People

Marielise Achmakidou
Office / Reception
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Nicole Anderle
PhD Student Tumor Biology
T +49 (0)7121 51530-867
F +49 (0)7121 51530-62
Elsa Arefaine
Technical Assistant Regenerative Biomaterials
T +49 (0)7121 51530-827
F +49 (0)7121 51530-62
Steffen Baier
Technician
T +49 (0)7121 51530-42
F +49 (0)7121 51530-16
Maximilian Becker
PhD Student Applied Materials Science and Electron Microscopy
T +49 (0)7121 51530-908
F +49 (0)7121 51530-62
Dr.-Ing. Meike Beer
Scientist BioMEMS and Sensors
T +49 (0)7121 51530-899
F +49 (0)7121 51530-62

Areas of activity

Microfluidics for applications as Lab on a Chip, for separation of biological particles, sample preparation in microfluidics systems, joining technologies for microfluidics, integration of electrodes in microfluidics.

Stages of career

Since 2007 Research associate in the group BioMEMS and Sensor Technology

2007 PhD in microsystems technology on immobilization of proteins in hydrogel microarrays on polymer substrates

2003-2007 Scientific assistant at the Chair of Chemistry and Physics of Interfaces, Institute for Microsystems Technology, University of Freiburg

1998-2003 Studied microsystems technology at the University of Freiburg.

 

Dr. Antje Biesemeier
Scientist Applied Materials Science and Electron Microscopy
T +49 (0)7121 51530-909
F +49 (0)7121 51530-62

Arbeitsgebiete

Präparation und Anwendung in der Elektronenmikroskopie (Bildgebung und Analytik) zu Fragestellungen aus den Bereichen
-    biologisch-technische Grenzflächen
-    3D-Ultrastruktur von Zellen und Geweben

Projekte im Rahmen der experimentellen Augenheilkunde:
-    multimodales Imaging von Spendermaterial und Modellsystemen zur Erforschung der altersbedingten Makuladegeneration (SLO/OCT, Immunhistologie, EM)
-    Erforschung der Rolle der Pigmentierung bei Schwermetallassoziierter Neurodegeneration


Aktuelle Position


Seit 05/2018    Wissenschaftliche Mitarbeiterin in der Gruppe Angewandte Materialwissenschaften und Elektronenmikroskopie am NMI
Seit 10/2010    Wissenschaftliche Mitarbeiterin in der Sektion für Experimentelle Vitreoretinale Chirurgie, Department für Augenheilkunde, Universitätsklinikum (UKT) Tübingen, Deutschland.


Beruflicher Werdegang

 
2018     Habilitation im Fachbereich Experimentelle Ophthalmologie
Titel: „Characterisation of eyes affected by age related macular degeneration using high resolution (analytical) imaging techniques.“ durchgeführt am Department für Augenheilkunde und dem Institut für Angewandte Physik Tübingen
 
2010    Promotion (Dr. rer. nat.)
Titel „Ultrastrukturelle Untersuchung der Melanogenese im adulten humanen retinalen Pigmentepithel nach adenoviraler Transduktion mit dem Tyrosinasegen“; durchgeführt am Department für Augenheilkunde Tübingen
 
2004    Biologie-Diplom, Universität Erlangen.
 

10 most important peer reviewed publications


•    Taubitz T, Tschulakow AV, Tikhonovich M, Illing B, Fang Y, Biesemeier A, Julien-Schraermeyer S, Schraermeyer U. Ultrastructural alterations in the retinal pigment epithelium and photoreceptors of a Stargardt patient and three Stargardt mouse models: indication for the central role of RPE melanin in oxidative stress. PeerJ. 2018 Jul 19;6:e5215..
•    Biesemeier A, Eibl O, Eswara S, Audinot JN, Wirtz T, Schraermeyer U. Transition metals and trace elements in the retinal pigment epithelium and choroid: correlative ultrastructural and chemical analysis by analytical electron microscopy and nano-secondary ion mass spectrometry. Metallomics. 2018 Feb 21;10(2):296-308.
•    Biesemeier A, Eibl O, Eswara S, Audinot JN, Wirtz T, Pezzoli G, Zucca FA, Zecca L, Schraermeyer U. Elemental mapping of Neuromelanin organelles of human Substantia Nigra: correlative ultrastructural and chemical analysis by analytical transmission electron microscopy and nano-secondary ion mass spectrometry. J Neurochem. 2016 Jul;138(2):339-53.
•    Biesemeier A, Yoeruek E, Eibl O, Schraermeyer U. Iron accumulation in Bruch's membrane and melanosomes of donor eyes with age-related macular degeneration. Exp Eye Res. 2015 Aug;137:39-49.
•    Leal SS, Cristóvaõ, JS, Biesemeier A, Cardoso I, and Gomes D. Aberrant Q1 Q2 zinc binding to immature conformers of metal-free copper–zinc superoxide dismutase triggers amorphous aggregation. Metallomics. 2015 Feb;7(2):333-46.
•    Biesemeier A, Taubitz T, Julien S, Yoeruek E, Schraermeyer U. Choriocapillaris breakdown precedes retinal degeneration in age-related macular degeneration. Neurobiol Aging. 2014 May 10. pii: S0197-4580(14)00341-8.
•    Julien, S*, Biesemeier, A*, Kokkinou, D, Eibl, O, Schraemeyer, U. Zinc deficiency leads to lipofuscin accumulation in the retinal pigment epithelium of pigmented rats. PLoS ONE. 2011 6(12): e29245. *both authors contributed equally to this work.
•    Biesemeier A, Schraermeyer U, Eibl O. Chemical composition of melanosomes, lipofuscin and melanolipofuscin granules of human RPE tissues. Exp Eye Res. 2011 Jul; 93(1):29-39. Epub 2011 Apr 16.
•    Biesemeier A, Eibl O, Schraermeyer U. Quantitative chemical analysis of ocular melanosomes in stained and non-stained tissues. Micron. 2011 Jul; 42(5):461-70. Epub 2011 Jan 25.
•    Biesemeier A, Kreppel F, Kochanek S, Schraermeyer U. The classical premelanosome, known from prenatal melanogenesis, is not essential for melanisation in adult RPE. Cell Tissue Res. 2010 Mar; 339(3):551-60.

 
Florian Billing
PhD Student Interface Immunology
T +49 (0)7121 51530-945
F +49 (0)7121 51530-62
Team Bistro
Bistroteam
T +49 (0)7121 51530-18
F +49 (0)7121 51530-62
Dr. Eva-Maria Brauchle
Scientist Applied Materials Science and Electron Microscopy
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62

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Monika Braun
Receptionist
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Ewa Breitinger
Engineer Assay Development
T +49 (0)7121 51530-818
F +49 (0)7121 51530-62

Areas of activity

Application of miniaturized parallel immunoassays and reverse-phase protein arrays (RPA). Characterization and validation of antibodies. Studies for development and service projects with customers and partners from the pharmaceutical industry and clinical research.

Stages of career

since 2009 Employee at the NMI, Reutlingen, Germany

2004 - 2009 Boehringer Ingelheim GmbH & Co. KG, Biberach a.d.R.

