Regenerative medicine I
Our group is engaged in the development and improvement of regenerative therapies for musculoskeletal tissues (cartilage, intervertebral disc, and bone). We focus on cellular aspects during biomaterial development, cell-matrix-interactions and the testing of biomaterials. We are also interested in the development of validated methods for quality control of cell-based medicinal products and the definition of prognostic biomarkers.
Techniques, methods, equipment
Primary cell cultures (chondrocytes, osteoblasts, mesenchymal stem cells) and in vitro differentiation
• Organo-typical culture models, e.g. explant cultures
• In vitro and in vivo models for examination of cell-based biomaterials
• Various biochemical, molecular biological, and immunological analysis
• FACS analytics
• Histology
Services
• Biomaterial testing (e.g. cytotoxicity, cell adhäsion, celular reactions)
• In vitro cell cultures for testing of bio-active substances, e.g bioactivity of growth factors
• Histological examinations
Network
Health area REGiNA (application centre for regenerative medicine between Neckar-Alb and Stuttgart)
Academic partners:
Universities of Heidelberg, Ulm, Tübingen, Reutlingen