, Treindl F, Herrmann T, Zeck G, Templin MF, Volkmer H
    The Journal of Neuroscience. 2012 Oct 17; 32(42):14821–14834
  • Electrical stimulation of retinal neurons in epiretinal and subretinal configuration using a multicapacitor array
    Eickenscheidt M, Jenkner M, Thewes R, Fromherz P, Zeck G
    J Neurophysiol. 2012 May;107(10):2742-55. Epub 2012 Feb 22.
  • Extracellular voltage noise probes the interfaces between retina and silicon chip
    Zeitler R, Fromherz P, Zeck G
    Applied Physics Letters. 2011 Dec; 99: 263702. DOI 10.1063/1.3672224
  • Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response
    Zeck G, Lambacher A, Fromherz P
    PLoS One. 2011;6(6):e20810. Epub 2011 Jun 2.
  • Network oscillations in rod-degenerated mouse retinas
    Menzler J, Zeck G
    J Neurosci. 2011 Feb 9;31(6):2280-91. DOI: 10.1523/JNEUROSCI.4238-10.2011