2000 - 2004 Study of chemistry, Reutlingen University of Applied Sciences

 

Sandra Buckenmaier
Scientist Electrophysiology
T +49 (0)7121 51530-883
F +49 (0)7121 51530-62

Hier ist ein wenig text

Dr. Claus J. Burkhardt
Group Leader Applied Materials Science and Electron Microscopy
T +49 (0)7121 51530-55
F +49 (0)7121 51530-62

Areas of activity
Nanotechnology, nanolithography with electron and ion beams, electron beam and ion beam induced material deposition (additive nanolithography), electron microscopy, development of preparation methods, thin film technology, microsystems technology

Stages of career
2018 - today Group Leader Applied Materials Science and Electron Microscopy

2008 - 2017 Group Leader Microsystems and Nanotechnology 

1998 - 2007 Research Associate at the NMI, Project Manager

1995 - 1997 Research assistant at the Hearing Research Centre Tübingen

1997   Doctorate at the University of Tübingen

1986 - 1992 Research Assistant, PhD Student, University of Tübingen, Institute of Applied Physics

1979 - 1986 Physics studies, University of Tübingen

Marius Busche
PhD student BioMEMS and Sensors
T +49 (0)7121 51530-832
F +49 (0)7121 51530-62
Viviana Carcamo Yañez
Scientist Biochemistry
T +49 (0)7121 51530-837
F +49 (0)7121 51530-62

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Dr. Paolo Cesare
Group Leader Neuromicrophysiological Systems
T +49 (0)7121 51530-826
F +49 (0)7121 51530-16

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Andrea Corna
PhD student Neurophysics
T +49 (0)7121 51530-892
F +49 (0)7121 51530-62

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Clara Daab
Scientist Biomedical Micro and Nano Engineering
T +49 (0)7121 51530-477
F +49 (0)7121 51530-62
Ruben Daum
PhD Student Biomaterials Engineering
T +49 (0)7121 51530-414
F +49 (0)7121 51530-62

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Oliver Davidovic
IT
T +49 (0)7121 51530-33
F +49 (0)7121 51530-62
Dr. Ulf Dettinger
Scientist Interface Analytics in Production Processes
T +49 (0)7121 51530-72
F +49 (0)7121 51530-62

Arbeitsgebiete:

liegen im Bereich der Oberflächenanalytik (HRXPS, auch in Kombination mit Gas Cluster Ion Beams (GCIB) sowie FTIR-Mikroskopie) und hierbei im Besonderen in der Reinigungsvalidierung, der Untersuchung von Passivierungsschichten, sowie der Prozessanalytik


Werdegang mit den wichtigsten Stationen

Seit 2019  Wissenschaftler in der Arbeitsgruppe Grenzflächenanalytik im Produktionsprozess

2017-2018  Wissenschaftler in der Arbeitsgruppe Grenzflächen- und Mikrostrukturanalytik

2010-2017  Promotion in der Physikalischen Chemie über organische Solarzellen

2004-2010  Studium der Chemie an der Universität Tübingen

 

Publikationen, die nicht am NMI entstanden sind:

Aygül, U.; Batchelor, D.; Dettinger, U.; Yilmaz, S.; Allard, S.; Scherf, U.; Peisert, H.; Chassé, T., Molecular Orientation in Polymer Films for Organic Solar Cells Studied by NEXAFS, J. Phys. Chem. C 2012, 116, 4870-4874.

Zorn, S.; Dettinger, U.; Skoda, M. W. A.; Jacobs, R. M. J.; Peisert, H.; Gerlach, A.; Chassé, T.; Schreiber, F., Stability of hexa(ethylene glycol) SAMs towards the exposure to natural light and repeated reimmersion, Appl. Surf. Sci. 2012, 258, 7882-7888.

Aygül, U.; Peisert, H.; Batchelor, D.; Dettinger, U.; Ivanovic, M.; Tournebize, A.; Mangold, S.; Forster, M.; Dumsch, I.; Kowalski, S.; Allard, S.; Scherf, U.; Chasse, T., Molecular orientation in polymer/fullerene blend films and the influence of annealing, Sol. Energy Mater. Sol. Cells 2014, 128, 119-125.

Dettinger, U.; Egelhaaf, H.-J.; Brabec, C. J.; Latteyer, F.; Peisert, H.; Chassé, T., FTIR Study of the Impact of PC[60]BM on the Photodegradation of the Low Band Gap Polymer PCPDTBT under O2 Environment, Chem. Mater. 2015, 27, 2299-2308.

Degler, D.; Barz, N.; Dettinger, U.; Peisert, H.; Chasse, T.; Weimar, U.; Barsan, N., Extending the toolbox for gas sensor research: Operando UV/vis diffuse reflectance spectroscopy on SnO2-based gas sensors, Sensors and Actuators B-Chemical 2016, 224, 256-259.

Ivanovic, M.; Aygül, U.; Dettinger, U.; Tournebize, A.; Polek, M.; Batchelor, D.; Mangold, S.; Forster, M.; Scherf, U.; Peisert, H.; Chasse, T., Electronic structure and self-organization properties of low band gap polymers: The effect of the introduction of additional thiophene moieties, Sol. Energy Mater. Sol. Cells 2016, 157, 286-294.

Batchelor, D. R.; Aygül, U.; Dettinger, U.; Ivanovic, M.; Tournebize, A.; Mangold, S.; Forster, M.; Scherf, U.; Peisert, H.; Chassé, T., Insight into the orientation of LBG polymer films by XANES experiment and calculation, Eur. Polym. J. 2016, 81, 686-693.

Dettinger, U. , Stabilität der aktiven Schicht organischer Solarzellen anhand des Modellsystems PCPDTBT:PC(60)BM, Dissertation

Ira Digel
Management Assistance
T +49 (0)7121 51530-37
F +49 (0)7121 51530-16
Anette Döttinger
Technical assistant Assay development
T +49 (0)7121 51530-814
F +49 (0)7121 51530-16

Auch hier wird Text ausgegeben

Christine Dürr
Technical assistant Molecular neurobiology
T +49 (0)7121 51530-77
F +49 (0)7121 51530-62
Dr. Eva Erne
Scientist Tumor biology
T +49 (0)7121 51530-868
Otto Euchner
T +49 (0)7121 51530-23
F +49 (0)7121 51530-62
Nora Feuerer
PhD student Biomaterials engineering
T +49 (0)7121 51530-414
F +49 (0)7121 51530-62

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Simon Fink
PhD student Assay development
T +49 (0)7121 51530-410
F +49 (0)7121 51530-62
Roswitha Fischer
Technical assistant Molecular neurobiology
T +49 (0)7121 51530-77
F +49 (0)7121 51530-62
Christian Freudigmann
Scientist Regenerative biomaterials
T +49 (0)7121 51530-846
F +49 (0)7121 51530-62

Areas of activity

- primary cell cultures (musculoskeletal cell types)
- Adhesion / Vitality Experiments
- assay-based characterization of the performance of cell biomaterial cultures 
- Identification of prognostic markers for autologous chondrocyte transplants

Stages of carees

Since 2008 Research Associate, Department of Regenerative Medicine II, NMI

2006 - 2007 Studies Biomedical Engineering (Master of Science) at the Albstadt-    Sigmaringen University of Applied Sciences

2002 - 2006 Study of Biotechnology (Bachelor of Engineering) at the Furtwangen University of Applied Sciences

 

Kai Fuchsberger
Scientist BioMEMS and sensors
T +49 (0)7121 51530-841
F +49 (0)7121 51530-62

Areas of activity

Surface modification and electrochemistry for sensor applications

Research interests

Surface Modifications, Electrochemical Sensors Detection Systems

 

2006 - 2009]   Further education in mathematics and physics and studies of nanobiotechnology, TU Kaiserslautern (DISC)

2006 - 2009    Further education in mathematics and physics and studies of nanobiotechnology, TU Kaiserslautern (DISC)

1999 - 2006 Dipl. Biologist, University of Bayreuth, Diploma thesis with Prof. Dr. Erwin Beck, Plant Physiology

on effects of artificial auxins on cell division and elongation growth of tobacco cell cultures

1999 Process control, Hoechst Trevira GmbH & Co KG in Bobingen

1996 - 1999   Apprenticeship as chemical laboratory assistant, Hoechst Trevira GmbH & Co KG, Bobingen , Germany

1995 - 1996    Studied Mathematics, University of Augsburg

 

Martin Gaier
Technical assistant Adhesive bonding and test engineering
T +49 (0)7121 51530-854
F +49 (0)7121 51530-62
Karin Gebhardt
Technical assistant Electrophysiology
T +49 (0)7121 51530-24
F +49 (0)7121 51530-62
Karin Gerlach
Technical assistant Interfaces and nanoanalytics
T +49 (0)7121 51530-823
F +49 (0)7121 51530-62
Michael Ghosh
PhD student Biochemistry
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Sibylle Glock
Technical assistant Molecular neurobiology
T +49 (0)7121 51530-77
F +49 (0)7121 51530-62
Dr. Jens Göpfert
Group Leader Biochemistry
T +49 (0)7121 51530-471
F +49 (0)7121 51530-62

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Marius Gramlich
PhD Bioanalytics
T +49 (0)7121 51530-817
F +49 (0)7121 51530-62
Dr. Richard Griesbach
Scientist Molecular neurobiology
T +49 (0)7121 51530-74
F +49 (0)7121 51530-62

Areas of activity

Generation of stable cell lines for pharmaceutical target validation. Application of third generation lentiviral expression systems. Further development of cell culture models for inflammatory and immunological research. 

