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Günther Zeck
Dr. Günther Zeck
Diplom-Physiker
Neurophysik
Tel.: 07121 51530-807
Fax: 07121 51530-62

Arbeitsgebiete
Neurotechniken und Anwendungen
CMOS - basierte Neurochips
- Parallele Detektion neuronaler Aktivität mit 16000 Sensoren
- Kapazitive Stimulation neuronaler Aktivität mit Kondensatorarrays  
- Analyse der Gewebe – Chip Kopplung
Multi-Elektroden-Arrays
- Neuronale Zellkulturen (Ratte)
- Elektrische Stimulation
Retina
- Detektion/Analyse extrazellulärer Aktivität in Kaninchen-, Ratten und Mausretina
- Detektion/Analyse von Einzelzellaktivität und Feldpotentialen in blinden Retinas
- Elektrische Stimulation von gesunden und blinden Retinas

Wissenschaftlicher Werdegang mit den wichtigsten Stationen
Seit 03/10        Gruppenleiter am NMI
07/06 - 02/10  Senior Postdoc,  Max Planck Inst. Neurobiologie, Martinsried
01/03 - 12/05  Postdoc am Mass. General Hospital & Harvard Medical School, Boston, USA.
02/98 - 09/02  Dr. rer. nat.,  Biophysik, TU München &  Max Planck Inst. Biochemie
11/92 - 01/98  Physikstudium  an der TU München

Lehre
Graduate School of Neural Information Processing, Bernstein Zentrum Tübingen

Zusätzliche LIteratur
Zeck, G., Lambacher A., Fromherz, P. Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response Plos ONE in press 2011
Menzler, J., Zeck, G., Network oscillations in rod-degenerated mouse retinas J. Neurosci. 31:2280-2291 2011
Macke, J., Zeck, G.M., Bethge.,M. Receptive Fields without Spike-Triggering, Neural Information Processing Systems, 20: 529-536, 2008
Zeck, G.M, Masland R.H. Spike Train Signatures of Retinal Ganglion Cell Types. Eur. J. Neurosci., 26: 367-380, 2007
Koizumi, A., Zeck, G., Ben, Y., Masland R.H., Jakobs, T.C. Organotypic Culture of Physiologically Functional Adult Mammalian Retinas, PLoS ONE, 2, e221, 2007
Zeck, G.M, Quan, X., Masland R.H. The spatial filtering properties of local edge detectors and brisk-sustained retinal ganglion cells. Eur. J. Neurosci., 22:2016-2026, 2005.
Pouthas, G., Gentil, C., Cote, D., Zeck, G., Straub, B., Bockelmann U. Spatially resolved electronic detection of biopolymers. Phys. Rev. E 70: 031906-1, 2004.
Zeck, G., Fromherz, P. Repulsion and attraction by extracellular matrix protein in cell adhesion studied with nerve cells and lipid vesicles on silicon chips. Langmuir, 19: 1580-1585, 2003.
Zeck, G., Fromherz, P. Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip. Proc.Natl.Acad.Soc USA, 98: 10457-10462, 2001.

Publikationen

Rocha, P. R., Schlett, P., Kintzel, U., Mailander, V., Vandamme, L. K., Zeck, G., Gomes, H. L., Biscarini, F., de Leeuw, D. M. (2016).
Electrochemical noise and impedance of Au electrode/electrolyte interfaces enabling extracellular detection of glioma cell populations
Sci Rep. 2016 Oct 6;6:34843. doi: 10.1038/srep34843.

Stutzki, H., Helmhold, F., Eickenscheidt, M., Zeck, G. (2016).
Subretinal electrical stimulation reveals intact network activity in the blind mouse retina
J Neurophysiol. 2016 Oct 1;116(4):1684-1693. doi: 10.1152/jn.01095.2015. Epub 2016 Jul 13.

Leibig, C., Wachtler, T., Zeck, G. (2016).
Unsupervised neural spike sorting for high-density microelectrode arrays with convolutive independent component analysis
J Neurosci Methods. 2016 Sep 15;271:1-13. doi: 10.1016/j.jneumeth.2016.06.006. Epub 2016 Jun 15.

Samba, R., Herrmann, T., Zeck, G. (2015).
PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities
J Neural Eng. 2015 Feb;12(1):016014. doi: 10.1088/1741-2560/12/1/016014. Epub 2015 Jan 14.

Zeck, G. (2016).
Aberrant activity in degenerated retinas revealed by electrical imaging
Frontiers in Cellular Neuroscience 10.

Schultheiss, M., Schnichels, S., Hermann, T., Hurst, J., Feldkaemper, M., Arango-Gonzalez, B., Ueffing, M., Bartz-Schmidt, K. U., Zeck, G., Spitzer, M. S. (2016).
Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia
PLoS One. 2016 Feb 5;11(2):e0148616. doi: 10.1371/journal.pone.0148616. eCollection 2016.

Samba, R., Herrmann, T., Zeck, G. (2015).
PEDOT-CNT coated electrodes stimulate retinal neurons at low voltage amplitudes and low charge densities
Journal of Neural Engineering 12(1): 016014.

Menzler, J., Channappa, L., Zeck, G. (2014).
Rhythmic Ganglion Cell Activity in Bleached and Blind Adult Mouse Retinas
doi:10.1371/journal.pone.0106047

Santos-Ferreira, T., Postel, K., Stutzki, H., Kurth, T., Zeck, G., Ader, M. (2015).
Daylight vision repair by cell transplantation
Stem Cells. 2015 Jan;33(1):79-90. doi: 10.1002/stem.1824.

Eickenscheidt, M., Zeck, G. (2014).
Action potentials in retinal ganglion cells are initiated at the site of maximal curvature of the extracellular potential
J Neural Eng. 2014 Apr 24;11(3):036006.

Stutzki, H., Leibig, C., Andreadaki, A., Fischer, D., Zeck, G. (2014).
Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury
Frontiers in Cellular Neuroscience 8.

Wuchter, J., Beuter, S., Treindl, F., Herrmann, T., Zeck, G., Templin, MF., Volkmer, H. (2012)
A Comprehensive Small Interfering RNA Screen Identifies Signaling Pathways Required for Gephyrin Clustering
The Journal of Neuroscience, October 17, 32(42):14821–14834

Eickenscheidt, M., Jenkner, M., Thewes, R., Fromherz, P., Zeck, G. (2012).
Electrical stimulation of retinal neurons in epiretinal and subretinal configuration using a multicapacitor array
J Neurophysiol. 2012 May;107(10):2742-55. Epub 2012 Feb 22.

Zeitler, R., Fromherz, P., Zeck, G. (2011)
Extracellular voltage noise probes the interfaces between retina and silicon chip
Applied Physics Letters 99.

Menzler, J., Zeck, G.
Network oscillations in rod-degenerated mouse retinas
J Neurosci. 2011 Feb 9;31(6):2280-91.

Zeck, G., Lambacher, A., Fromherz, P.
Axonal transmission in the retina introduces a small dispersion of relative timing in the ganglion cell population response
PLoS One. 2011;6(6):e20810. Epub 2011 Jun 2.

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