stages of career

from 2013 Scientific assistant in the working group Target Expression Systems

2012-2013 Post-Doc at Helmholtz Zentrum München, Department of Cellular Signal Integration

2008-2012 PhD at Helmholtz Zentrum München on basic mechanisms of T cell activation

2007-2008 Diploma thesis on changes in gene expression profile in phenotypic modulation of smooth muscle cells

2002-2007 Study of Biochemistry at the Eberhard-Karls-University Tübingen and the Ludwig-Maximilian-University Munich

Jens Gruber
Technical assistant Biochemistry
T +49 (0)7121 51530-412
F +49 (0)7121 51530-62
Dr. Nadja Gugeler
Head of Public relations
T +49 (0)7121 51530-842
F +49 (0)7121 51530-16

seit April 2001: am NMI Reutlingen
1998 – 2001: IKP in Stuttgart (Dr. Margarete Fischer-Bosch-Institut für Klinische Pharmakologie)
Weiterbildung zur Biometrikerin
Biologiestudium und Promotion (Universität Tübingen)

Anna Günther
Scientist Biochemistry
T +49 (0)7121 51530-470
F +49 (0)7121 51530-62

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Sarah Haag
Administration
T +49 (0)7121 51530-11
F +49 (0)7121 51530-16
Britta Hagmeyer
Group Leader IT
T +49 (0)7121 51530-49
F +49 (0)7121 51530-62

Areas of activity

- Optimization during the development of microfluidic systems using numerical simulations

- Development of LabVIEW-based software, e.g. for the control of microfluidic components

Research interests

- Numerical simulations of physical phenomena in microfluidic systems, LabVIEW programming

Stages of career

Since 2018   Groupleader IT

2008-2018   Research associate in the group BioMEMS and Sensor Technology

2007 / 2008  Diploma thesis at the NMI in the group BioMEMS and Sensor Technology, implementation and simulation of physical models in FlexPDE® for the description of particle transport in liquids according to local application

1999 - 2008  Studied Bioinformatics at the Eberhard Karls University Tübingen

Prof. Dr. Hugo Hämmerle
Managing director NMI TT GmbH
T +49 (0)7121 51530-45
F +49 (0)7121 51530-16

Stages of career

since 2010 Speaker of the Innovation Alliance Baden-Württemberg innBW

since 2008 Managing Director NMI TT GmbH

2008-2018 Head of Institute NMI 

2003 Honorary Professorship, Faculty of Medicine, University of Tübingen

1998 Deputy Head of NMI Institute

1994 Visiting Scientist at Rush Presbyterian-St. Luke's Medical Center, Chicago, USA

since 1990 Head of the Life Sciences Department, NMI

since 1987 Research Associate, NMI

1987 Doctorate in Biochemistry, Physiological Institute, University of Tübingen

1982 Biologist, University of Hohenheim, Germany

1978 - 1982 Study of Biology and Chemistry, University of Hohenheim

1974 - 1978 Technician, Institute of Genetics, University of Hohenheim

Supervisory board activities

    Retina Implant AG Reutlingen, Deputy Chairman
    Tetec AG Reutlingen, Chairman

Julia Häring
PhD student Biochemistry
T +49 (0)7121 51530-412
F +49 (0)7121 51530-62
Ursula Härle
Technical assistant Molecular neurobiology
T +49 (0)7121 51530-848
F +49 (0)7121 51530-62
Eberhard Harm
Technician
T +49 (0)7121 51530-42
F +49 (0)7121 51530-16
Dr. Hanna Hartmann
Head of Dept. Biomedicine and Material Sciences
T +49 (0)7121 51530-872
F +49 (0)7121 51530-62

Research focus

    Medical devices and biocompatibility
    Coating / modification of surfaces: Regulation of the adhesion of proteins, bacteria, cells, etc.
    Immobilization and controlled release of active substances
    Characterization of surface properties and biological reactions

Curriculum vitae

since 2016 Group leader Regenerative Biomaterials, NMI, Reutlingen

2015-2016 Deputy Group Leader, Biomaterials, NMI, Reutlingen
Focus on medical devices, surface coating and analytics, biocompatibility

2013-2015 Project leader, Biomaterials Working Group, NMI, ReutlingeN
Topics. characterization/modification of surfaces for medical applications, polymer/polyelectrolyte coatings Characterization/modification of surfaces for medical applications, polymer/polyelectrolyte coatings, immobilization of biomolecules

2008-2013 Scientist, Working Group Regenerative Medicine I, NMI, ReutlingeN
Topics: fibrosis inhibition, nerve regeneration, RNAi nanoparticles for cell response control: Fibrosis inhibition, nerve regeneration, RNAi nanoparticles to control cell response, cell-specific addressing

2007-2008 Post-Doc, Institute for Medical Microbiology and Hygiene, University of Tübingen, Germany
Topics. Influences of bacteria on infected target cells, apoptosis inhibition and regulation of transcription factors Influences of bacteria on infected target cells, apoptosis inhibition and regulation of transcription factors 

2003-2006 PhD, Institute for Medical Microbiology and Hygiene, University of Tübingen, "Host cell response after bacterial infection: apoptosis inhibition by Bartonella henselae and HIF-1 activation by Enterobacteriaceae" (in German)

2002-2003 Diploma thesis, Chair of Biotechnology, University of Würzburg, Biocompatibility and Functionality Investigation of Biomaterial for Immunoisolated Transplantation of Mammalian Cells

1998-2002 Biology studies, University of Würzburg, Germany

Lisa Häsler
Scientist Biochemistry
T +49 (0)7121 51530-410
F +49 (0)7121 51530-62
Andreas Heid
PhD student Micromedical and surface engineering
T +49 (0)7121 51530-218
F +49 (0)7121 51530-62
Anne Heine
Scientist Biochemistry
T +49 (0)7121 51530-580
F +49 (0)7121 51530-62
Stefanie Heinlin
Office / Reception
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Willy Herb
T +49 (0)7121 51530-42
F +49 (0)7121 51530-16
Markus Herrmann
Technical assistant Biofunctionalized surfaces
T +49 (0)7121 51530-882
F +49 (0)7121 51530-16

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Thoralf Herrmann
Scientist Neurophysics
T +49 (0)7121 51530-852
F +49 (0)7121 51530-62

Areas of activity

Electrical stimulation and derivation of nerve cells in tissue sections and cell culture. Analysis of activity patterns of neuronal networks in vitro. Characterization of microelectrode arrays. Development, support and application of MEA technology.

Stages of career

Since 1999    Scientific assistant at the NMI Reutlingen

1988-1998     Study of Physics at the University of Tübingen, Diploma Thesis at the NMI Reutlingen

Dr. Gerhard Heusel
Scientist Microsystems and nanotechnology
T +49 (0)7121 51530-22
F +49 (0)7121 51530-62

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Christoph Hofer
Scientist Advanced Materials
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Dr. Ellena Hönig
Scientist Regenerative biomaterials
T +49 (0)7121 51530-868
F +49 (0)7121 51530-62
Elvina Houas
Engineer Interface analytics in production processes
T +49 (0)7121 51530-53
F +49 (0)7121 51530-62
Joana Hummel
Scientist Adhesive bonding and test engineering
T +49 (0)7121 51530-884
F +49 (0)7121 51530-62
Dragana Ivančić
Assistance/HR
T +49 (0)7121 51530-11
Francesca Izzi
PhD student Neuromicrophysiological systems
T +49 (0)7121 51530-829
F +49 (0)7121 51530-62
Meike Jakobi
PhD student Biochemistry
T +49 (0)7121 51530-412
F +49 (0)7121 51530-62
Pauline Jeckel
PhD student Molecular neurobiology
T +49 (0)7121 51530-867
F +49 (0)7121 51530-62

Doktorandin Sprecherin

Laura Jentsch
PhD student Neuromicrophysiological systems
T +49 (0)7121 51530-829
F +49 (0)7121 51530-62
Dr. Peter D. Jones
Group Leader Microsystems and nanotechnology
T +49 (0)7121 51530-800
F +49 (0)7121 51530-62

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Dr. Thomas Joos
Deputy Director
T +49 (0)7121 51530-844
F +49 (0)7121 51530-16
Qualifications and history:

Since 2013: Deputy Managing Director, NMI

2008 - 2014 Director Strategic Alliances, EDI GmbH, Reutlingen (part time)
 
2000 - 2017 Head of Biochemistry Department, NMI
 
1998 - 2000 Research Assistant, NMI
 
1994 – 1998: Postdoctoral research, Dept. of Cell Biology, Max Planck Institute for Developmental Biology, Tübingen
 
1994: Ph.D. degree (Dr. rer. nat), Dept. of Cell Biology, Max Planck Institute for Developmental Biology, Tübingen (under Prof. P. Hausen; Topic: "Integrin-α5 during early embroygenesis of Xenopus laevis"
 
04–08 1988: Molecular biology practical, Biochemistry Dept., the Brandeis University“(under Prof. Andrew Szent-Györgyi), Waltham, Massachusetts, USA
 
1984 – 1990: Study of Biochemistry, University of Tübingen

Dr. Joos is a member of the editorial board of "Drug Discovery Today", "Proteomics" and "Expert Review of Proteomics".
He is a member of the Scientific Advisory Board of the Plasma Proteomics Institute in Washington, DC, USA and a member of the Scientific Advisory Board of Myriad RBM Inc. in Austin, Texas, USA.

Dr. Joos is the author of >100 scientific papers. He is recognized worldwide as an expert and opinion leader in the technology field of biomarkers and their clinical applications and basic research.

Dr. Joos is co-founder of SIGNATOPE GmbH, Reutlingen. SIGNATOPE develops innovative protein tests with which biomarkers for organ damage and drug interactions can be detected in all pharma-relevant species.

 
Dr. Philipp Kaiser
Scientist Cellular screening models
T +49 (0)7121 51530-411
F +49 (0)7121 51530-62

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Anna-Lena Keller
PhD Student Tumor Biology
T +49 (0)7121 51530-868
F +49 (0)7121 51530-62
Lisa Kollmannthaler
Scientist Microsystems and nanotechnology
T +49 (0)7121 51530-607
F +49 (0)7121 51530-62
Dr. Fabian Körte
Scientist Biofunctionalized surfaces
T +49 (0)7121 51530-845
F +49 (0)7121 51530-62
Prof. Dr. Rumen Krastev
Scientist Biofunctionalized surfaces
T +49 (0)7121 51530-873
F +49 (0)7121 51530-16

Areas of activity

polymer / polyelectrolyte thin films, nano technology, biomaterials, solid / liquid surfaces, foams

Stages of career

2011 - 2018 Head of Bioorganic Chemistry and Bioanalytics Division

2008 - 2018 Head of Biomaterials working group at the NMI

2005 - 2008 Research Associate at the Max Planck Institute for Colloids and Interfaces (MPI KG), Group Leader - Soft Thin Films

2002 - 2005 Scientific research (neutron reflectometry) Hahn-Meitner Institut, Berlin

1996 - 2002 PostDoc / Scientific employee at MPI KG, Dept. Interfaces, Golm/Potsdam

1996 Doctorate at the University of Sofia

1993-1998 Research stay at Bristol University, GB

1986 - 1995 Junior Professor of Physical Chemistry and Surface Chemistry (University of Sofia, Bulgaria)

1985 Diploma, Chemistry - Inorganic and Physical Chemistry

Dr. Udo Kraushaar
Group Leader Electrophysiology
T +49 (0)7121 51530-851
F +49 (0)7121 51530-16

Research interests

Function and dynamics of ion channels at the cellular level and in organo-near systems (acute and organotypic tissue preparations, cell clusters). Special emphasis is put on the clarification of neurobiological and cardiorelevant questions. 

Curriculum vitae

Since 2007 deputy group leader electrophysiology

2004-2007 Research associate at Saarland University Hospital, Molecular Cell Biology Prof. Lipp

2002-2004 Postdoctoral Associate Yale University, USA, Neurobiology Prof. McCormick

2000-2002 Scientific assistant at the University of Freiburg, Physiology I  Prof. Jonas

1995-2000 PhD on synaptic transmission in the hippocampus

1995 Diploma in Biology University of Kaiserslautern, Zoology Prof. Deitmer

Robin Kretz
PhD student Bioanalytics
T +49 (0)7121 51530-890
F +49 (0)7121 51530-62
Dr. Martin Kriebel
Scientist Molecular neurobiology
T +49 (0)7121 51530-810
F +49 (0)7121 51530-62

Areas of activity

- Light microscopic methods (confocal, wide field microscopy; high content analysis)
- Neuronal model systems in vitro and in vivo
- Drug testing in neuronal culture systems
- Molecular genetic knockdown methods (shRNA, miRNA, siRNA) in vitro and in vivo
- Individualized lentiviral transduction systems
- Immunocyto-, histochemistry; 3D-reconstruction of biological sample material
- Non-marking detection method

Stages of career

Since 2008 project manager, Department of Molecular Neurobiology, NMI

2005 - 2008 Research associate at the Department of Molecular Biology, NMI

2005 Postdoctoral research fellow, Institute for Developmental Biochemistry, Georg-August-Universität Göttingen 

2005 PhD in Developmental Biology at the Georg-August-University Göttingen on morphogenetic factors of head development in vertebrates

1996 - 2001 Study of Biology at the Georg-August-Universität Göttingen

1995 - 1996 Study of Social Sciences with focus on Economics, Psychology at the Justus-Liebig-University Gießen, Germany

Meng-Jung Lee
PhD student Neurophysics
T +49 (0)7121 51530-843
F +49 (0)7121 51530-62

--

Regina Lipp
Administration
T +49 (0)7121 51530-213
F +49 (0)7121 51530-16
Dr. Tarek Lutz
Group Leader Interfaces and Nanoanalytics
T +49 (0)7121 51530-900
F +49 (0)7121 51530-62

Stages of career

since 2012 NMI, Project leader Nano analytics, Head of NMI Nano analytic laboratory, Physicist
2007-2012 Senior experimental Officer, Marie-Curie senior research fellow (EU/FP7), CRANN/Trinity College, Dublin, Ireland
2005-2007 Staff engineer, Physicis, Qimonda, Dresden, Germany
2004-2005  Senior researcher, Physicist, Infineon, Cooperate Research (CPR) Munich, Germany
1999-2004  Senior engineer, Physicist, Infineon, Mask House, Munich, Germany
1997-1999  Physicist; Masterstudent, NMI Reutlingen,Germany
1997-1998  Kleindiek Nanotechnik, Reutlingen, Germany

Education:
2007-2012 Trinity College Dublin, Dublin, Ireland
- Contact interface studies of metal and carbon electrodes to germanium nanowires, carbon nanotubes and thin carbon films in associated devices”
- PHD Thesis conducted at the School of Physics at the Trinity College in Dublin (Ireland)
1997-1998 University of Tübingen, Tuebingen, Germany
- “Target preparation strategies using focused Ion beam technique (FIB) to investigate internal interfaces in Transmission Electron Microscopy”
-  Master Thesis conducted at the Bosch Research Center and the Natural and Medical Science Institute (NMI)
1998-1997 University of Tübingen, Tuebingen, Germany

Publications outside the NMI

Contact resistivity and suppression of Fermi level pinning in side-contacted germanium nanowires; MM Koleśnik-Gray, T Lutz, G Collins, S Biswas, JD Holmes, V Krstić; Applied Physics Letters 103 (15), 153101    9    2013

Fabrication of a sub-10 nm silicon nanowire based ethanol sensor using block copolymer lithography;
S Rasappa, D Borah, CC Faulkner, T Lutz, MT Shaw, JD Holmes, ...; Nanotechnology 24 (6), 065503    22    2013

Contact Interface Studies of Metal and Carbon Electrodes to Germanium Nanowires, Carbon Nanotubes and Thin Carbon Films in Associated Devices; T Lutz; Trinity College Dublin        2013

Free-Standing, Single-Crystal Cu3Si Nanowires; SJ Jung, T Lutz, AP Bell, EK McCarthy, JJ Boland; Crystal Growth & Design 12 (6), 3076-3081    22    2012

Large-scale parallel arrays of silicon nanowires via block copolymer directed self-assembly; RA Farrell, NT Kinahan, S Hansel, KO Stuen, N Petkov, MT Shaw, ...; Nanoscale 4 (10), 3228-3236    51    2012

Resolving In Situ Specific‐Contact, Current‐Crowding, and Channel Resistivity in Nanowire Devices: A Case Study with Silver Nanowires; MM Koleśnik, S Hansel, T Lutz, N Kinahan, M Boese, V Krstić; Small 7 (20), 2873-2877    11    2011

Anisotropic etching induced by surface energy driven agglomeration; S Jung Jung, T Lutz, JJ Boland; Journal of Vacuum Science & Technology A: Vacuum, Surfaces, and Films 29 (5 …    7    2011

Surface energy driven agglomeration and growth of single crystal metal wires; SJ Jung, T Lutz, M Boese, JD Holmes, JJ Boland; letters 11 (3), 1294-1299    13    2011

Nanoscale mapping of electrical resistivity and connectivity in graphene strips and networks; PN Nirmalraj, T Lutz, S Kumar, GS Duesberg, JJ Boland; Nano letters 11 (1), 16-22    91    2010

Transparent ultrathin conducting carbon films; M Schreiber, T Lutz, GP Keeley, S Kumar, M Boese, S Krishnamurthy, ...; Applied Surface Science 256 (21), 6186-6190    30    2010

An investigation of the electrical properties of pyrolytic carbon in reduced dimensions: Vias and wires; AP Graham, G Schindler, GS Duesberg, T Lutz, W Weber; Journal of Applied Physics 107 (11), 114316    22    2010

Transparent ultrathin conducting carbon films; M BOESE, GS DUESBERG, T LUTZ, S KUMAR; Applied Surface Science;        2010

Gas phase controlled deposition of high quality large-area graphene films; S Kumar, N McEvoy, T Lutz, GP Keeley, V Nicolosi, CP Murray, WJ Blau, ...; Chemical communications 46 (9), 1422-1424    44    2010

CVD Growth of Nanocarbons for Device Applications; N Mc Evoy, S Kumar, T Lutz, G Keeley, W Blau, G Duesberg; Meeting Abstracts, 2213-2213        2009

Low temperature graphene growth; S Kumar, N McEvoy, T Lutz, G Keeley, N Whiteside, W Blau, GS Duesberg; ECS Transactions 19 (5), 175-181    7    2009

One-and Two-Dimensional Carbon Nanostructures for applications in Microelectronic Devices and Electrochemical Sensors; G Keeley, T Lutz, N McEvoy, S Kumar, M Schreiber, N Whiteside, ...; Meeting Abstracts, 1313-1313        2009

Fabrication of all-Carbon Nanodevices; T Lutz, S Krishnamurthy, M Schreiber, G Keeley, GS Duesberg; Meeting Abstracts, 2135-2135        2008

Process for producing a mask; T Lutz, J Schneider; US Patent 7,410,732        2008

Integration of EBDW of one entire metal layer as substitution for optical lithography in 220 nm node microcontrollers; J Kretz, H Roeper, C Arndt, T Bischoff, KH Choi, G Goldbeck, M Gunia, ...; Microelectronic Engineering 85 (5-6), 792-795    9    2008

Determination of best focus and optimum dose for variable shaped e-beam systems by applying the isofocal dose method; K Keil, KH Choi, C Hohle, J Kretz, T Lutz, L Bettin, M Boettcher, ...; Microelectronic Engineering 85 (5-6), 778-781    6    2008

Evaluation of hybrid lithography and mix and match scenarios for electron beam direct write applications; C Hohle, C Arndt, KH Choi, J Kretz, T Lutz, F Thrum, K Keil; Journal of Vacuum Science & Technology B: Microelectronics and Nanometer …    8    2007

Apparatus and method for determining physical properties of a mask blank; T Lutz, M Menath; US Patent 7,289,231        2007

CD control of direct versus complementary exposure for shaped beam writers and its correlation to the local registration error; F Thrum, KH Choi, T Lutz, C Hohle, C Arndt, M Tesauro, MT Bootsmann, ...; Microelectronic engineering 84 (5-8), 1033-1036    3    2007

Fabrication of a nano-scale NAND memory array based on a SONOS Fin-FET cell using e-beam lithography and hydrogen-silsesquioxane resist; T Lutz, M Specht, L Risch, C Friederich, L Dreeskornfeld, J Kretz, ...; Microelectronic engineering 84 (5-8), 1578-1580    7    2007

Defect inspection of positive and negative sub-60nm resist pattern printed with variable shaped E-Beam direct write lithography; C Arndt, C Hohle, J Kretz, T Lutz, M Richter, K Keil, M Lapidot, D Zemach, ...; Emerging Lithographic Technologies XI 6517, 651711        2007

Data preparation for EBDW; F Thrum, J Kretz, T Lutz, K Keil, C Arndt, KH Choi, U Baetz, N Belic, ...; Mask and Lithography Conference (EMLC), 2007 23rd European, 1-8    3    2007

Multi-level p+ tri-gate SONOS NAND string arrays; C Friederich, M Specht, T Lutz, F Hofmann, L Dreeskornfeld, W Weber, ...; Electron Devices Meeting, 2006. IEDM'06. International, 1-4    17    2006

Method for detecting and compensating for positional displacements in photolithographic mask units and apparatus for carrying out the method; J Schneider, T Lutz; US Patent 7,087,910    5    2006

Comparison of trimming techniques for sub-lithographic silicon structures; L Dreeskornfeld, AP Graham, J Hartwich, J Kretz, E Landgraf, T Lutz, ...; Japanese journal of applied physics 45 (6S), 5552    5    2006

Influence of crystal orientation and body doping on trigate transistor performance; E Landgraf, W Rösner, M Städele, L Dreeskornfeld, J Hartwich, ...; Solid-state electronics 50 (1), 38-43    46    2006

Comparison of trimming techniques for sub-lithographic silicon structures; L Dreeskornfeld, AP Graham, J Hartwich, E Landgraf, T Lutz, W Rosner, ...; Microprocesses and Nanotechnology Conference, 2005 International, 152-153        2005

Method for compensating for scatter/reflection effects in particle beam lithography; C Ebi, F Erber, T Franke, F Gans, T Lutz, G Ruhl, B Schönherr; US Patent 6,953,644    1    2005

Planar double gate transistors with asymmetric independent gates; G Ilicali, W Weber, W Rosner, L Dreeskornfeld, J Hartwich, J Kretz, T Lutz, ...; SOI Conference, 2005. Proceedings. 2005 IEEE International, 126-127    10    2005

Comparative study of calixarene and HSQ resist systems for the fabrication of sub-20 nm MOSFET device demonstrators; J Kretz, L Dreeskornfeld, G Ilicali, T Lutz, W Weber; Microelectronic engineering 78, 479-483    19    2005

Investigation of Low Damage Mask Repair by Combination of Electron Beam and Scanning Force Technology; C Burkhardt, S Bauerdick, V Bucher, W Barth, A Ehrmann, T Lutz, J Rau, ...; Micro and Nano Engineering    1    2002

FOx-12 flowable oxide ; L Dreeskornfeld, AP Graham, J Hartwich, J Kretz, E Landgraf, T Lutz, ...;

Proc. Micro-and Nano Engineering 2005 Proc. Micro-and Nano Engineering 2005, 2005; L Dreeskornfeld, AP Graham, J Hartwich, J Kretz, E Landgraf, T Lutz, ...

IEDM Tech. Dig., 2004 IEDM Tech. Dig., 2004, 2004; L Dreeskornfeld, AP Graham, J Hartwich, J Kretz, E Landgraf, T Lutz, ...

Sandra Maier
Scientist Bioanalytics
T +49 (0)7121 51530-817
F +49 (0)7121 51530-62
Elke Mammel-Haisch
Administration
T +49 (0)7121 51530-419
F +49 (0)7121 51530-16
Dr. Dagmar Martin
Group Leader Interface Analytics in Production Processes
T +49 (0)7121 51530-863
F +49 (0)7121 51530-62

Research interests

  • cleaning validation
  • corrosion investigations
  • process analytics

Curriculum vitae

since October 2012 Project Manager Medical Technology at the NMI Reutlingen

2007 - 2012 Product Manager at ancosys GmbH

2004 - 2007 Technical Editor at ancosys GmbH

2002 - 2004 Technical editor with focus on multimedia at Tanner Documents in Reutlingen, Germany

1999 - 2002 Programming of multimedia lecture contents as scientific employee at the University of Tübingen

1995 - 1999 Parental leave

1992 - 1995 PhD in Physical Chemistry at the University of Tübingen

1984 - 1991 Study of Chemistry at the University of Tübingen

Dr. Matthew McDonald
Scientist Biomedical Micro and Nano Engineering
T +49 (0)7121 51530-217
Prof. Dr. Jannik C. Meyer
Group Leader Advanced materials
T +49 (0)7121 51530-924
Beatriz Molina Martinez
PhD student Neuromicrophysiological systems
T +49 (0)7121 51530-829
F +49 (0)7121 51530-62
Ashutosh Mukherjee
PhD student Applied materials science and electron microscopy
T +49 (0)7121 51530-909
F +49 (0)7121 51530-62
Katharina Neufeld
Scientist BioMEMS and sensors
T +49 (0)7121 51530-832
Anita Niedworok
Scientist Neuromicrophysiological systems
T +49 (0)7121 51530-829
Dr. Wilfried Nisch
Senior scientist Applied materials science and electron microscopy
T +49 (0)7121 51530-40
F +49 (0)7121 51530-62

Areas of activity

  •     Micro- and Nanotechnology
  •     thin film technology
  •     Electron and ion beam technology
  •     Electron microscopy and microanalysis
  •     Vacuum and cryo technology

 

Matthias Nützel
Head of financal accounting
T +49 (0)7121 51530-14
F +49 (0)7121 51530-16
Yana Parfyonova
PhD student Cellular screening models
T +49 (0)7121 51530-411
F +49 (0)7121 51530-16
Jessica Pfannstiel
Technical assistant Regenerative biomaterials
T +49 (0)7121 51530-393
F +49 (0)7121 51530-62
Bettina Pfister
Administration
T +49 (0)7121 51530-834
F +49 (0)7121 51530-16
Annelie Pohle
Technical assistant Biochemistry
T +49 (0)7121 51530-472
F +49 (0)7121 51530-62
Dr. Oliver Pötz
Scientist Protein Analytics

--

Claudia Prax
Administration
T +49 (0)7121 51530-834
F +49 (0)7121 51530-16
Dr. Stefan Raible
Deputy Director
T +49 (0)7121 51530-15
F +49 (0)7121 51530-16
Miriam Reh
PhD student Neurophysics
T +49 (0)7121 51530-892
F +49 (0)7121 51530-62
Justine Rehbronn
Scientist Applied materials science and electron microscopy
T +49 (0)7121 51530-907
F +49 (0)7121 51530-16
Benedikt Reichel
Engineer Interfaces and nanoanalytics
T +49 (0)7121 51530-823
Gabriele Reicherter
Receptionist
T +49 (0)7121 51530-0
F +49 (0)7121 51530-62
Karl Reuter
Technician
T +49 (0)7121 51530-522
F +49 (0)7121 51530-16
Frank Roloff
IT
T +49 (0)7121 51530-215
F +49 (0)7121 51530-62
Katja Rösslein
Head of Administration
T +49 (0)7121 51530-70
F +49 (0)7121 51530-16

Curriculum vitae

Head of Administration of the NMI
since October 2018

Head of Administration of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart
Nov. 2015-Sep. 2018

Head of Human Resources, Deputy Head of Administration
Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart
Apr. 2009-Oct. 2015

Human Resources, Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart
Sep. 1999-March 2009

Prof. Dr. Ulrich Rothbauer
Head of Dept. Pharma and Biotech, Joint Professorship
T +49 (0)7121 51530-415
F +49 (0)7121 51530-16

Curriculum vitae

Since 2011
Professor of Pharmaceutical Biotechnology at the University of Tübingen (Joint Professor with NMI)

2008 - 2011
Managing Director of the biotechnology company ChromoTek GmbH (Martinsried, Germany)

2008 - 2010
Junior Research Group Leader, Institute of Biology, LMU Munich

2006 - 2007
Project Leader "Chromobodies", Project Leader "Chromobodies", Institute of Biology, LMU Munich, Germany

2004 - 2005
Post-Doc, Institute of Biology, LMU Munich under Prof. Dr. Heinrich Leonhardt

2003 - 2004
Post-doctoral fellow, Institute for Academic Diabetes Research Hospital, Munich under PD Dr. Mathias Baucher

1999 - 2003
Dissertation (Dr. rer. nat.; PhD) at the Institute of Physical Chemistry, LMU Munich under Prof. Dr. Dr. Walter Neuwert: "Functional characterization of a mitochondrial mediate disease: The role of DDP1 and Tim13 for mitochondrial biogenesis".

1998
Diploma in Biology under Prof. Dr. Svante Pääbo: In vitro processing of overlapping tRNA transcripts in human mitochondria

1992 - 1998
Study of Biology at the Ludwig-Maximilians University of Munich

 

Tina Rudolf
Engineer Interface analytics in production processes
T +49 (0)7121 51530-475
F +49 (0)7121 51530-62

Research interests

  • electron microscopy
  • FIB/SEM Crossbeam
  • nanohardness
  • preparation methods


Stages of career

Since 2008 Engineer in the group Interfacial and Microstructure Analysis

2002-2007 Study of Geosciences with specialization in Mineralogy

Alexander Rudt
PhD student Biofunctionalized surfaces
T +49 (0)7121 51530-
Felix Ruoff
PhD student Assay development
T +49 (0)7121 51530-818
Eugenia Salzmann
PhD student Bioanalytics
T +49 (0)7121 51530-890
F +49 (0)7121 51530-62
Prof. Dr. Katja Schenke-Layland
Director
T +49 (0)7121 51530-10
F +49 (0)7121 51530-16
Dr. Christian Schmees
Group Leader Tumor biology
T +49 (0)7121 51530-881
F +49 (0)7121 51530-16

Research interests

  • Patient-derived ex-vivo tumor models and their application in preclinical compound efficacy testing
  • Tumor-Immune cell interactions with a focus on T lymphocytes and macrophages
  • Optogenetic modulation of cell-cell communication and cell signalling
  • CRISPR-based genome editing for target validation and cell engineering

 

Academic career

since 2014
Head of Tumor Biology, NMI

2011 - 2014
Senior Scientist, Tumor Biology Group, NMI

2010 - 2011
Senior Scientist at the Department of Systemic Cell Biology (Prof. Philippe Bastiaens), Max-Planck-Institute of Molecular Physiology, Dortmund, Germany

2006 – 2010
Research Fellow at the Ludwig Institute for Cancer Research (LICR; Prof. Carl-Henrik Heldin) Uppsala, Sweden (Scholarships from LICR and DFG (German Research Foundation) “Investigation of Differences in Regulation of intracellular trafficking of PDGF α- and β-receptors”

2002 – 2006
PhD in Tumor Immunology at the Department of Medicine II, Technical University of Munich, Germany

1996 – 2002
Biochemistry studies at the University of Halle-Wittenberg and University of Tübingen, Germany;
Degree: Diploma

Publications

Schmees C, Villaseñor R, Zheng W, Ma H, Zerial M, Heldin CH, Hellberg C. Macropinocytosis of the PDGF β-receptor promotes fibroblast transformation by H-RasG12V. Mol Biol Cell. 2012 Jul;23(13):2571-82.

Hellberg C, Schmees C, Karlsson S, Ahgren A, Heldin CH. Activation of protein kinase C alpha is necessary for sorting the PDGF beta-receptor to Rab4a-dependent recycling. Mol Biol Cell. 2009 Jun;20(12):2856-63.

Schmees C, Gerhard M, Treptau T, Voland P, Schwendy S, Rad R, Prinz C. VacA-associated inhibition of T-cell function: reviewed and reconsidered. Helicobacter. 2006 Jun;11(3):144-6.

Schmees C, Prinz C, Treptau T, Rad R, Hengst L, Voland P, Bauer S, Brenner L, Schmid RM, Gerhard M. Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase. Gastroenterology. 2007 May;132(5):1820-33.

Gerhard M, Schmees C, Voland P, Endres N, Sander M, Reindl W, Rad R, Oelsner M, Decker T, Mempel M, Hengst L, Prinz C. A secreted low-molecular-weight protein from Helicobacter pylori induces cell-cycle arrest of T cells. Gastroenterology. 2005 May;128(5):1327-39.

Felix Schmidt
PhD student Biochemistry
T +49 (0)7121 51530-890
F +49 (0)7121 51530-62

--

Christine Schmitt
Administration
T +49 (0)7121 51530-38
F +49 (0)7121 51530-16
Dr. Nicole Schneiderhan-Marra
Group Leader Biochemistry
T +49 (0)7121 51530-815
F +49 (0)7121 51530-16

Research interests   

  • Development and application of miniaturized multiplexed immunoassays in proteome research for pharmaceutical and clinical applications
  • Identification of biomarkers e.g. early detection of drugs Indicated organ damage or use for classification of tumors in personalized medicine

Curriculum vitae

since 01/2018  Head of Biochemie

06/2007 – 12/2017 Deputy Head of Department Biochemistry

05/2005 Project manager and laboratory manager at the NMI Reutlingen

2003-2005 Scientific employee at the University of Ulm, University Women's Hospital, Endocrinological and Oncological Laboratory, working group Prof. Helmut Deißler

2002 External PhD thesis (Dr. rer. nat) at the University of Tübingen, supervised by Prof. Bernhard Brüne (Medical Clinic IV, Nephrological Research Laboratories, University of Erlangen) and Prof. Dieter Mecke (University of Tübingen), Title: Molecular Mechanism of Nitric Oxide Mediated Accumulation of Tumor Suppressor p53

2011 Internship at "MD Anderson" in the group of Assistant Professor Yanping Zhang, Houston, Texas, USA

1992 - 1998 Study of Biochemistry at the Eberhard-Karls-Universität Tübingen

 

Monika Schrenk
Scientist Biochemistry
T +49 (0)7121 51530-860
F +49 (0)7121 51530-62
Ulrike Schrof
Administration
T +49 (0)7121 51530-19
F +49 (0)7121 51530-16
Dr. Birgit Schröppel
Scientist Applied materials science and electron microscopy
T +49 (0)7121 51530-822
F +49 (0)7121 51530-62

Areas of interest   

  • FIB/SEM Crossbeam
  • cryomicroscopy
  • preparation methods
  • Analytics of biological-technical interfaces
  • electron microscopy

Stages of career

Since 2009 research associate in the Microsystems and Nanotechnology Group at the NMI

2011 PhD in Applied Physics on the development of an ion optical transfer system for a mass spectrometer

2004-2009 Research Assistant at the Institute of Applied Physics, Working Group Electron and Ion Optics

1997-2004 Study of physics at the Eberhard-Karls University Tübingen

 

 

Philipp Schühle
Scientist Interfaces and nanoanalytics
T +49 (0)7121 51530-51
F +49 (0)7121 51530-62
Thomas Schweikert
Head of Administration
T +49 (0)7121 51530-885
F +49 (0)7121 51530-16
Ulrike Schwenkler
Administration
T +49 (0)7121 51530-418
F +49 (0)7121 51530-16
Sören Segan
PhD student Cellular screening models
T +49 (0)7121 51530-411
F +49 (0)7121 51530-62
Dr. Christopher Shipp
Group Leader Interface immunology
T +49 (0)7121 51530-809
F +49 (0)7121 51530-62

--

Kathrin Stadelmann
PhD student Biomaterials engineering
T +49 (0)7121 51530-414
F +49 (0)7121 51530-62
Helen Steins
PhD student Micromedical and surface engineering
T +49 (0)7121 51530-217
F +49 (0)7121 51530-62
Dr. Martin Stelzle
Group Leader BioMEMS and sensors
T +49 (0)7121 51530-75
F +49 (0)7121 51530-62

since Jan 2000   Head of BioMEMS & Sensors group

1996 - 2000  Senior Scientist, NMI, Dept. Applied Physics

1995 - 1996   Postdoc, Max-Planck Institute for Colloid and Interface Sciences, Berlin

1992-1994   Postdoc, IBM Almaden Research Center, San Jose, USA,
Polymer Science & Technology Department

1992   Ph.D. thesis, Technical University of Munich, Biophysics Institute, Prof. E. Sackmann;

1982-1988   Physics study at the University of Erlangen and the Technical University of Munich

Claudia Stippich
Technical assistant Biofunctionalized surfaces
T +49 (0)7121 51530-27
F +49 (0)7121 51530-62
Ricarda Stock
PhD student Molecular neurobiology
T +49 (0)7121 51530-867
F +49 (0)7121 51530-62
Angelika Stumpf
Technical assistant Microsystems and nanotechnology
T +49 (0)7121 51530-878
F +49 (0)7121 51530-62
Dr. Markus Templin
Group Leader Assay Development
T +49 (0)7121 51530-828
F +49 (0)7121 51530-16

Forschungsgebiete 

  • Cellular signalling pathways
  • tumor biology
  • Biomarker identification and validation
  • assay development
  • miniaturized assay systems

Stages of career

since 2003  group leader assay development

2000 - today  NMI

1996 - 2000  Research associate, Max Planck Institute for Developmental Biology, Tübingen 

1994 - 1995  Postdoc, ICMB, University of Edinburgh, Scotland, UK

Stefan Thiele
Scientist BioMEMS and sensors
T +49 (0)7121 51530-841
Katja Thurig
Technical assistant Molecular neurobiology
T +49 (0)7121 51530-393
F +49 (0)7121 51530-62
Dr. Björn Tränkle
Scientist Cellular screening models
T +49 (0)7121 51530-411
F +49 (0)7121 51530-62

--

Matthijs van der Moolen
PhD Student Neuromicrophysiological Systems
T +49 (0)7121 51530-829
Prof. Dr. Hansjürgen Volkmer
Head of Dept. Pharma and Biotech, Head of Neurobiology
T +49 (0)7121 51530-44
F +49 (0)7121 51530-16

Research interests

  • Molecular mechanisms of neuronal plasticity

Curriculum vitae

Since 1998 Head of the Molecular Biology Department

1994 - 1998 Postdoc at the Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany

1989 - 1994 Postdoctoral research fellow at the Center for Molecular Neurobiology, Hamburg

1989 PhD in Genetics, University of Tübingen, Germany

1979 - 1984 Study of Biology, University of Tübingen

 

Dr.-Ing. René von Metzen
Deputy Head of Department Biomedicine and Material Sciences
T +49 (0)7121 51530-609
F +49 (0)7121 51530-62

Research interests

  • microimplants
  • microsystems engineering
  • encapsulation technology
  • coating technologies

Curriculum vitae

since 2019 - Deputy Head of Department Biomedicine and Material Sciences

2014 - today Group Leader Biomedical Micro and Nano Engineering

2013 - 2014 Staff member at the NMI, Micromedicine and Surface Technology Working Group 

2005 - 2013 Research associate at the Institute of Microsystems Technology (IMTEK) at the University of Freiburg, Chair of Biomedical Microtechnology (Prof. Stieglitz)

2012 PhD, title of dissertation: 'Parylene C as a Substrate Material for Micro Implants'.

1997 - 2004 Studies of Electrical Engineering (Technical University Berlin)

 

Larissa Walter
PhD student Bioanalytics
T +49 (0)7121 51530-410
F +49 (0)7121 51530-62
Bernadette Walter
PhD Student Interface Immunology
T +49 (0)7121 51530-0
F +49 (0)7121 50530-62
Clementine Warres
Engineer Interfaces and nanoanalytics
T +49 (0)7121 51530-50
F +49 (0)7121 51530-62
Sonja Weckerle
Administration
T +49 (0)7121 51530-17
F +49 (0)7121 51530-16
Dr. Frank Weise
Group Leader Molecular Biology and Neurobiology
T +49 (0)7121 51530-56
F +49 (0)7121 51530-62

Research interests

Development of improved cell culture models and methods for gene transfer

Fields of activity

We focus on the analysis of cellular responses to gene expression in order to validate target genes for the pharmaceutical industry. Furthermore, we aim at developing improved cell culture models (co-culture, inflammatory response to exposure to hazardous substances), which, due to their more physiological nature, allow higher predictivity.

Curriculum vitae

since 2009 Group leader of Target Expressions Systems
2002-2009 Head of laboratory in the Dept. of Molecular Biology
1998-2002 Post-doctoral fellow at the Max Planck Institute of Biology, Tübingen
1997 Doctoral degree at the Free University of Berlin (bacteriophage DNA replication)
1994-1996 Doctoral fellow at the National Centre of Biotechnology, Madrid, Spain
1987-1993 Student of biochemistry at the Free University of Berlin

 

Simon Werner
Engineer BioMEMS and sensors
T +49 (0)7121 51530-899
F +49 (0)7121 51530-62

Arbeitsgebiete

  • System integration of electronics and microfluidics for biological applications in 
  • Lab on a Chip Systems, Microfluidics - Design,
  • Peripheral systems for dielectrophoresis and fluidic control,
  • rapid prototyping: 3D CAD (SolidWorks®), CAM/CAE, micro milling, AVT
  • opt. Sensors/ Measurement technology

Stages of career

since 2009  Part-time Master's degree in Electrical Engineering/ Information Technology, Open University in Hagen, Germany

since 2007  Scientific employee/engineer at the AG BioMEMS Sensorik

2003 - 2007  Studied Mechatronics at the FH Reutlingen

2001 - 2006  Scintec AG, Atmospheric Measurement Technology

 

Dr. Jenny Wickham
Scientist Neurophysics
T +49 (0)7121 51530-843
F +49 (0)7121 51530-62
Dr. Xin Xiong
Group Leader Biofunctionalized Surfaces
T +49 (0)7121 51530-413
F +49 (0)7121 51530-62

Research interests   

  • Biomaterials for medical and biotechnological approaches, in particular collagen-based biomaterials for regenerative medicine and enzyme immobilization
  • Functional characterization using physical-chemical and biological methods
  • Practical experience in molecular biology with cloning, expression in bacteria, fungi and mammalian cells, PCR, RT-PCR.
  • Physical methods: AFM, Raman spectroscopy, DSC, IR.

Curriculum vitae

Since 2017 group leader biofunctionalized surfaces

Since Oct. 2014 Deputy Group Leader, Group Biomaterials, NMI; Focus: Biotechnology and Surface Characterization:

Since Sept. 2012 Project leader Biomaterials Group

Since April 2011 Scientist Biomaterials Group at the NMI

2009 - 2011 Scientist at the Institute for Experimental Internal Medicine, University Hospital Magdeburg, focus NF-kB signaling

2008 - 2009 Scientist at the Institute of Technical Biochemistry (Group Biocatalysis), University of Stuttgart, focus on mutagenesis and enzyme expression.

2005 - 2008 PhD at the Fraunhofer IGB & Biological Institute of the University of Stuttgart: New insights into Structure and Function of Type I Collagen

2004 - 2004 Diploma thesis at Fraunhofer IGB: Functional characterization of Tsa1p in Candida albicans

2002 - 2004 Studied technical biology at the University of Stuttgart

1996 - 2000 Study of Bioprocess Engineering at Huaqiao University, China


Prices. 10.2005 First Hugo violinist Prize

10.2005 First Hugo Violinist Prize

01.2005-07.2008 Scholarship of Peter and Traudl Engelhorn Foundation

10.2008 BP-Young Scientists & Students Award at the 13th International Biotechnology Symposium and Exhibition

 

Dr. Simge Yüz
Scientist Tumour biology
T +49 (0)7121 51530-867
F +49 (0)7121 51530-62

Areas of activity:
Patient-derived ex-vivo 3D tumor models and their preclinical application in compound efficacy testing
Cell interactions between patient-derived tumor cells and autologous T lymphocytes
Modulation of cell-cell communication and signaling with optogenetics

Stages of career:
since 2018   Postdoctoral researcher, NMI

2014-2018   PhD in Biosciences, MPI for Medical Research/University of Heidelberg, Heidelberg
Mentor: Prof. Dr. Joachim P. Spatz
Title: Re-programming cell interactions with light-dependent heterodimers

2012-2014   M. Sc. in Biology, LMU, Munich/Germany

2007-2012  B.Sc. in Biology, METU, Ankara/Turkey

2006-2011   B.Sc. in Chemistry, METU, Ankara/Turkey

Publications:
Yüz SG, Ricken J, Wegner SW. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Advanced Science. 2018 Aug; 5(8): 1800446.

Yüz SG, Rasoulinejad S, Müller M, Wegner AE, Wegner SW. Blue Light Switchable Cell-Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Advanced Biosystems. 2019 Jan 18, https://doi.org/10.1002/adbi.201800310

Dr. Anne Zeck
Group Leader Bioanalytics
T +49 (0)7121 51530-811
F +49 (0)7121 51530-62

Research interests

Analytical chemistry with focus on chromatography and mass spectrometry of peptides and proteins

  • Detailed characterization of recombinant proteins and protein conjugates
  • Determination of identity / investigation of polyclonality
  • Determination of the coupling density of protein conjugates
  • High sensitivity sequence variant analysis
  • Determination of correct disulfide bridging
  • GlycosylationDetermination of N- and C-terminal modifications
  • Oxidation, deamidation, succinimide formation, glycation, etc.
  • Epitope mapping using H/D exchange and top down mass spectrometry
  • Immunoanalytical methods for the production and characterization of antibodies

Analytical Techniques

  • mass spectrometry
  • LTQ Orbitrap & LTQ-FT-ICR (ThermoScientific)
  • ESI-ToF and ESI-Q-ToF (MAXIS, Bruker)
  • MALDI-ToF-ToF
  • chromatography
  • HPLC, (Ultimate 3000, Agilent 1100, nanoAcquity)
  • UPLC, RSLC (nanoAcquity, Ultimate 3000)
  • On-line enrichment
  • immunonalytics
  • ELISA, immunoprecipitation, immunaffinity enrichment
  • Immunoanalytical detection of chromatographic separations

other protein analytical techniques

  • ion scarf chromatography
  • SDS-PAGE, Western Blot

 

Curriculum vitae

2007 - 2011 Group leader, Roche Diagnostics GmbH, Penzberg

2006 - 2007 Postdoc at Roche Diagnostics GmbH, Penzberg

2004 Postdoc at Barnett Institute of Chemical and Biological Analysis Northeastern University, Boston, USA

2001 Dr. rer. nat. in Analytical Chemistry, Technical University Munich (TUM)

1992 - 1998 Chemistry studies and Dipl. Chem. at the TU Karlsruhe and TUM

 

Dr. Günther Zeck
Group Leader Neurophysics
T +49 (0)7121 51530-807
F +49 (0)7121 51530-62

Research interests  

Neurotechnologies and applications

  • CMOS - based neurochips
            Parallel detection of neuronal activity with 16000 sensors
            Capacitive stimulation of neuronal activity with capacitor arrays
            Tissue analysis - chip coupling
  • multi-electrode arrays
            Neuronal cell cultures (rat)
            Electrical stimulation
  • retina
            Detection/analysis of extracellular activity in rabbit, rat and mouse retinas
            Detection/analysis of single cell activity and field potentials in blind retinas
            Electrical stimulation of healthy and blind retinas

Curriculum vitae

Group leader at the NMI since 2010

2006 - 2010 Senior Postdoc, Max Planck Inst. Neurobiology, Martinsried

2003 - 2005 Postdoctoral researcher at Mass. General Hospital & Harvard Medical School, Boston, USA.

1998-2002 Dr. rer. nat., Biophysics, TU Munich & Max Planck Inst. Biochemistry

1992 - 1998 Physics studies at the TU Munich

Teachings

Graduate School of Neural Information Processing, Bernstein Centre Tübingen

Student Assistants

Jasmin Buch
Student BioMEMS and Sensors
T +49 (0)7121 51530-0
F +49 (0)7121 511530-62
Marc Geißler
Student Cellular screening models
T +49 (0)7121 51530-411
F +49 (0)7121 51530-62
Paul Henzler
Master student Microsystems and nanotechnology
T +49 (0)7121 51530-874
F +49 (0)7121 514530-62
Patrick Herter
Master student Assay development
T +49 (0)7121 51530-410
F +49 (0)7121 51530-62
Anika Müller
Student Tumorbiology
T +49 (0)7121 51530-887
F +49 (0)7121 51530-62
Andreas Neusch
Master student BioMEMS and sensors
T +49 (0)7121 51530-874
Jessica Pollok
Student Cellular screening models
T +49 (0)7121 515306-0
F +49 (0)7121 51530-62
Jennifer Schieber
Student Tumorbiology
T +49 (0)7121 51530-887
F +49 (0)7121 51530-62
Julia Thierschmidt
Master student BioMEMS/Sensors
T +49 (0)7121 51530-870
F +49 (0)7121 51530-62
Oliver Walker
Student Biofunctionalized surfaces
T +49 (0)7121 51530-825
F +49 (0)7121 51530-62